Results 101 to 110 of about 23,449 (215)
The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence
AgriFood: Journal of Agricultural Products for Food, Volume 2, Issue 3, Page 262-284, September 2026.Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John +4 more
wiley +1 more source
Sphingomyelinase in normal human spleens and in spleens from subjects with Niemann-Pick disease
Journal of Lipid Research, 1967 This paper describes the purification and some of the properties of an enzyme from human spleen that catalyzes the hydrolysis of sphingomyelin with the formation of ceramide and phosphoryl choline.
Peter B. Schneider, Eugene P. Kennedy
doaj +1 more source
, 2018 Staphylococcus aureus ( S. aureus ) infections are among the most common and severe infections, garnering notoriety in an era of increasing resistance to antibiotics.
Michael J. Edwards +15 more
core +1 more source
Enterotoxin Production of Bacillus thuringiensis Isolates From Biopesticides, Foods, and Outbreaks
Frontiers in Microbiology, 2018 While the relevance of Bacillus (B.) cereus as a major cause of gastroenteritis is undisputed, the role of the closely related B. thuringiensis in foodborne disease is unclear. B. thuringiensis strains frequently harbor enterotoxin genes.
Sophia Johler +9 more
doaj +1 more source
Lack of costimulation by both sphingomyelinase and C2 ceramide in resting human T cells
, 2000 Resting T cells require a signal transduced through their antigen-specific T-cell receptor (TCR) and an antigen-independent costimulatory signal in order to proliferate and become activated. Ligation of the CD28 receptor costimulates T-cell proliferation
Sansom, David, O'Byrne, D
core +1 more source
Plasma Membrane Lipid Domains as Platforms for Vesicle Biogenesis and Shedding?
Biomolecules, 2018 Extracellular vesicles (EVs) contribute to several pathophysiological processes and appear as emerging targets for disease diagnosis and therapy. However, successful translation from bench to bedside requires deeper understanding of EVs, in particular ...
Hélène Pollet +3 more
doaj +1 more source
, 2017 Objective: We aimed to identify the role of the enzyme acid sphingomyelinase in the aging of stored units of packed red blood cells (pRBCs) and subsequent lung inflammation after transfusion.
Kleuser, Burkhard (Prof. Dr. rer. nat.) +10 more
core +1 more source
Rolle der sauren Sphingomyelinase bei der Aktivierung von T-Lymphozyten
, 2018 Die Saure Sphingomyelinase und Ceramid modulieren diverse Aspekte der T-Zellaktivierung. T-Lymphozyten kommt bei der adaptiven Immunabwehr von Pathogenen eine zentrale Rolle zu.
Begum, Salina
core
Secretory sphingomyelinase in health and disease
Biological Chemistry, 2015 AbstractAcid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, hydrolyzes sphingomyelin to ceramide and phosphorylcholine. In mammals, the expression of a single gene,SMPD1,results in two forms of the enzyme that differ in several characteristics.
Johannes, Kornhuber +3 more
openaire +2 more sources
Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae [PDF]
, 2000 The interaction with human phagocytes is a hallmark of symptomatic Neisseria gonorrhoeae infections. Gonococcal outer membrane proteins of the Opa family induce the opsonin-independent uptake of the bacteria that relies on CEACAM receptors and an active ...
K. Ferlinz +22 more
core +1 more source