Retraction notice to "A clinical pilot study for the detection of sphingomyelinase in leptospirosis patient's urine at tertiary care hospital" [Heliyon 9 (2023) e21138]. [PDF]
Ashaiba A +3 more
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Glioblastoma Cells Expressing Oncogenic EGFR Release Multiple Extracellular Vesicle Subpopulations Positive or Negative for EGFR. [PDF]
Pishavar E +8 more
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A genome-wide screen in <i>Pseudomonas aeruginosa</i> identifies genes impacting production of the hemolytic phospholipase C/sphingomyelinase, PlcH. [PDF]
Schutz K +5 more
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A Retrospective Chart Review Study on the Burden of Illness of Acid Sphingomyelinase Deficiency in Brazil. [PDF]
Giugliani R +13 more
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Effects of Inhaled Amitriptyline on Airway Function and Immune Responses in Experimental Asthma. [PDF]
Michely A +7 more
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A Preliminary Evaluation of Middle Ear Resonance Frequency via Wideband Tympanometry in Patients with Non-Alcoholic Fatty Liver Disease. [PDF]
Taştan M, Oral A, Yemiş T.
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Adults With Acid Sphingomyelinase Deficiency Have Sustained Improvements in Clinical Outcomes With up to 5 Years of Olipudase Alfa Enzyme Replacement Therapy: ASCEND Trial Final Results. [PDF]
Wasserstein MP +20 more
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Sphingolipid Metabolism: A Pathological Hub Linking Lipid Dysregulation and Chronic Inflammation in Atherosclerotic Cardiovascular Disease. [PDF]
Wang S, Dong Y, Li X, Dong R, Jing L.
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Inhibition of acid sphingomyelinase increases regulatory T cells in humans.
Genetic deficiency for acid sphingomyelinase or its pharmacological inhibition has been shown to increase Foxp3\(^+\) regulatory T-cell frequencies among CD4\(^+\) T cells in mice.
Jürgen Schneider-Schaulies +2 more
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The enzyme acid sphingomyelinase catalyzes the hydrolysis of sphingomyelin to ceramide. The importance of the enzyme for cell functions was first recognized in Niemann-Pick disease type A and B, the genetic disorders with a massive accumulation of sphingomyelin in many organs. Studies in the last years demonstrated that the enzyme also has an important
Henry, Brian +4 more
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