Results 201 to 210 of about 21,100 (250)

COL1A1-Enhanced CD44/SLC7A11 Interaction and Cystine Uptake Result in CD34⁺ Foam-Like Macrophage Accumulation in Transplant Arteriosclerosis. [PDF]

Circulation
Wu J, He T, Qi M, Chen L, Yao M, Zhao X, Zhou Q, Zhang W, Huang X, Liu Y, Gong Y, Shi T, Hong Y, Gao H, Weng C, Peng L, Xiao Q, Lu Y, Yuan H, Xu Q, Cai J.   +20 more
europepmc   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, Volume 14, Issue 7, Page 2329-2346, October 2026.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review). [PDF]

Int J Mol Med
Feng X, Zhang J, Ma Q, Sun C.
europepmc   +1 more source

NRF2/xCT‐Mediated Antioxidant Adaptation Attenuates Apoptosis Induced by ASCT2 Inhibition in Prostate Cancer

Cancer Science, Volume 117, Issue 10, Page 2769-2789, October 2026.
ASCT2 inhibition induces ROS accumulation and activates NRF2‐dependent xCT upregulation in prostate cancer. This adaptive response partially supports residual cystine acquisition and glutathione synthesis, whereas combined ASCT2 and xCT inhibition disrupts redox compensation and predominantly promotes apoptotic cell death.
Jiaxing Wei, Yasutaka Yamada, Takaaki Tamura, Masahiro Sugiura, Xue Zhao, Meng Ni, Adilan Aierken, Tomokazu Sazuka, Yusuke Imamura, Shinichi Sakamoto   +9 more
wiley   +1 more source

Dysregulation of the GPX4/ACSL4 axis mediates ferroptosis in neurons of T2DD rats. [PDF]

Front Pharmacol
Wang Y, Wang S, Zhao S, Lei Y, Fan Y, Zheng X, Yang L, Ma Y.   +7 more
europepmc   +1 more source

The Pathological Roles of Cationic Amino Acid Transporters (CATs) in Cancer

Cancer Science, Volume 117, Issue 10, Page 2636-2643, October 2026.
CAT family transporters (SLC7A1–SLC7A4) coordinate arginine allocation within the tumor microenvironment, thereby regulating cancer metabolism, mTORC1 signaling, immune responses, and metastatic progression. Emerging evidence supports context‐dependent roles for SLC7A1–SLC7A3, whereas the physiological and pathological functions of SLC7A4 remain poorly
Thant Thant Myo Oo, Yasuhiro Saito
wiley   +1 more source

Research advances in single-molecule multi-target strategies targeting ferroptosis for colorectal cancer treatment. [PDF]

Am J Cancer Res
Weng Z, Zhu Y, Yin W, Zhang J, Ni L, Deng X, Miao L.   +6 more
europepmc   +1 more source

Traditional Chinese Medicine Formulas in Delaying Aging: From Theoretical Foundations to Molecular Mechanisms and Translational Perspectives

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Aging is a systemic decline in physiological integrity, driving chronic diseases such as neurodegeneration, cardiovascular disorders, and metabolic syndromes. Rapid global population aging urgently demands effective interventions. Traditional Chinese medicine (TCM) formulas, characterized by multi‐component, multi‐target, and multi‐pathway ...
Chenrong Jin, Ding Du, Xiaorui Yu, Xiaoyan Ji, Xiuyun Zhang, Anning Li, Shuang Zu, Bo Qu, Daqing Zhao, Dianpeng Wu, Meichen Liu   +10 more
wiley   +1 more source

Experimental Detection Methods and Clinical Translational Challenges of Disulfidptosis in Cancer. [PDF]

Cells
Han T, Li R, Wang J, Chu Y, Cai L.
europepmc   +1 more source

LncRNA SLC7A11-AS1 suppresses the ferroptosis of bladder cancer cells through regulating SLC7A11 by IGF2BP1 via m6A modification

Journal of Radiation Research and Applied Sciences
Ganshen Yu, Zhihai Deng, Jingyao Huang, Kaizhong Zhang, Caiyong Lai   +4 more
openaire   +1 more source