Results 101 to 110 of about 3,124 (225)
ChemInform Abstract: Multicomponent Reaction Discovery: Three‐Component Synthesis of Spirooxindoles. [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Corey R. J. Stephenson+3 more
openaire +4 more sources
A new asymmetric organocatalytic reaction to afford enantioenriched δ‐nitro alkene analogues and their synthetic manipulation are presented. The chiral nitro alkene was further used in a stereoselective cyclization reaction to afford an almost enantiomerically pure highly functionalised cyclopentane featuring five contiguous stereocenters.
Chiara Faverio+4 more
wiley +1 more source
Spirooxadiazoline oxindoles: synthesis and evaluation of anticancer and antimalarial activities [PDF]
Cancer is one of the modern world’s most common and deadly non-infectious disease. According to WHO Cancer Report of 2015, it is one of leading causes of morbidity and mortality worldwide with 8.8 million deaths in 2015 and it is expected to rise about ...
Lopes, Elizabeth de Abreu
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Abstract A domino SNAr‐ihDA/rDA reaction was developed from rarely exploited 3‐fluoro‐1,2,4‐triazines with bifunctional alkyne tethered nucleophiles to construct various fused non‐aromatic/heteroaromatic bicycles in yields ranging from 56 to 99%, notably within the family of valuable spirooxindole derivatives.
Anthony Lapray+5 more
wiley +1 more source
The role of allyl ammonium salts in palladium-catalyzed cascade reactions towards the synthesis of spiro-fused heterocycles [PDF]
There is a continuous need for designing new and improved synthetic methods aiming at minimizing reaction steps while increasing molecular complexity. In this respect, catalytic, one-pot cascade methodologies constitute an ideal tool for the construction
Beller, Matthias+4 more
core +1 more source
The synthesis of C3-carbocyclic spirooxindoles was realized by way of an intramolecular [2 + 2] cycloaddition reaction between a vinylidene indolin-2-one and an alkyne.
Kay M. Brummond, Joshua M. Osbourn
doaj +1 more source
Synthetic Methodologies Using Nucleophile-Electrophile Chemistry [PDF]
Synthetic organic chemistry is a vital part of the modern world – making up 15-20% of the U.S. economy. New synthetic reactions can lower manufacturing costs and create more environmentally friendly processes.
Hood, Jacob C.
core +1 more source
Синтез і хімічні властивості конденсованих та спіросполучених похідних піролу [PDF]
У дисертаційній роботі досліджено стереохімію та регіонаправленість фор-мування продуктів у процесах 1,3-диполярного циклоприєднання азометин-ілідів на основі ізатину та циклічних і аліфатичних α-амінокислот до похідних N-заміщених малеїнімідів ...
Павловська, Т.Л.
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Antibacterial spirooxindole alkaloids from Penicillium brefeldianum inhibit dimorphism of pathogenic smut fungi [PDF]
Huajun Shi+7 more
openalex +1 more source
The therapeutic potential of small molecules p53-MDM protein-protein interaction inhibitors [PDF]
Tese de mestrado, Ciências Biofarmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2016Ao longo dos anos, vários estudos científicos têm comprovado a importância da proteína supressora de tumor p53 na homeostase celular.
Nunes, Rute Cláudia Correia Sacadura
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