Results 41 to 50 of about 2,201 (173)
Biomedicines, 2022 In mammalian cells, the content of polyamines is tightly regulated. Polyamines, including spermine, spermidine and putrescine, are involved in many cellular processes. Spermine oxidase specifically oxidizes spermine, and its deregulated activity has been
Manuela Cervelli +10 more
doaj +1 more source
Cross reaction of selected SMABs against rmSMOX.
, 2022 Western blot assessing the reactivity of selected SMABs towards recombinantly expressed human and murine SMOX (1ug SMOX per lane; 1:1000 dilution of primary detection SMAB).
Vincent N. A. Klaren (12446918) +5 more
core +1 more source
Anterograde Activin signaling regulates postsynaptic membrane potential and GluRIIA/B abundance at the Drosophila neuromuscular junction. [PDF]
PLoS ONE, 2014 Members of the TGF-β superfamily play numerous roles in nervous system development and function. In Drosophila, retrograde BMP signaling at the neuromuscular junction (NMJ) is required presynaptically for proper synapse growth and neurotransmitter ...
Myung-Jun Kim, Michael B O'Connor
doaj +1 more source
Toxicological Sciences, 2018 Spermine oxidase (Smox) is a member of the polyamine oxidases and has been demonstrated to be involved in ischemic brain damage. In this study, we found that Smox expression was increased in a rat middle cerebral artery occlusion (MCAO) model and in cultured primary neurons after oxygen-glucose deprivation and reoxygenation (OGD/R). Smox downregulation
Jiawei, Fan +8 more
openaire +2 more sources
Inhibition of Polyamine Catabolism Reduces Cellular Senescence
, 2023 The aging of the global population has necessitated the identification of effective anti-aging technologies based on scientific evidence. Polyamines (putrescine, spermidine, and spermine) are essential for cell growth and function. Age-related reductions
Yuka Yokota +4 more
core +1 more source
Muscle expression of smox transgene rescues the defective phenotypes of smox mutants.
, 2014 (A) Quantification of GluRIIA abundance. The decreased GluRIIA level exhibited by smox mutants is rescued over the level of control animals (smoxf4;UAS-smox/+) and even the wild-type only when the smox transgene is expressed via the muscle driver, Mef2 ...
Michael B. O’Connor (634750) +1 more
core +1 more source
Chemosensors, 2021 Gas sensing materials, such as semiconducting metal oxides (SMOx), carbon-based materials, and polymers have been studied in recent years. Among of them, SMOx-based gas sensors have higher operating temperatures; sensors crafted from carbon-based ...
Bo Huang, Yanqiong Li, Wen Zeng
doaj +1 more source
, 2021 Representative images and quantitation of total DCP1+ Elav+ cells (2-A’; 2B-B’) or DadnGFP+ Elav+ cells (2A”-S2A”‘; 2B”-S2B”‘) in maturing GMR::Gal4;Dad-nGFP/ Sax-RNAi and Smox-RNAi progeny compared to controls.
Mia Koniikusic (11607903) +4 more
core +1 more source
Sugar-responsive transcription factors Cabut and Smox are regulated by Grain.
, 2021 A. mRNA expression (RNA-seq) of transcription factor cabut (cbt) is downregulated upon grain knockdown (Tub-GAL4>grain RNAi BDSC #27658) as compared to control (Tub-GAL4>TriP control BDSC #31603) 2nd instar larvae on low sugar diet (N = 4, 20 per group).
Anni I. Nieminen (11547673) +9 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt +18 more
wiley +1 more source