Results 61 to 70 of about 23,449 (215)
Journal of Lipid Research, 2008 Sphingolipid biosynthesis and breakdown in yeast share many homologies in their pathways with higher eukaryotes (Dickson, R. C. 1998. Sphingolipid functions in Saccharomyces cerevisiae: comparison to mammals. Annu. Rev. Biochem. 67: 27–48).
Nabil Matmati, Yusuf A. Hannun
doaj +1 more source
A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet
The FEBS Journal, EarlyView.C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr +4 more
wiley +1 more source
Effect of saposins on acid sphingomyelinase [PDF]
Biochemical Journal, 1993 The effect of saposins (A, B, C and D) on acid sphingomyelinase activity was determined using a crude human kidney sphingomyelinase preparation and a purified sphingomyelinase preparation from human placenta. Saposin D stimulated the activity of the crude enzyme by increasing its apparent Km and Vmax. values for sphingomyelin hydrolysis.
M, Tayama +6 more
openaire +2 more sources
Journal of Fish Diseases, EarlyView.ABSTRACT Tenacibaculosis is an important disease of marine fishes caused by bacteria of the genus Tenacibaculum. Pathogenic Tenacibaculum species or serotypes, including Tenacibaculum maritimum, T. dicentrarchi, T. finnmarkense and T. soleae, have been isolated from farmed Chinook salmon (Oncorhynchus tshawytscha) during disease outbreaks in Aotearoa ...
Bjorn Böhmert +4 more
wiley +1 more source
Journal of Lipid Research, 2009 Electronegative LDL [LDL(−)] is an atherogenic subfraction of plasma LDL that has increased apolipoprotein E (apoE) and apoC-III content, high density, and increased susceptibility to aggregation.
Cristina Bancells +7 more
doaj +1 more source
Case report: The spectrum of SMPD1 pathogenic variants in Hungary
Frontiers in Genetics, 2023 Acid sphingomyelinase deficiency (ASMD) is an autosomal recessive disease caused by biallelic pathogenic variants in the sphingomyelin phosphodiesterase-1 (SMPD1) gene.
Maria Judit Molnar +8 more
doaj +1 more source
Photochemistry and Photobiology, EarlyView.Solar‐simulated light (SSL) promotes extracellular vesicle (EV) release from keratinocytes through a UVB‐driven, oxidative stress‐dependent pathway. SSL‐induced reactive oxygen species (ROS) generate oxidized glycerophosphocholines with PAF agonistic activity, which activate the Platelet‐activating factor receptor (PAFR), leading to acid ...
Divyanshu Aggarwal +3 more
wiley +1 more source
Saposin D: A sphingomyelinase activator [PDF]
Biochemical and Biophysical Research Communications, 1988 Saposin D, a newly discovered heat-stable, 10 kDa glycoprotein, was isolated from Gaucher spleen and purified to homogeneity. Chemical sequencing from its amino terminus demonstrated colinearity between its amino acid sequence and the deduced amino acid sequence of the fourth domain of prosaposin, the precursor of saposin proteins.
Morimoto, Satoshi +3 more
openaire +3 more sources
Acid sphingomyelinase serum activity in control and ICU patients.
, 2014 This figure indicates median pre- and post-operative acid sphingomyelinase serum activity of the control group and median acid sphingomyelinase serum activity of the ICU group on admission.
Supandi Winoto-Morbach (501243) +8 more
core +1 more source
Journal of Lipid Research, 2014 In hepatocytes, aging-associated decline in GSH has been linked to activation of neutral SMase (nSMase), accumulation of bioactive ceramide, and inflammation. In this study, we seek to test whether dietary supplementation with the cysteine precursor, L-2-
Gergana Deevska +5 more
doaj +1 more source