Results 51 to 60 of about 3,294 (234)

Efficient and green pathway for one-pot synthesis of spirooxindoles in the presence of CuO nanoparticles

open access: yesGreen Chemistry Letters and Reviews, 2017
In this research, a new, green and eco-friendly method for the synthesis of spirooxindole derivatives was presented. The reaction was performed at room temperature in the presence of catalytic amounts (4 mol.%) of CuO nanoparticles and products were ...
Leila Moradi, Zeynab Ataei
doaj   +1 more source

Recent Advances in Organocatalysis [PDF]

open access: yes, 2021
Organocatalysis has recently attracted enormous attention as green and sustainable catalysis. It was realized as a fundamental field providing wide families of catalysts for important organic transformations.

core   +1 more source

Metal-Free Diastereo- and Enantioselective Dearomative Formal [3 + 2] Cycloaddition of 2-Nitrobenzofurans and Isocyanoacetate Esters [PDF]

open access: yes, 2022
The diastereo- and enantioselective dearomative formal [3 + 2] cycloaddition of 2-nitrobenzofurans and α-aryl-α-isocyanoacetate esters provides tricyclic compounds bearing the 3a,8b-dihydro-1H-benzofuro[2,3-c]pyrrole framework with three consecutive ...
Blay Llinares, Gonzalo   +5 more
core   +3 more sources

Diversity-oriented synthesis as a tool for identifying new modulators of mitosis. [PDF]

open access: yes, 2014
The synthesis of diverse three-dimensional libraries has become of paramount importance for obtaining better leads for drug discovery. Such libraries are predicted to fare better than traditional compound collections in phenotypic screens and against ...
Alza, Esther   +8 more
core   +1 more source

Catalytic asymmetric synthesis of biologically important 3-hydroxyoxindoles: an update

open access: yesBeilstein Journal of Organic Chemistry, 2016
Oxindole scaffolds are prevalent in natural products and have been recognized as privileged substructures in new drug discovery. Several oxindole-containing compounds have advanced into clinical trials for the treatment of different diseases. Among these
Bin Yu   +3 more
doaj   +1 more source

The Synthesis of 3-Spirooxindole Derivatives. IV. The Conversion of 3-Spirooxindole to Indole Derivative.

open access: yesChemical and Pharmaceutical Bulletin, 1963
The conversion of 1-methylspiro (indoline-3, 1'-indolizine)-2-one to 12-methyl-1, 2, 3, 4, 6, 7, 12, 12b-octahydroindolo [2, 3-a] quinolizine is described as a preliminary for the chemical correlation of N-methylrhynchophyllane with N-methyldihydrocorynantheane.
T, OISHI, S, MAENO, Y, BAN
openaire   +3 more sources

Синтез і антимікробна активність гексаметилен-N-малеїнімідопохідних спіроіндол- 3,3’-піроло[3,4-с]піролу [PDF]

open access: yes, 2017
Aim. To synthesize a series of hexamethylene-N-maleinimidospiroindole-3,3’-pyrrolo[3,4-c]pyrrole derivatives, study the antimicrobial activity of the compounds synthesized and compare their antimicrobial activity with the antimicrobial activity of the ...
Filimonova, N. I.   +4 more
core   +2 more sources

Aza-Diels-Alder reaction of both electron-deficient azoalkenes with electron-deficient 3-phencaylideneoxindoles and 3-aryliminooxindol-2-ones

open access: yesGreen Synthesis and Catalysis, 2021
An uncommon aza-Diels-Alder reaction of electron-deficient azoalkenes and electron-deficient 3-phenacylideneoxindoles was successfully developed for convenient construction of the heterocyclic spirooxindoles.
Wenjing Shi, Jing Sun, Chao-Guo Yan
doaj   +1 more source

Iodide/H2O2 Catalyzed Intramolecular Oxidative Amination for the Synthesis of 3,2′-Pyrrolidinyl Spirooxindoles

open access: yesMolecules, 2018
An ammonium iodide/hydrogen peroxide-mediated intramolecular oxidative amination of 3-aminoalkyl-2-oxindoles was achieved, affording the corresponding 3,2′-pyrrolidinyl spirooxindoles and their 6- or 7-membered analogous in moderate to high yields.
Yu-Ting Gao   +6 more
doaj   +1 more source

Diastereoselective Formal 1,3-Dipolar Cycloaddition of Trifluoroethyl Amine-Derived Ketimines Enables the Desymmetrization of Cyclopentenediones

open access: yesMolecules, 2023
In this research, a metal-free diastereoselective formal 1,3-dipolar cycloaddition of N-2,2,2-trifluoroethylisatin ketimines and cyclopentene-1,3-diones which can efficiently lead to the desymmetrization of cyclopentene-1,3-diones is developed.
Lin-Qiang Li   +7 more
doaj   +1 more source

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