Results 31 to 40 of about 111,091 (294)

Analisis Manajemen Sumber Daya Manusia Strategik dalam Upaya Meningkatkan Kinerja Pegawai di Kantor Pengadilan Agama Sumenep

open access: yesJurnal Pamator, 2021
The Sumenep ”Religion Court requires Strategic human resources management  to achieve its goals. Strategic HRM considers the agency strategy implications of the entire human resource system within the agency by translating agency objectives into specific
Dewy Arifah
doaj   +1 more source

The impact of strategic human resources planning on the organizational performance of public shareholding companies in Jordan [PDF]

open access: yesProblems and Perspectives in Management, 2020
Performance management (PM) is a common practice used by organizations to assess and manage employees’ work. Much of PM research is closely related to management practices.
Shaker Al-Qudah   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Digital Transformation and its role in supporting Strategic Human Resources Management (An Applied Study on Egyptian Commercial Banks) [PDF]

open access: yesالمجلة العلمية للبحوث التجارية - جامعة المنوفية
This study aimed to identify Digital Transformation and its role in supporting Strategic Human Resources Management, and to achieve the goal of the study, a questionnaire was designed and distributed to the study sample of 399 items.
Aly Makhareta   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The effect of strategic human resources management (SHRM) on organizational excellence [PDF]

open access: yesProblems and Perspectives in Management, 2020
Human resources at different levels are the executives of organizational tasks toward excellence. Missing the track of human resources will leave the organization behind.
Mohamad Noor Al-Jedaiah   +1 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Studying the Impact of Strategic Human Resource Management on Financial Performance of Companies Listed on Tehran Stock Exchange [PDF]

open access: yesراهبرد مدیریت مالی, 2014
Within the challenging environment of the new millennium and competition among organizations and companies, one of the factors enhancing success for organizations is to focus on strategic human resource management.
Reza Rasouli   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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