Results 91 to 100 of about 4,752 (252)

6′-Amino-5,7-dibromo-2-oxo-3′-(trifluoromethyl)-1′H-spiro[indoline-3,4′-pyrano[2,3-c]pyrazole]-5′-carbonitrile

Molbank, 2021
The multicomponent reactions are environmentally benign synthetic methods of building-up of complex molecules and several levels of structural diversity for diverse applications.
Yuliya E. Ryzhkova, Varvara M. Kalashnikova, Michail N. Elinson   +2 more
doaj   +1 more source

Синтез і хімічні властивості конденсованих та спіросполучених похідних піролу [PDF]

, 2018
У дисертаційній роботі досліджено стереохімію та регіонаправленість фор-мування продуктів у процесах 1,3-диполярного циклоприєднання азометин-ілідів на основі ізатину та циклічних і аліфатичних α-амінокислот до похідних N-заміщених малеїнімідів ...
Павловська, Т.Л.
core  

Catalysis With Deep Eutectic Solvents: Challenges and Opportunities

ChemCatChem, Volume 17, Issue 11, June 6, 2025.
Deep eutectic solvents (DESs) are emerging as sustainable alternatives in catalysis, offering tunable properties for diverse chemical transformations. This review explores the dual role of DESs as solvents and catalysts, highlighting advancements in organic chemistry, materials science, CO2 fixation, biomass valorization, polymer degradation, and ...
Eduardo Guzmán
wiley   +1 more source

Ionic Liquids Immobilized on Magnetic Nanoparticles [PDF]

, 2017
Ionic liquids (ILs) immobilized on supports are among the most important derivatives of ILs. The immobilization process of ILs can transfer their desired properties to substrates.
Mokhtary, Masoud
core   +1 more source

From data to discovery: leveraging big data in plant natural products biosynthesis research

The Plant Journal, Volume 122, Issue 6, June 2025.
SUMMARY Plant natural products or specialized metabolites play a vital role in drug discovery and development, with many clinically important derivatives such as the anticancer drugs topotecan (derived from the natural alkaloid camptothecin) and etoposide (derived from the natural polyphenol podophyllotoxin).
Matthew McConnachie, Tuan‐Anh Minh Nguyen, Truc Kim, Trinh‐Don Nguyen, Thu‐Thuy T. Dang   +4 more
wiley   +1 more source

Computational Design, Synthesis, and Biological Assessment of Some Pyrrolo[3,4‐c]Pyrroles Targeting Mycobacterium Tuberculosis

ChemistrySelect, Volume 10, Issue 17, May 5, 2025.
A new set of spirooxindole‐ and spiroindenoquinoxaline‐derived pyrrolo[3,4‐c] pyrroles has been synthesized through atom‐economic one‐pot multicomponent reactions. Based on the results, compounds 4b and 5a demonstrated promising Glide scores and exhibited strong binding affinity with decaprenylphosphoryl‐β‐D‐ribofuranose oxidoreductase.
Mathiyazhagan Lavanya, Rajamanikandan Sundararaj, Kailasam Saravana Mani, Krishnakumar Balu, Mani Durai, Perwez Alam, Priya SD, Mathivanan Durai, Young Ho Ahn   +8 more
wiley   +1 more source

Recent Developments in the Synthesis of Chiral Compounds with Quaternary Centers by Organocatalytic Cascade Reactions [PDF]

, 2016
Quaternary carbon stereocenters are present in a wide variety of organic compounds and drug molecules. Highly enantioselective construction of such quaternary carbon stereocenters has received considerable attention owing to the great challenges in their
Ahrendt, Akiyama, Albertshofer, Albertshofer, Albrecht, Albrecht, Bartoli, Beeson, Bencivenni, Bencivenni, Bertelsen, Birrell, Brak, Burns, Büschleb, Cai, Chauhan, Chen, Chen, Das, Denmark, Du, Enders, Fogg, Halskov, Halskov, Hamilton, Hashimoto, Hawner, Hayashi, Hu, Huang, Iwabuchi, Jia, Jiang, Jiang, Jiang, Jones, Jones, Knowles, Lacour, Laforteza, Lan, Lefranc, Li, Liao, List, Liu, Loh, Lygo, Malerich, Manoni, McCooey, Melchiorre, Nicolaou, Okino, Ooi, Pellissier, Phipps, Qi, Rauniyar, Rendler, Romanov-Michailidis, Sanchez Duque, Shi, Shimizu, Sigman, Sigman, Silvi, Su, Sun, Sun, Tan, Tan, Tan, Tian, Tian, Tian, Tian, Tietze, Uraguchi, Vachal, Volla, Wang, Wei, Wenzel, Wu, Xie, Xu, Yang, Yeung, Yu, Zhang, Zhang, Zhang, Zhao, Zhao, Zhong, Zou   +98 more
core   +1 more source

Complete transfer of chirality in an intramolecular, thermal [2 + 2] cycloaddition of allene-ynes to form non-racemic spirooxindoles

Beilstein Journal of Organic Chemistry, 2011
A thermal [2 + 2] cycloaddition reaction of allene-ynes has been used to transform chiral non-racemic allenyl oxindoles into chiral non-racemic spirooxindoles containing an alkylidene cyclobutene moiety.
Kay M. Brummond, Joshua M. Osbourn
doaj   +1 more source

Dynamic Kinetic Asymmetric Transformation of Racemic Diastereomers: Diastereo- and Enantioconvergent Michael-Henry Reactions to Afford Spirooxindoles Bearing Furan-Fused Rings.

Angewandte Chemie, 2021
Dynamic kinetic asymmetric transformation (DYKAT) reactions of racemic diastereomer mixtures that afford the products as essentially single diastereomers with high enantioselectivities are described.
M. Sohail, F. Tanaka
semanticscholar   +1 more source

Recent Advancements in the Cyclization Strategies of 1,3‐Enynes Towards the Synthesis of Heterocyclic/Carbocyclic Frameworks

Chemistry – An Asian Journal, Volume 20, Issue 8, April 17, 2025.
In this review, the advancements in the cyclization of 1,3‐enynes to construct structurally diverse heterocyclic and carbocyclic frameworks are portrayed comprehensively. Divergent cyclization protocols along with mechanistic aspects for key transformations are also detailed. Abstract 1,3‐Enynes have demonstrated their utility as valuable precursors to
Akash P. Sakla, Shams Aaghaz, Shujauddin Ahmed, Naziya Neshat, Ahmed Kamal   +4 more
wiley   +1 more source