Results 51 to 60 of about 4,752 (252)
Synthesis and Diversification of Chiral Spirooxindoles via Organocatalytic Cascade Reactions
Chemistry Proceedings, 2023 The synthesis of chiral spirooxindoles through different amino catalytic activation modes is described herein. Several alkenylisatins were obtained from the Knoevenagel reaction of isatin and activated methylene derivatives containing electron ...
Jessica Navarro Vega +2 more
doaj +1 more source
Recent Advances in Green Approaches for Synthesis of Oxindole Derivatives [PDF]
, 2023 Oxindole derivatives are nitrogen-containing, five-membered heterocyclic molecules found in both natural and synthetic substances with diverse biological functions.
D.M.T.A.Samaradiwakara +2 more
core +2 more sources
Molecules, 2022 The [3+2] cycloaddition (32CA) reaction of an azomethine ylide (AY) with an electrophilic ethylene linked to triazole and ferrocene units has been studied within the Molecular Electron Density Theory (MEDT) at the ωB97X-D/6-311G(d,p) level.
Luis R. Domingo +2 more
doaj +1 more source
Enantioselective Synthesis of Spiro[indolizidine-1,3 '-oxindoles] [PDF]
, 2020 A three-step procedure for the enantioselective synthesis of spiro[indolizidine-1,3'-oxindoles], consisting of a stereoselective cyclocondensation reaction between (S)-tryptophanol and a prochiral or racemic 5-oxoester, bromination of the resulting ...
Amat Tusón, Mercedes +10 more
core +1 more source
Engaging Isatins in Multicomponent Reactions (MCRs) – Easy Access to Structural Diversity [PDF]
, 2021 Multicomponent reactions (MCRs) are a valuable tool in diversity-oriented synthesis. Its application to privileged structures is gaining relevance in the fields of organic and medicinal chemistry.
Brandão, Pedro +4 more
core +1 more source
Pharmaceutics, 2023 In this work, we first improved the aqueous solubility of biologically active spiro[cyclopropane-1,3′-oxindoles] (SCOs) via their complexation with different β-cyclodextrins (β-CDs) and proposed a possible mechanism of the complex formation.
Anna A. Kravtsova +5 more
doaj +1 more source
Photochemical aryl radical cyclizations to give (E)-3-Ylideneoxindoles [PDF]
, 2014 (E)-3-Ylideneoxindoles are prepared in methanol in reasonable to good yields, as adducts of photochemical 5-exo-trig of aryl radicals, in contrast to previously reported analogous radical cyclizations initiated by tris(trimethylsilyl)silane and azo ...
Aldabbagh, Fawaz +5 more
core +2 more sources
Studies on the Enantioselective Synthesis of E-Ethylidene-bearing Spiro[indolizidine-1,3′-oxindole] Alkaloids [PDF]
, 2021 A synthetic route for the enantioselective construction of the tetracyclic spiro[indolizidine-1,3'-oxindole] framework present in a large number of oxindole alkaloids, with a cis H-3/H-15 stereochemistry, a functionalized two-carbon substituent at C-15 ...
Amat Tusón, Mercedes +4 more
core +1 more source
Organocatalyzed Asymmetric Reaction Using α-Isothiocyanato Compounds [PDF]
, 2016 Organocatalyzed asymmetric reaction using α-isothiocyanato compounds has received much attention in the past 5 years, and significant progress has been made for three types of isothiocyanato compounds, including α-isothiocyanato amides, esters, and ...
Chen, Yong-Zheng +4 more
core +2 more sources
Recent Advances in Organocatalysis [PDF]
, 2021 Organocatalysis has recently attracted enormous attention as green and sustainable catalysis. It was realized as a fundamental field providing wide families of catalysts for important organic transformations.
core +1 more source