Results 71 to 80 of about 1,282 (170)

From Cells to Animals: Connexin43 Suppression Enhances Autophagic Flux to Restore Odontogenesis in Inflamed Dental Pulp

International Endodontic Journal, Volume 59, Issue 1, Page 134-152, January 2026.
ABSTRACT Aim Under certain conditions, infection‐induced inflammation may activate reparative processes to form a hard tissue barrier against microbial invasion. Autophagy participates in odontogenic differentiation during inflammation in vitro, but its role in pulp repair remains unclear.
Peiling Hu, Yingqing Chen, Ping Long, Anni Zhang, Xiaorong Lan, Yuanpei He, Guangwen Li, Shiting Li   +7 more
wiley   +1 more source

Terapia regenerativa endodóntica en el paciente adulto [PDF]

, 2018
Introducción: Los procedimientos regenerativos endodónticos son cada vez más utilizados y estudiados, indicándose principalmente para regenerar dientes inmaduros en niños y pacientes jóvenes. Sin embargo, se conocen casos de pacientes adultos con dientes
Travado Castillo, María del Pilar
core  

Functionalization of Photocrosslinkable GelMA Hydrogel With Metal Oxides for Direct Pulp Capping

BioMed Research International, Volume 2026, Issue 1, 2026.
Aim In this study, a photocrosslinkable methacrylated gelatin (GelMA) hydrogel, functionalized with metal oxide nanoparticles, was developed to support dentin regeneration in direct pulp capping applications. Magnesium (MgO), silicon (SiO2), strontium (SrO), and zinc (ZnO) were incorporated into GelMA at concentrations of 0.1%, 0.2%, 0.3%, 0.5%, and 1%
Ester Alves Ferreira Bordini, Ligia Espoliar Corrêa, Fernanda Balestrero Cassiano, Érika Soares Bronze-Uhle, Isabela Sanches Pompeo da Silva, Camila Correa da Silva Braga de Melo, Carlos Alberto de Souza Costa, Diana Gabriela Soares, Baisakhi Banerjee   +8 more
wiley   +1 more source

Conceptos actuales en el tratamiento de dientes jóvenes con necrosis pulpar [PDF]

, 2017
Los dientes permanentes con ápices inmaduros cuando sufren un traumatismo o caries y terminan con necrosis pulpar, resultan un gran desafío. La apexificación, ya sea inducida con hidróxido de calcio o con MTA, tiene como objetivo sellar el ápice y no ...
Regis, María Virginia
core  

Endodontic Management of Maxillary Central Incisors With Calcified Canal and Immature Apex Using Static Guide and Amniotic Membrane Plug

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
Traumatic dental injuries can affect the dental hard tissues, pulp, periodontium, alveolar bone, or gingiva, resulting in long‐term complications such as pulp canal obliteration and the cessation of root development. Such complications often defy conventional endodontic approaches.
Neelam Mittal, Swetha Burugupalli, Vijul, Shelly Sharma, Mohammad Faisal Azeez, Ayushi Kejriwal, Hannah Wesley   +6 more
wiley   +1 more source

Expanding Horizons: Next‐Generation and Interdisciplinary Advances in the Applications of Extracellular Vesicles

Journal of Extracellular Biology, Volume 4, Issue 12, December 2025.
ABSTRACT Extracellular vesicles (EVs) are increasingly recognized as universal mediators of communication in nature across all domains of life and as versatile tools with roles spanning a wide range of industries. Although EVs have been extensively studied in biomedicine, mainly in diagnostic and nanotherapy of cancer and neurodegenerative diseases ...
Esperanza González, Juan Manuel Falcón‐Pérez   +1 more
wiley   +1 more source

Harnessing Oxidized Alginate Microgels for Rapid and Self‐Assembling Dental Tissue Organogenesis In Vitro and In Vivo

Small Science, Volume 5, Issue 12, December 2025.
The system employs a high density human dental stem cells‐laden oxidized alginate‐based microgel with a "degrade‐to‐active" paradigm that mimics cellular condensation to enhance cell viability, achieve robust vascularization, and promote subsequent dental organogenesis, which is enabled by rapid degradation along with the elimination of residual ...
Chao Liang, Shuxuan Wu, Ziqi Huang, Zhenzhen Wu, Siyuan Chen, Feiming Li, Karrie Mei‐Yee Kiang, Gilberto Ka‐Kit Leung, Indong Jun, Hwan D. Kim, Ann‐Na Cho, Hee Jung Lee, Honghyun Park, Yiu Yan Leung, Seong Jun Kim, Seil Sohn, Haram Nah, Jae Seo Lee, Il Keun Kwon, Dong‐Nyoung Heo, Sang‐woo Lee, Zhaoming Wu, Sang Jin Lee   +22 more
wiley   +1 more source

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, Volume 12, Issue 44, November 27, 2025.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

Las células madre dentales y su aplicación en odontología. [PDF]

, 2020
Recent advances in tissue engineering and regenerative medicine offer a long-term solution through biological repair, replacement of damaged teeth or maintenance and improvement of tissue and organ function through the use of stem cells.
Arbildo-Vega, Heber, Cruzado-Oliva, Fredy, Infantes-Ruiz, Edward   +2 more
core   +1 more source

DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013

Stem Cell Research & Therapy, 2020
Background Mesenchymal stem cell (MSC)-based cartilage tissue regeneration is a treatment with great potential. How to enhance the MSC chondrogenic differentiation is a key issue involved in cartilage formation.
Haoqing Yang, Yangyang Cao, Jianpeng Zhang, Yuncun Liang, Xiaomin Su, Chen Zhang, Huina Liu, Xiao Han, Lihua Ge, Zhipeng Fan   +9 more
doaj   +1 more source