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A spectrophotometric method for determination of sphingomyelinase
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1978A colored derivative of sphingomyelin was synthesized and used as substrate for several sphingomyelinases. The compound is N-omega-trinitrophenyl-aminolaurylsphingosylphosphorylcholine. The rate of hydrolysis of this substrate was compared to that of bovine brain sphingomyelin, labelled with tritium in the choline moiety.
S, Gatt, T, Dinur, Y, Barenholz
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Sphingomyelinase of chicken erythrocyte membranes
Archives of Biochemistry and Biophysics, 1975Abstract Most of the chicken erythrocyte's sphingomyelin is hydrolyzed when the chicken red blood cells are incubated in hypotonie solution at 37 °C. Addition of detergents, such as Triton X-100 or Na-cholate, is essential for hydrolysis of external [3H ]sphingomyelin by the erythrocyte membranes.
D, Hirshfeld, A, Loyter
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Advances in lipid research, 1993
Although we have accumulated few data that would definitely designate the role of N-SMase in modern cell biology, current evidence indicates that N-SMase may play a central role in signal transduction (Fig. 7). Biomodulators such as hormones, antibiotics, drugs, growth factors, and lipoproteins may interact with N-SMase either directly or in ...
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Although we have accumulated few data that would definitely designate the role of N-SMase in modern cell biology, current evidence indicates that N-SMase may play a central role in signal transduction (Fig. 7). Biomodulators such as hormones, antibiotics, drugs, growth factors, and lipoproteins may interact with N-SMase either directly or in ...
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Roles and regulation of secretory and lysosomal acid sphingomyelinase
Cellular Signalling, 2009Russell William Jenkins +2 more
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Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair
Journal of Cell Biology, 2010Edward H Schuchman +2 more
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