Results 81 to 90 of about 19,150 (245)
Journal of Inflammation ResearchChen Y, Deng Y, Chen L, Huang Z, Yan Y, Huang Z. J Inflamm Res. 2023;16:1077–1089. We, the Editors and Publisher of Journal of Inflammation Research, have retracted the following article.
Chen Y +5 more
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Cancer Management and Research, 2019 Jing Ye, Xiaohua Jiang, Zhihuai Dong, Sunhong Hu, Mang Xiao Department of Otolaryngology Head and Neck Surgery, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of ChinaCorrespondence: Mang ...
Ye J, Jiang X, Dong Z, Hu S, Xiao M
doaj
Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
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Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis
Genes & DiseasesAlthough cell-cycle arrest, senescence, and apoptosis are well accepted as the classic barriers in tumorigenesis, recent studies indicate that metabolic regulation is equally important as a major checkpoint in cancer development. It is well accepted that ferroptosis, an iron-dependent programmed cell death, acts as a new type of tumor suppression ...
Zhenyi Su, Yanqing Liu, Lin Wang, Wei Gu
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Interdisciplinary Medicine, EarlyView.Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu +6 more
wiley +1 more source
Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration
Neural Regeneration ResearchJOURNAL/nrgr/04.03/01300535-202601000-00043/figure1/v/2026-04-22T161640Z/r/image-tiff Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss.
Xiaoxu Huang +11 more
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Biomedical JournalBackground: SLC7A11, a plasma membrane protein, has been implicated as an oncogene in various cancers, including hepatocellular carcinoma (HCC). Its role in HCC pathogenesis, particularly in relation to ferroptosis, is not well understood.
Yan An +4 more
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Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells
Interdisciplinary Medicine, EarlyView.Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen +6 more
wiley +1 more source
SLC7A11: a new regulator in diabetic wound healing
Signal Transduction and Targeted Therapy, 2022 Shunli Rui, Yu Ma, Wuquan Deng
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Essentiality of SLC7A11-mediated nonessential amino acids in MASLD
Science BulletinMetabolic dysfunction-associated steatotic liver disease (MASLD) remains a rapidly growing global health burden. Here, we report that the nonessential amino acid (NEAA) transporter SLC7A11 plays a key role in MASLD. In patients with MASLD, we found high expression levels of SLC7A11 that were correlated directly with clinical grade.
Jie, Shen +6 more
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