Results 201 to 210 of about 23,034 (273)

Disulfidptosis: A Metabolic Cell Death Mechanism with Therapeutic Potential in Cancer. [PDF]

Oncol Res
Zhao W, Wang Q, Zhang J.
europepmc   +1 more source

Astragaloside IV Reprograms Spatial Glycolytic Metabolism in Diabetic Kidney: A Microenvironment‐Targeted Immunometabolic Therapeutic Strategy

Food Frontiers, Volume 7, Issue 3, May 2026.
Diabetic nephropathy (DN) is driven by spatially organized immunometabolic dysfunction. Integrating high‐resolution spatial transcriptomics (10× Visium HD) and metabolomics (MALDI‐MSI), we mapped a pathogenic glycolytic blockade within diabetic kidney microenvironments.
Shi Qiu, Zhibo Wang, Sifan Guo, Dandan Xie, Ying Cai, Xian Wang, Yan Wang, Xiaodan Yu, Jinxuan Chai, Hong Yao, Chunsheng Lin, Qiang Yang, Yu Guan, Qiqi Zhao, Songqi Tang, Wenjie Sun, Yiqiang Xie, Aihua Zhang   +17 more
wiley   +1 more source

Hypoxia-Induced Ferroptosis Resistance Drives Orbital Fibrosis in Thyroid Eye Disease. [PDF]

Invest Ophthalmol Vis Sci
Gong C, Liu S, Zhao J, Zhu J, Xing C, Li K, Xie C, Wu N, Chen R.   +8 more
europepmc   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source

Epigenetic modifications in ferroptosis regulation of breast cancer. [PDF]

Am J Cancer Res
Lin L, Wang Y, Si W, Liu X.
europepmc   +1 more source

Efferocytosis: Signaling Pathways and New Therapeutic Strategies for Diseases

MedComm, Volume 7, Issue 5, May 2026.
1. Efferocytosis coordinates molecular signaling and metabolic reprogramming to resolve inflammation. 2. Efferocytosis dysfunction underlies four conserved pathological hallmarks across diseases. 3. Therapeutic strategies targeting efferocytosis should be context‐dependent: enhance or inhibit based on disease type. ABSTRACT Efferocytosis—the phagocytic
Lei Wang, Jingjing Ge, Zehua Wang, Yihua Fang, Yongxu Jia, Ruyue Zhang, Yanru Qin   +6 more
wiley   +1 more source

Targeting Ferroptosis With Natural Products for the Treatment of Skeletal System Disease: An Updated Review. [PDF]

J Cell Mol Med
Yi Q, Li J, Luo G, Li J, Yang D, Sun W, Sun W, You W, Yang L.   +8 more
europepmc   +1 more source

Cutibacterium acnes–Derived Extracellular Vesicles Promote Epithelial Ovarian Cancer Progression by Activating the KEAP1–NRF2 Antioxidant Pathway to Suppress Ferroptosis

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
C. acnes‐derived extracellular vesicles promote epithelial ovarian cancer progression. CEVs reprogram redox homeostasis and suppress ferroptosis by modulating key regulators. ABSTRACT Bacterial extracellular vesicles are increasingly recognized as important mediators of microbe–host communication, yet their functional roles within tumour‐associated ...
Qifa Huang, Qi Chen, Wenjie Xiong, Yuexi Sun, Yuxiong Huang, Ang Dai, Jianying Chen, Xue Wu, Ying Jiang, Fen Wei, Qi Chen, Tingtao Chen   +11 more
wiley   +1 more source

Molecular mechanism of Yishen Qingzhuo oral liquid in treating chronic renal failure <i>via</i> the Nrf2/HO-1-mediated ferroptosis pathway. [PDF]

Ren Fail
Zhao A, Chen B, Lin C, Wang W, Su H, Qiu Y, Zhang W.   +6 more
europepmc   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source