Results 51 to 60 of about 3,124 (225)

Pyrrolizine- and Indolizine-Derived Spirooxindoles: Synthesis, Antibacterial Activity and Inverse Docking Analysis

open access: goldChemistry
Spirooxindoles are a family of heterocyclic compounds which bear the oxindole nucleus in their structures, which have a considerable pharmaceutical potential and which have been linked to various drugs for the treatment of diverse diseases. In this work,
Pablo Romo   +6 more
openalex   +3 more sources

Organocatalyzed Asymmetric Reaction Using α-Isothiocyanato Compounds [PDF]

open access: yes, 2016
Organocatalyzed asymmetric reaction using α-isothiocyanato compounds has received much attention in the past 5 years, and significant progress has been made for three types of isothiocyanato compounds, including α-isothiocyanato amides, esters, and ...
Chen, Yong-Zheng   +4 more
core   +2 more sources

Recent Advances in Organocatalysis [PDF]

open access: yes, 2021
Organocatalysis has recently attracted enormous attention as green and sustainable catalysis. It was realized as a fundamental field providing wide families of catalysts for important organic transformations.

core   +1 more source

Синтез і антимікробна активність гексаметилен-N-малеїнімідопохідних спіроіндол- 3,3’-піроло[3,4-с]піролу [PDF]

open access: yes, 2017
Aim. To synthesize a series of hexamethylene-N-maleinimidospiroindole-3,3’-pyrrolo[3,4-c]pyrrole derivatives, study the antimicrobial activity of the compounds synthesized and compare their antimicrobial activity with the antimicrobial activity of the ...
Filimonova, N. I.   +4 more
core   +2 more sources

Iodide/H2O2 Catalyzed Intramolecular Oxidative Amination for the Synthesis of 3,2′-Pyrrolidinyl Spirooxindoles

open access: yesMolecules, 2018
An ammonium iodide/hydrogen peroxide-mediated intramolecular oxidative amination of 3-aminoalkyl-2-oxindoles was achieved, affording the corresponding 3,2′-pyrrolidinyl spirooxindoles and their 6- or 7-membered analogous in moderate to high yields.
Yu-Ting Gao   +6 more
doaj   +1 more source

Metal-Free Diastereo- and Enantioselective Dearomative Formal [3+2] Cycloaddition of 2-Nitrobenzofurans and Isocyanoacetate Esters [PDF]

open access: yes, 2022
[EN] The diastereo- and enantioselective dearomative formal [3 + 2] cycloaddition of 2-nitrobenzofurans and alpha-aryl-alpha isocyanoacetate esters provides tricyclic compounds bearing the 3a,8b-dihydro-1H-benzofuro[2,3-c]pyrrole framework with three ...
Blay, Gonzalo   +5 more
core   +4 more sources

One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with limited treatment options due to its heterogeneity and the lack of well-defined molecular targets.
Wagdy M. Eldehna   +5 more
doaj   +1 more source

A novel one-pot synthesis of spirooxindole derivatives catalyzed by nano ZnO

open access: diamondBulletin of the Chemical Society of Ethiopia, 2013
Nano zinc oxide was explored as a heterogeneous and reusable catalyst for the one-pot synthesis of spirooxindoles via three-component reaction between urea, isatin, and 1,3-dicarbonyl compounds.
Bita Baghernejad, Maliheh Khorshidi
openalex   +4 more sources

A synergetic effect of sonication with yolk-shell nanocatalyst for green synthesis of spirooxindoles

open access: yesGreen Chemistry Letters and Reviews, 2021
A synergetic effect of ultrasonic irradiation and yolk–shell nanocatalyst was examined for the synthesis of spirooxindoles from isatin, malononitrile and cyclohexanone.
Somaye Mohammadi, Hossein Naeimi
doaj   +1 more source

Sonochemical multi-component synthesis of spirooxindoles

open access: yesUltrasonics Sonochemistry, 2011
New and efficient multi-component methods have been developed for the synthesis of spirooxindoles in the presence of a catalytic amount of p-TSA as an inexpensive and available catalyst in EtOH under ultrasound irradiation. The method is simple, starts from readily accessible commercial starting materials, and provides biologically interesting products
Ayoob Bazgir   +3 more
openaire   +3 more sources

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