Results 11 to 20 of about 241 (129)
Molecular Cloning of Plant Spermidine Synthases [PDF]
Plant and Cell Physiology, 1998 Four cDNAs for spermidine synthase (SPDS), which converts the diamine putrescine to the higher polyamine spermidine using decarboxylated S-adenosylmethionine as the co-factor, were isolated from Nicotiana sylvestris, Hyoscyamus niger, and Arabidopsis thaliana. When the N.sylvestris SPDS cDNA was expressed in a SPDS-deficient E.
T, Hashimoto +3 more
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Studies of inhibition of rat spermidine synthase and spermine synthase [PDF]
Biochemical Journal, 1980 1. S-Adenosyl-l-methionine, S-adenosyl-l-homocysteine, 5′-methylthioadenosine and a number of analogues having changes in the base, sugar or amino acid portions of the molecule were tested as potential inhibitors of spermidine synthase and spermine synthase from rat ventral prostate. 2. S-Adenosyl-l-methionine was inhibitory to these reactions, as were
H, Hibasami +4 more
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Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish
Biology Open, 2016 Polyamines are small poly-cations essential for all cellular life. The main polyamines present in metazoans are putrescine, spermidine and spermine.
Hans Georg Frohnhöfer +10 more
doaj +1 more source
Response to Cadmium Toxicity: Orchestration of Polyamines and microRNAs in Maize Plant
Plants, 2023 Cadmium (Cd) is a heavy metal that is widely contaminating the environment due to its uses in industries as corrosive reagents, paints, batteries, etc.
Seyedeh Batool Hassani +12 more
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Medical Sciences, 2021 Polyamines are small organic cations that are important for several biological processes such as cell proliferation, cell cycle progression, and apoptosis.
Tahj S. Morales +5 more
doaj +1 more source
Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome
EMBO Molecular Medicine, 2023 Snyder–Robinson syndrome (SRS) results from mutations in spermine synthase (SMS), which converts the polyamine spermidine into spermine. Affecting primarily males, common manifestations of SRS include intellectual disability, osteoporosis, hypotonia, and
Tracy Murray Stewart +8 more
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Spermidine Synthase Is Required for Virulence of Leishmania donovani [PDF]
Infection and Immunity, 2011 ABSTRACT Genetic lesions in the polyamine biosynthetic pathway of Leishmania donovani , the causal agent of visceral leishmaniasis, are conditionally lethal mutations that render the insect vector form of the parasite auxotrophic for polyamines. Recently, we have demonstrated that a Δ odc
Caslin, Gilroy +3 more
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Frontiers in Plant Science, 2021 Soil arbuscular mycorrhizal fungi (AMF) enhance the tolerance of plants against soil moisture deficit stress (SMDS), but the underlying mechanisms are still not fully understood. Polyamines (PAs) as low-molecular-weight, aliphatic polycations have strong
Ying-Ning Zou +5 more
doaj +1 more source
Characterization of transgenic mice with overexpression of spermidine synthase [PDF]
Amino Acids, 2011 A composite cytomegalovirus-immediate early gene enhancer/chicken β-actin promoter (CAG) was utilized to generate transgenic mice that overexpress human spermidine synthase (SpdS) to determine the impact of elevated spermidine synthase activity on murine development and physiology.
Chenxu, Shi +6 more
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Spermidine Synthase Genes Are Essential for Survival of Arabidopsis [PDF]
Plant Physiology, 2004 Abstract The cellular polyamines putrescine, spermidine, and spermine are ubiquitous in nature and have been implicated in a wide range of growth and developmental processes. There is little information, however, on mutant plants or animals defective in the synthesis of polyamines. The Arabidopsis genome has two genes encoding spermidine
Akihiro, Imai +12 more
openaire +2 more sources