Results 41 to 50 of about 56,045 (256)

Exogenous Spermidine Promotes Germination of Aged Sorghum Seeds by Mediating Sugar Metabolism

Plants, 2022
Starch, a substance stored in seeds, is the main source of energy for germination in sorghum seeds. However, as the seeds age, the catabolism of seed starch is affected, thereby seriously damaging germination ability.
Min Zhang, Bang Li, Zuliang Wan, Xiaofei Chen, Chang Liu, Chunjuan Liu, Yufei Zhou   +6 more
doaj   +1 more source

Spermidine intake is associated with cortical thickness and hippocampal volume in older adults

NeuroImage, 2020
Background: The natural polyamine spermidine, known to be important for cellular function, decreases during aging. Previous research has demonstrated beneficial impact of spermidine intake on memory functions in both animal models and humans, suggesting ...
Claudia Schwarz, Nora Horn, Gloria Benson, Isabel Wrachtrup Calzado, Katharina Wurdack, Raimund Pechlaner, Ulrike Grittner, Miranka Wirth, Agnes Flöel   +8 more
doaj   +1 more source

Spermidine Modify Antioxidant Activity in Cucumber Exposed to Salinity Stress

Agronomy, 2022
The effects of short-term 48 h long NaCl-stress and spermidine level modification on polyamines level and antioxidant status in cucumber (Cucumis sativus cv. Dar) leaves were investigated.
Agata Korbas, Jan Kubiś, Magdalena Rybus-Zając, Tamara Chadzinikolau   +3 more
doaj   +1 more source

MAGHEMITE PARTICLES FOR SPERMIDINE SEPARATION [PDF]

NANOCON Conference Proeedings, 2020
We report the optimal conditions for the separation of spermidine from different types of samples, for example blood or cancer cells and its subsequent determination by ion-exchange liquid chromatography (IEC) with UV-VIS detector. Here in, we synthesized paramagnetic particles able to isolate and immobilize spermidine from blood of patients with ...
Kopel, Pavel, Cernei, Natalia Vladimirovna, Horký, Pavel, Lacková, Zuzana, Milosavljević, Vedran, Gagić, Milica, Zítka, Ondřej, Adam, Vojtěch   +7 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Inhibition of Ornithine Decarboxylase 1 Mitigates Denervation-Induced Muscle Atrophy by Suppressing Proteolysis and Preserving Muscle Stem Cell Homeostasis. [PDF]

Cell Prolif
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Zhang M, Chang F, Ge S, Cao F, Fu P, Zhang H, Chen M, Li Y, Tang P, Yin P.   +9 more
europepmc   +2 more sources

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Spermidine-induced improvements in water relations and antioxidant defense enhance drought tolerance in yarrow (Achillea millefolium L.)

Heliyon
Drought stress poses a serious threat to agricultural productivity worldwide. This study investigated the mitigative effects of exogenous spermidine on drought stressed yarrow (Achillea millefolium L.). Plants were subjected to three drought levels (25 %,
Sajedeh Alijani, Mohammad-Reza Raji, Zohreh Emami Bistgani, Abdollah Ehtesham Nia, Mostafa Farajpour   +4 more
doaj   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

Spermidine

, 2002
Inelastic Neutron Scattering spectrum of Spermidine, H₂N(CH₂)₃NH(CH₂)₃NH₂, measured on the TOSCA ...
M. P. M. Marques, Universidade de Coimbra, Portugal
core   +1 more source