Post‐stroke administration of TSN significantly reduced infarct volume, neuroinflammation, and improved functional recovery of MCAO mice. TSN alleviated neural oxidative stress, lipid peroxidation, and ferroptosis in MCAO mice. TSN modulated the infiltration of immune cells in MCAO mice in vivo and T cell differentiation in vitro.
Xinyun Li +5 more
wiley +1 more source
Exosomal miR-148a-3p from LPS-Activated Macrophages Promotes M1 Polarization and Ferroptosis-Related Characteristics of Recipient Macrophages by Reducing SLC7A11. [PDF]
Liang J, Cai Y, Shao Y.
europepmc +1 more source
Hesperetin-black phosphorus nanosheets targeting TAMs induce ferroptosis and reverse protumoral polarization to remodel the immune microenvironment. [PDF]
Feng L +5 more
europepmc +1 more source
Ferroptosis in breast cancer: From adipocyte–immune–iron regulation to therapeutic application
Ferroptosis in breast cancer is regulated by an integrated adipocyte–immune–iron network rather than by tumour‐intrinsic pathways alone. Adipocyte‐derived lipid substrates and redox metabolites, immune‐cell‐mediated cytokine signalling and iron‐dependent oxidative stress collectively shape a dynamic ferroptosis ecosystem that can shift tumours towards ...
Juan Sun, Yang Qu, Ru Yao, Yidong Zhou
wiley +1 more source
Regulation of Amino Acid Transporters by Cell Surface Receptors. [PDF]
Brignola C +8 more
europepmc +1 more source
Super‐enhancer‐driven KIAA1522 upregulation suppresses ferroptosis in hepatocellular carcinoma
Critical points: Aberrantly activated SEs drive the overexpression of the oncogene KIAA1522 in HCC. Targeting SEs and knocking down KIAA1522 facilitate ferroptosis in HCC. As a key downstream effector of KIAA1522, ATF4 plays an essential regulatory role in ferroptosis mediated by the oncoprotein. Abstract Background Aberrantly activated super‐enhancers
Xinyang Li +5 more
wiley +1 more source
Plumage coloration is widely recognized as an important component in intraspecific communication. Our aim was to examine the variation of oxidative parameters and their associations with the coloration of two different nestling plumage traits in collared flycatchers (Ficedula albicollis).
Gabriella Kőmüves +5 more
wiley +1 more source
Targeting Ferroptosis to Overcome Radioresistance and Enhance Immunotherapy in Colorectal Cancer. [PDF]
Soltani Tehrani S +4 more
europepmc +1 more source
Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao +4 more
wiley +1 more source
Post-Translational Modification Networks in Ferroptosis: Orchestrating Defense, Drug Resistance, and Therapeutic Opportunities in Hepatocellular Carcinoma. [PDF]
Chen J, Li L, Fang S, Zhou H.
europepmc +1 more source

