Results 161 to 170 of about 23,449 (215)

Glioblastoma Cells Expressing Oncogenic EGFR Release Multiple Extracellular Vesicle Subpopulations Positive or Negative for EGFR. [PDF]

open access: yesJ Extracell Biol
Pishavar E   +8 more
europepmc   +1 more source

A Retrospective Chart Review Study on the Burden of Illness of Acid Sphingomyelinase Deficiency in Brazil. [PDF]

open access: yesJ Clin Med
Giugliani R   +13 more
europepmc   +1 more source

Effects of Inhaled Amitriptyline on Airway Function and Immune Responses in Experimental Asthma. [PDF]

open access: yesAdv Respir Med
Michely A   +7 more
europepmc   +1 more source

Adults With Acid Sphingomyelinase Deficiency Have Sustained Improvements in Clinical Outcomes With up to 5 Years of Olipudase Alfa Enzyme Replacement Therapy: ASCEND Trial Final Results. [PDF]

open access: yesJ Inherit Metab Dis
Wasserstein MP   +20 more
europepmc   +1 more source

Inhibition of acid sphingomyelinase increases regulatory T cells in humans.

open access: yesBrain Communications, 2021
Genetic deficiency for acid sphingomyelinase or its pharmacological inhibition has been shown to increase Foxp3\(^+\) regulatory T-cell frequencies among CD4\(^+\) T cells in mice.
Jürgen Schneider-Schaulies   +2 more
exaly   +2 more sources

Acid Sphingomyelinase

2013
The enzyme acid sphingomyelinase catalyzes the hydrolysis of sphingomyelin to ceramide. The importance of the enzyme for cell functions was first recognized in Niemann-Pick disease type A and B, the genetic disorders with a massive accumulation of sphingomyelin in many organs. Studies in the last years demonstrated that the enzyme also has an important
Henry, Brian   +4 more
openaire   +3 more sources

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