Results 81 to 90 of about 18,841 (183)

Ceramides and sphingomyelinases in senile plaques

Neurobiology of Disease, 2014
The senile plaque is a hallmark lesion of Alzheimer disease (AD). We compared, without a priori, the lipidome of the senile plaques and of the adjacent plaque-free neuropil. The analysis by liquid chromatography coupled with electrospray ionization mass spectrometry revealed that laser microdissected senile plaques were enriched in saturated ceramides ...
Panchal, Mai, Gaudin, Mathieu, Lazar, Adina, Salvati, Elisa, Rivals, Isabelle, Ayciriex, Sophie, Dauphinot, Luce, Dargère, Delphine, Auzeil, Nicolas, Masserini, Massimo, Laprévote, Olivier, Duyckaerts, Charles   +11 more
openaire   +3 more sources

Apoptosis and signalling in acid sphingomyelinase deficient cells

BMC Cell Biology, 2001
Background Recent evidence suggests that the activation of a non-specific lipid scramblase during apoptosis induces the flipping of sphingomyelin from the cell surface to the cytoplasmic leaftet of the plasma membrane. Inner leaflet sphingomyelin is then
Sillence Dan J
doaj   +1 more source

Sphingomyelinase in Pig and Human Epidermis

Journal of Investigative Dermatology, 1978
The enzyme sphingomyelinase (sphingomyelin phosphorylcholine phosphohydrolase E.C.3.1.4.12) which hydrolyzes sphingomyelin to ceramide (N-acylsphingosine) and phosphorylcholine was identified in the subcellular fractions of pig and human epidermis. The enzyme has an optimum pH of 4.5 to 5 and is activated by Triton X-100 (0.1% w/v).
Bowser, Paul A., Maurice Gray, G.
openaire   +2 more sources

Sphingomyelinase treatment of low density lipoprotein and cultured cells results in enhanced processing of LDL which can be modulated by sphingomyelin.

Journal of Lipid Research, 1992
The addition of neutral sphingomyelinase from S. aureus to the medium of rat intestinal epithelial cell cultures (IEC-6) containing added human low density lipoprotein (LDL) resulted in two- to fivefold increases in LDL uptake and degradation.
AK Gupta, H Rudney
doaj   +1 more source

Relationship Between Plasma Acid Sphingomyelinase and Alteration in Taste and Smell as Indicator of Long COVID in Pregnant Women

Reports
Background: Persistent alterations in taste and smell affect a significant proportion of individuals following COVID-19, representing a component of post-acute COVID-19 syndrome, commonly referred to as long COVID.
Federico Fiorani, Giulia Moretti, Laura Cerquiglini, Chiara Gizzi, Giulia Gizzi, Paola Signorelli, Samuela Cataldi, Tommaso Beccari, Elisa Delvecchio, Claudia Mazzeschi, Stefania Troiani, Elisabetta Albi   +11 more
doaj   +1 more source

Sphingomyelinase [PDF]

, 2018
K. J. Lackner, D. Peetz
openaire   +2 more sources

Sphingomyelinase [PDF]

, 2011
openaire   +2 more sources

Contradictory Effects on Hepatocytes in ASMD. [PDF]

Int J Mol Sci
Sysoev M, Solovyov D, Shestopalov A, Kutsev S.   +3 more
europepmc   +1 more source

Acid sphingomyelinase deficiency: Phenotypic, biochemical, and molecular heterogeneity in a series of 47 Iraqi patients from a single center. [PDF]

Mol Genet Metab Rep
Farhan R, Al-Tai M, Ahmed IA, Kareem A, Baheer S, Sadik BM, Jafar MM, Alothman MS.   +7 more
europepmc   +1 more source

Screening for acid sphingomyelinase deficiency in patients with an interstitial lung disease. [PDF]

Orphanet J Rare Dis
Vermant M, Van Raemdonck I, Veyt N, Carlon MS, Cortesi EE, De Crem N, De Rooy M, Follet T, Gogaert S, Vanaudenaerde B, Cassiman D, De Sadeleer LJ, Wuyts WA.   +12 more
europepmc   +1 more source