Results 211 to 220 of about 23,034 (273)

Low KIF26B Expression Reduces Paclitaxel Resistance and Predicts Good Prognosis in Ovarian Cancer. [PDF]

Curr Issues Mol Biol
Su Y, Liu X, Yu Y, Chen X, Shi L, Du Z, Mao Y, Yin F.   +7 more
europepmc   +1 more source

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

The FEBS Journal, Volume 293, Issue 9, Page 2637-2655, May 2026.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese, Chiara Brignola, Stefano Marrone, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo   +5 more
wiley   +1 more source

Mechanistic Role of Disulfidptosis in Type 2 Diabetes Mellitus. [PDF]

Mol Nutr Food Res
Zou D, Zou Y, Jin Y, Liu S, Lin M, Deng R, Nan Z.   +6 more
europepmc   +1 more source

EIF2α–ATF4–CHAC1 Signalling Links ER Stress to Ferroptosis in Human Aortic Smooth Muscle Cells: Mechanistic Insights and Therapeutic Implications

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Ferroptosis—a regulated, iron‐dependent cell death driven by lipid peroxidation—has been implicated in vascular pathology, yet how endoplasmic reticulum (ER) stress couples to ferroptotic execution in vascular smooth muscle cells (VSMCs) remains unclear.
Changwen Fang, Xiaolong Du, Yadan Wang, Yiqi Jin, Wenbin Wang   +4 more
wiley   +1 more source

Traditional Chinese Herbal Formula XuMingZhuSan Alleviates Neuronal Ferroptosis in Rats After Stroke by Activating the NRF2/GPX4/SLC7A11 Pathway. [PDF]

Food Sci Nutr
Liu X, Wang C, Han L, Xiao Y, Yu H, Hu Z, Fei X, Peng M, Zhou J, Zhong Z.   +9 more
europepmc   +1 more source

Exosomal Non‐Coding RNAs in Gastrointestinal Cancer Drug Resistance: A Systematic Review of Emerging Mechanisms and Clinical Implications

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Gastrointestinal (GI) tumours are one of the most prevalent cancers globally. Even with normal GI function, individuals may develop neoplasms, highlighting the need to better understand the underlying causes of tumorigenesis. The emergence of tumour drug resistance represents the main reason for the failure of drug treatment; thus, it is ...
Mohsen Sharif‐zak, Zahra Sadeghloo, Fateme Binayi, Stefania Nobili, Sara Ashtari, Amir Sadeghi, Nayeralsadat Fatemi   +6 more
wiley   +1 more source

Homoplantaginin protects pancreatic tissue in severe acute pancreatitis mice via inhibiting ferroptosis by modulating the circDNMT3B/miR-20b-5p/SLC7A11 axis. [PDF]

BMC Gastroenterol
Teng X, Sheng S, Pan M, Li Y, Li Z.
europepmc   +1 more source

Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers [PDF]

, 2008
Christina Yau, Christopher C Benz, KB Horwitz, V-J Bardou, PM Ravdin, EA Rakha, DFd Hull, GE Gross, J Quong, X Cui, X Cui, H-J Kim, G Arpino, HM Lander, Q Felty, TD Oberley, MM Patel, HK Bhat, SH Dairkee, X Liang, X Wu, GK Scott, M Valko, ER Levin, T Kirkegaard, JM Knowlden, SM Nabha, JM Gee, AS Oh, CJ Creighton, C Creighton, Y-YE Chuang, R Gentleman, VG Tusher, C Yau, LD Miller, KR Hess, M Benito, Y Gong, A Subramanian, CM Perou, Z Hu, MB Eisen, AJ Saldanha, B Williams, PD Leotlela, H-J Chen, T Shibata, KR Coser, C-Y Lin, DS Oh, JA Vendrell, R Whittal, C Atsriku, T Itoh, R Santen, WR Miller, JS Carroll, HJ Huang, H-J Huang, H Weedon-Fekjaer, N Brown, RG Allen, RB Dickson, B Yi, R Serra, I Bieche, M Nagai, J Beattie, M Becker, Z Sheng, J Yan, AM Fulton, G Dennis   +73 more
core   +1 more source

FOXC1‐ATP7A Axis Activates PI3K/AKT Signaling to Suppress Cuproptosis and Drive Fibroblast Pathogenesis in Rheumatoid Arthritis

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
This graphical abstract illustrates the regulatory mechanism of the FOXC1‐ATP7A axis in Rheumatoid Arthritis (RA). Bioinformatics analysis identifies FOXC1 as a hub transcription factor that is significantly upregulated in RA synovial tissues and fibroblast‐like synoviocytes (FLSs).
Daomin Lu, Fang Tang, Zong Jiang, Wukai Ma, Changming Chen, Lei Hou, Qianwei Lu, Xueming Yao, Danyang Li, Weiya Lan   +9 more
wiley   +1 more source

Solasonine inhibits NSCLC malignant progression by regulating SLC7A11 ubiquitination degradation and inducing ferroptosis. [PDF]

Respir Res
Wang Y, Li X, Zhou C, Qian M, Zou Z, Yang W, Wilfred NSJ, Huang G, Xu X, Xue F, Jin M.   +10 more
europepmc   +1 more source