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Sphingomyelinase in Pig and Human Epidermis

Journal of Investigative Dermatology, 1978
The enzyme sphingomyelinase (sphingomyelin phosphorylcholine phosphohydrolase E.C.3.1.4.12) which hydrolyzes sphingomyelin to ceramide (N-acylsphingosine) and phosphorylcholine was identified in the subcellular fractions of pig and human epidermis. The enzyme has an optimum pH of 4.5 to 5 and is activated by Triton X-100 (0.1% w/v).
Bowser, Paul A., Maurice Gray, G.
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Relationship Between Plasma Acid Sphingomyelinase and Alteration in Taste and Smell as Indicator of Long COVID in Pregnant Women

Reports
Background: Persistent alterations in taste and smell affect a significant proportion of individuals following COVID-19, representing a component of post-acute COVID-19 syndrome, commonly referred to as long COVID.
Federico Fiorani +11 more
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Progression of neurovisceral storage disease with supranuclear ophthalmoplegia following orthotopic liver transplantation [PDF]

, 1986
A 7-year-old girl with progressive ataxia, spasticity, supranuclear ophthalmoplegia, and sea-blue histiocytes in her bone marrow underwent orthotopic liver transplantation for hepatocellular carcinoma.
Bergman, I +8 more
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Brush border digestion : development of a physiologically relevant in vitro model : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Physiology at Massey University, Manawatū, New Zealand [PDF]

, 2018
Chapter Two has, in part, been published in the Springer publication, Reviews of Physiology, Biochemistry and Pharmacology, but the Author retains the right to publish the material in any collection consisting of the Author's own works: Hooton, D ...
Hooton, Diane Frances
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Sphingomyelinase [PDF]

, 2018
K. J. Lackner, D. Peetz
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Molecular mechanism of bacterial sphingomyelinase C

Nippon Saikingaku Zasshi, 2011
ウエルシュ菌のガス壊疽の病原因子であるα毒素（Cp-SMase）は，スフィンゴミエリン（SM）とホスファチジルコリン（PC）を分解する活性を有し，致死，壊死，そして，溶血活性を示す毒素である。セレウス菌のスフィンゴミエリナーゼ（Bc-SMase）は，致死，壊死活性を示さないが，リン脂質組成として，ホスファチジルコリンを含まず，スフィンゴミエリン（SM）を50％以上有するヒツジ赤血球に対して溶血作用を示す。Cp-SMaseは，細胞膜中でグリセロリン脂質の代謝亢進を惹起することによってラットの血管平滑筋の収縮やウサギ赤血球の溶血を引き起こすことが明らかにされてきたが，Bc-SMaseの作用機構に関しては不明であった。そこで，毒素作用とスフィンゴミエリナーゼ（SMase）活性の関係を解明するため ...
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Sphingomyelinase [PDF]

, 2011
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Influence of pH control in the formation of inclusion bodies during production of recombinant sphingomyelinase-D in Escherichia coli [PDF]