Results 211 to 220 of about 20,364 (275)

Danshensu Ethyl Ester Induces Ferroptosis Through Targeted Inhibition of SLC7A11 Transport Function in NSCLC. [PDF]

Thorac Cancer
Yan R, Xu S, Yan M, Wu D, Zhang J, Zhang C, Liu J, Li YJ, Feng J, Qu GW, Xie SY.   +10 more
europepmc   +1 more source

Pathogenesis of Osteoarthritis: Mechanisms of Action of Disulfidptosis and Targeted Therapeutic Strategies. [PDF]

Drug Des Devel Ther
Liang Y, Wang K, Yang C, Huang J, Huang Z, Chen Y.   +5 more
europepmc   +1 more source

HIV Tat‐Stimulated Microglial Extracellular Vesicles Are Enriched for Ferroptosis Mediators: Role of Dysregulated Autophagy

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) serve as conduits for intercellular communication, under both physiological and pathological contexts. During disease pathogenesis, microglia‐derived EVs (MEVs) play a key role in transferring pathological cargo to the recipient cells, thereby modulating their phenotype and function.
Seema Singh, Elias Horanieh, Craig L. Semerad, Palsamy Periyasamy, Susmita Sil, Shilpa Buch   +5 more
wiley   +1 more source

Sestrin2 Mitigates Neuronal Ferroptosis Following Subarachnoid Hemorrhage via Orchestration of the AMPK/PGC1α/Nrf2 Signaling Axis. [PDF]

CNS Neurosci Ther
Zhang Y, Wan X, Zhang H, Chen Z, Xiao S, Wang W, Wang J, Zheng R, Chen X, Yang Y.   +9 more
europepmc   +1 more source

USP54 Promotes Ferroptosis in Non‐Small Cell Lung Cancer by Mediating FOXA2 Deubiquitination and Enhancing ACSL4 Transcription

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT Non‐small cell lung cancer (NSCLC) is the most common type of lung cancer, with a 5‐year survival rate of less than 20% and a high risk of recurrence despite advances in treatment. This study aimed to identify new therapeutic targets to increase the effectiveness of NSCLC treatments.
Rui‐Shi Wei, Yong‐Ping Liu, Chun‐Dong Gu, Shi‐Lei Zhao, Li Feng, Jian‐Rong Yu   +5 more
wiley   +1 more source

Exploring and experimental validation of SLC7A11 and ferroptosis related prognostic genes in non-small cell lung cancer using bulk RNA sequencing and single-cell RNA sequencing. [PDF]

Biol Direct
Diao X, Pan S, Duan Y, Di L.
europepmc   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Peripheral Circulating Exosomes Induce Sepsis-associated Liver Injury by Up-regulating STAT1 to Promote Autophagy and Regulating the SLC7A11-GSH-GPX4 Axis to Promote Ferroptosis. [PDF]

Inflammation
Tang YJ, Du X, Yin B, Liu HY, Tang YJ, Zhang ZY, Meng QM, Zhang Y, Deng JL, Li Y, Yang PL, Kang K, Zhao MY, Gao Y.   +13 more
europepmc   +1 more source

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou, Sheng He, Lili He, Kun Liu, Wen Tang, Deming Wang, Jing Gui, Zhiying Zeng, Yan Wang, Wenjie Liu, Ren Jing   +10 more
wiley   +1 more source

UFM1 regulates ferroptosis in oral squamous cell carcinoma by stabilizing SLC7A11. [PDF]

Am J Cancer Res
Li G, Yang H, Guo J.
europepmc   +1 more source