Results 81 to 90 of about 1,282 (170)

Effect of diode low level laser and red light emitting diode irradiation on cell proliferation and osteogenic/odontogenic differentiation of stem cells from the apical papilla

BMC Oral Health, 2022
Background This experimental study aimed to assess the effect of irradiation of red light-emitting diode (LED) and Diode low-level laser (LLL) on osteogenic/odontogenic differentiation of stem cells from the apical papilla (SCAPs).
Afsaneh Rahmati, Roshanak Abbasi, Rezvan Najafi, Loghman Rezaei-soufi, Hamed Karkehabadi   +4 more
doaj   +1 more source

LPS‐Induced Mitochondrial Damage via SLC41A1‐Mediated Magnesium Ion Efflux Leads to the Pyroptosis of Dental Stem Cells

Advanced Science, Volume 12, Issue 42, November 13, 2025.
Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu, Chenyu Song, Liyuan Zhang, Xue Han, Chaoyuan Li, Yanhong Yan, Ludan Xing, Mengting Si, Bo Yang, Lingyuan Cheng, Akimi Muramatsu, Beizhan Jiang   +11 more
wiley   +1 more source

Comparative Secretome Analysis of Mesenchymal Stem Cells From Dental Apical Papilla and Bone Marrow During Early Odonto/Osteogenic Differentiation: Potential Role of Transforming Growth Factor-β2

Frontiers in Physiology, 2020
To understand the functions of secretory proteins in odontogenesis and to further the understanding of the different molecular events during odontogenesis and osteogenesis, we induced the odonto/osteogenic differentiation of stem cells from dental apical
Shi Yu, Jingzhi Li, Yuming Zhao, Xiaoxia Li, Lihong Ge   +4 more
doaj   +1 more source

In Vitro Free Implantation of Stem Cells from Apical Papilla Using Injectable Hydrogel‐Laden 3D‐Printed Scaffold to Enhance Tissue Organization and Vascular Infiltration In Vivo

Advanced NanoBiomed Research, Volume 5, Issue 11, November 2025.
This study explores CMCTS/oHA‐encapsulated high‐density stem cells from the apical papilla‐modified 3D‐printed PMMA composite scaffolds as a novel tissue engineering strategy. The hydrogel demonstrates excellent injectability and degradation, enhancing cell inoculation efficiency.
Ziqi Huang, Chao Liang, Zhenzhen Wu, Siyuan Chen, Feiming Li, Kiho Cho, Woo‐Youl Maeng, Yeon‐Hee Lee, Su A. Park, Yeong‐Jin Choi, Hui‐suk Yun, Soo‐Hong Lee, Donghyun Lee, Sang‐Hyun An, Jae Beum Bang, Sang Jin Lee   +15 more
wiley   +1 more source

Notch2 is involved in regulating apical tissue repair following severe intrusive luxation [PDF]

Journal of Applied Oral Science
This study aims to characterize apical repair dynamics in immature permanent teeth after severe intrusive luxation, and to explore Notch signaling pathway regulation in this process using a Sprague-Dawley rat model.
Yuanpei He, Xuyan Gong, Cancan Ding, Yang Qiu, Guangwen Li, Shiting Li   +5 more
doaj   +2 more sources

Regenerative Endodontic Treatment in an Immature Permanent Tooth With Necrotic Pulp and Periradicular Lesion

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Managing necrotic immature permanent teeth with an open apex presents a treatment challenge. Regenerative endodontic procedures have emerged as biologically based approaches for these cases, suggesting an alternative to conventional apexification. This report describes successful revascularization of an immature mandibular second premolar with
Mamak Adel, Zohreh Asgari
wiley   +1 more source

Assessing the Cytotoxic Effects of Calcium Hydroxide and Triple Antibiotic Paste on SCAP: A Systematic Review [PDF]

Aim: This systematic review paper focuses on the effects of two common intracanal medicaments used in regenerative endodontic procedures on the survival of human apical papilla cells.Background: Periapical lesions form due to an inflammatory response ...
Anukriti Kumari, Jyotsana Singh, Neetu Jhunjhunwala, P.Nihar, Ritik Kashwani, Sooriaprakas Chandrasekaran   +5 more
core   +2 more sources

Microbial Loads in Traumatized Immature Teeth and Their Impact on the Treatment Outcomes of Regenerative Endodontic Treatment: A Randomized Clinical Trial Comparing Chlorhexidine and Calcium Hydroxide

Dental Traumatology, Volume 41, Issue 5, Page 501-515, October 2025.
ABSTRACT Introduction Regenerative endodontic treatment (RET) aims to promote root maturation in necrotic immature teeth, where effective microbial disinfection is crucial for treatment success. This study evaluated the effect of calcium hydroxide (CH) and 2% chlorhexidine gluconate (CHD) as intracanal medicaments and their impact on bacterial loads ...
Alina Wikström, Olena Rakhimova, Pavel Călin, Georgios Tsilingaridis, Malin Brundin, Nelly Romani Vestman   +5 more
wiley   +1 more source

3D culture inhibits replicative senescence of SCAPs via UQCRC2-mediated mitochondrial oxidative phosphorylation

Journal of Translational Medicine
Stem cells derived from the apical papilla (SCAPs) play a crucial role in tooth root development and dental pulp regeneration. They are important seed cells for bone/tooth tissue engineering.
Yijia Shi, Tong Xiao, Yingying Weng, Ya Xiao, Jintao Wu, Jing Wang, Wenmin Wang, Maoshen Yan, Ming Yan, Zehan Li, Jinhua Yu   +10 more
doaj   +1 more source

Study on the promotion of osteo/odontogenic differentiation on SCAPs and anti-inflammatory effects of EGCG/CeO2-loaded nanoparticles in an inflammatory microenvironment [PDF]

Kouqiang yixue
Objective To investigate the effects of composite nanoparticles E/Ce@MCSNs loaded with epigallocatechin-3-gallate (EGCG) and cerium dioxide (CeO2) on the odonto/osteogenic differentiation of human stem cells from the apical papilla (SCAPs) and macrophage
WU Yuting, DAI Mingrui, LENG Diya, ZHU Tingting, WU Tao, WU Daming
doaj   +1 more source