Results 31 to 40 of about 7,278,692 (246)

RNA tertiary structure modeling with BRiQ potential in CASP15

, 2023
We describe the modeling method for RNA tertiary structures employed by team AIchemy_RNA2 in the 15th Critical Assessment of Structure Prediction (CASP15). The method consists of the following steps.
Chen, K, Yaoqi Zhou, Xiong, P, Sheng Wang, Ke Chen, Zhou, Y, Wang, S, Peng Xiong   +7 more
core   +1 more source

Current Clinical and Pre-Clinical Imaging Approaches to Study the Cancer-Associated Immune System

Frontiers in Immunology, 2021
In the light of the success and the expected growth of its arsenal, immuno-therapy may become the standard neoadjuvant procedure for many cancers in the near future.
Christopher G. Mueller, Christian Gaiddon, Aïna Venkatasamy, Aïna Venkatasamy   +3 more
doaj   +1 more source

LLT1-CD161 Interaction in Cancer: Promises and Challenges

Frontiers in Immunology, 2022
The success of immune checkpoint therapy in cancer has changed our way of thinking, promoting the design of future cancer treatments that places the immune system at the center stage.
Veronique M. Braud, Aïda Meghraoui-Kheddar, Roxane Elaldi, Luciana Petti, Claire Germain, Fabienne Anjuère   +5 more
doaj   +1 more source

Tertiary lymphoid structures are critical for cancer prognosis and therapeutic response

Frontiers in Immunology, 2023
Tertiary lymphoid structures (TLSs) are ectopic lymphocyte aggregates that form at sites of chronic inflammation, including cancers, in non-lymphoid tissues.
Qianqian Zhang, Suhui Wu
doaj   +1 more source

Reliability of tumor-infiltrating lymphocyte and tertiary lymphoid structure assessment in human breast cancer

, 2017
The presence of tumor-infiltrating lymphocytes (TIL), reflecting host immune activity, is frequently correlated with better clinical outcomes, particularly in HER2-positive and triple-negative breast cancer.
Decaestecker C., Fornili M., De Wind A., Buisseret L., Larsimont D., Piccart-Gebhart M., Biganzoli E., Desmedt C., Wang X., Duquenne S., Garaud S., Naveaux C., Rorive S., Rothe F., Boisson A., Sotiriou C., Willard-Gallo K., Van Den Eyden G.   +17 more
core   +2 more sources

Tertiary lymphoid structures as local perpetuators of organ-specific immune injury: implication for lupus nephritis

Frontiers in Immunology, 2023
In response to inflammatory stimuli in conditions such as autoimmune disorders, infections and cancers, immune cells organize in nonlymphoid tissues, which resemble secondary lymphoid organs.
Meiying Wang, Meiying Wang, Meiying Wang, Snehin Rajkumar, Yupeng Lai, Xingjiao Liu, Jing He, Jing He, Tatsuya Ishikawa, Dhiraj Nallapothula, Ram Raj Singh, Ram Raj Singh, Ram Raj Singh, Ram Raj Singh   +13 more
doaj   +1 more source

Putative Immunological Functions of Inducible Skin-Associated Lymphoid Tissue in the Context of Mucosa-Associated Lymphoid Tissue

Frontiers in Immunology, 2021
Acquired immunity is orchestrated in various lymphoid organs, including bone marrow, thymus, spleen, and lymph nodes in humans. However, mucosa-associated lymphoid tissue (MALT) is evolutionally known to be emerged in the oldest vertebrates as an ...
Toshiaki Kogame, Kenji Kabashima, Gyohei Egawa   +2 more
doaj   +1 more source

Tertiary Lymphoid Structures:Autoimmunity Goes Local [PDF]

, 2018
Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune diseases. TLS present features of secondary lymphoid organs such as segregated T and B cell zones, presence of follicular dendritic cell networks, high endothelial ...
Smith C., Pipi, Elena, David H. Gardner, Saba Nayar, Barone, Francesca; id_orcid, Nayar, Saba, Gardner D. H., Francesca Barone, Gardner, David H, Colafrancesco, Serena, Serena Colafrancesco, Pipi E., Smith, Charlotte, Charlotte Smith, Colafrancesco S., Barone F., Nayar S., Elena Pipi   +17 more
core   +1 more source

Mesenchymal stem cells and T cells in the formation of Tertiary Lymphoid Structures in Lupus Nephritis [PDF]

, 2018
Tertiary lymphoid structures (TLS) develop in the kidneys of lupus-prone mice and systemic lupus erythematosus (SLE) patients with lupus nephritis (LN).
Fenton, Kristin Andreassen, Aud-Malin K. Hovd, Kristin A. Fenton, Dorraji, Seyed Esmaeil, Kanapathippillai, Premasany, Gunnstein Bakland, Eilertsen, Gro Østli, Stine L. Figenschau, S. Esmaeil Dorraji, Figenschau, Stine, Premasany Kanapathippillai, Gro Østli Eilertsen, Bakland, Gunnstein, Hovd, Aud-Malin Karlsson   +13 more
core   +1 more source

Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer

OncoImmunology, 2020
Tertiary lymphoid structures (TLSs), clusters of immune cells found around tumor tissue, have been shown to be associated with anti-tumor immunity, but the cellular composition within each TLS and whether the cellular composition of a TLS affects a ...
Kyoko Yamaguchi, Mamoru Ito, Hirofumi Ohmura, Fumiyasu Hanamura, Michitaka Nakano, Kenji Tsuchihashi, Shuntaro Nagai, Hiroshi Ariyama, Hitoshi Kusaba, Hidetaka Yamamoto, Yoshinao Oda, Masafumi Nakamura, Koichi Akashi, Eishi Baba   +13 more
doaj   +1 more source