Results 11 to 20 of about 2,372,069 (151)

Pro-Resolving Inflammatory Effects of a Marine Oil Enriched in Specialized Pro-Resolving Mediators (SPMs) Supplement and Its Implication in Patients with Post-COVID Syndrome (PCS) [PDF]

Biomedicines
Objectives: This study aimed to evaluate the eicosanoid and pro-resolutive parameters in patients with Post-COVID Syndrome (PCS) during a 12-week supplementation with a marine oil enriched in specialized pro-resolving mediators (SPMs).
Asun Gracia Aznar, Fernando Moreno Egea, Rafael Gracia Banzo, Rocio Gutierrez, Jose Miguel Rizo, Pilar Rodriguez-Ledo, Isabel Nerin, Pedro-Antonio Regidor   +7 more
doaj   +6 more sources

PCOS: A Chronic Disease That Fails to Produce Adequately Specialized Pro-Resolving Lipid Mediators (SPMs)

Biomedicines, 2022
Introduction: Polycystic ovary syndrome (PCOS) is an endocrinological disorder that affects 5–15% of women of their reproductive age and is a frequent cause of infertility. Major symptoms include hyperandrogenism, ovulatory dysfunction, and often obesity
Pedro-Antonio Regidor, Xavier de la Rosa, Anna Müller, Manuela Mayr, Fernando Gonzalez Santos, Rafael Gracia Banzo, Jose Miguel Rizo   +6 more
doaj   +4 more sources

Specialized Pro-Resolving Mediators in Neuroinflammation: Overview of Studies and Perspectives of Clinical Applications [PDF]

Molecules, 2022
Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in the inflammation environment, preventing an overreaction of the organism and ...
Mariarosaria Valente, Marta Dentoni, Fabrizio Bellizzi, Fedra Kuris, Gian Luigi Gigli   +4 more
doaj   +4 more sources

The Use of Specialized Pro-Resolving Mediators in Biomaterial-Based Immunomodulation

Journal of Functional Biomaterials, 2023
The implantation of a biomaterial will lead to the immediate onset of an acute inflammatory response, which is of key importance in shaping the quality of the repair process.
Ana Beatriz Sousa, Judite N. Barbosa
doaj   +4 more sources

Specialized Pro-Resolving Lipid Mediators in Neonatal Cardiovascular Physiology and Diseases

Antioxidants, 2021
Cardiovascular disease remains a leading cause of mortality worldwide. Unresolved inflammation plays a critical role in cardiovascular diseases development.
Andrea Gila-Diaz, Gloria Herranz Carrillo, Pratibha Singh, David Ramiro-Cortijo   +3 more
doaj   +4 more sources

Targeted Delivery of Specialized Pro-Resolving Mediators (SPMs) for Improved Treatments of Inflammatory Diseases and Cancer [PDF]

Pharmaceutics
Acute and chronic inflammation underlies the pathogenesis of numerous diseases, including autoimmune disorders, atherosclerosis, infections, and cancer.
Adeola Aminu, Zhenjia Wang
doaj   +3 more sources

Specialized Pro-Resolving Mediators at the Ocular Surface: Biosynthesis, Mechanisms, and Therapeutic Potential [PDF]

Biology
Specialized pro-resolving mediators (SPMs) are endogenous lipid mediators that actively orchestrate the resolution of inflammation rather than relying solely on broad suppression of inflammatory signaling.
Siddharth Gandhi, Arveen Shokravi, Sydney Buhrow, Michael Balas   +3 more
doaj   +3 more sources

Specialized Pro-Resolving Mediators as Potential Regulators of Inflammatory Macrophage Responses in COVID-19

Frontiers in Immunology, 2021
The recent outbreak of SARS-CoV2 has emerged as one of the biggest pandemics of our century, with outrageous health, social and economic consequences globally.
Maria G. Balta, Evangelos Papathanasiou, Evangelos Papathanasiou, Panagiotis F. Christopoulos   +3 more
doaj   +2 more sources

Specialized Pro-resolving Mediators Regulate Alveolar Fluid Clearance during Acute Respiratory Distress Syndrome

Chinese Medical Journal, 2018
Objective: Acute respiratory distress syndrome (ARDS) is an acute and lethal clinical syndrome that is characterized by the injury of alveolar epithelium, which impairs active fluid transport in the lung, and impedes the reabsorption of edema fluid from ...
Qian Wang, Song-Fan Yan, Yu Hao, Sheng-Wei Jin   +3 more
doaj   +2 more sources

Resolvins, Protectins, and Maresins: DHA-Derived Specialized Pro-Resolving Mediators, Biosynthetic Pathways, Synthetic Approaches, and Their Role in Inflammation

Molecules, 2022
Marine organisms are an important source of natural products with unique and diverse chemical structures that may hold the key for the development of novel drugs.
Inês Ferreira, Filipa Falcato, Narcisa Bandarra, Amélia P. Rauter   +3 more
doaj   +2 more sources