Results 31 to 40 of about 11,902 (192)

Characterisation and prognostic value of tertiary lymphoid structures in oral squamous cell carcinoma [PDF]

, 2014
Background -Oral squamous cell carcinomas are often heavily infiltrated by immune cells. The organization of B-cells, follicular dendritic cells, T-cells and high-endothelial venules into structures termed tertiary lymphoid structures have been detected ...
Wirsing, Anna Maria, Oddveig G Rikardsen, Anna M Wirsing, Sonja E Steigen, Hadler-Olsen, Elin Synnøve, Elin Hadler-Olsen, Steigen, Sonja Eriksson, Uhlin-Hansen, Lars, Rikardsen, Oddveig G, Lars Uhlin-Hansen   +9 more
core   +1 more source

Kidney tertiary lymphoid structures in Lupus Nephritis develop into large interconnected networks and resemble lymph nodes in gene signature [PDF]

, 2020
Immune aggregates organized as tertiary lymphoid structures (TLS) are observed within the kidneys of patients with systemic lupus erythematosus and lupus nephritis (LN).
Figenschau, Stine, Thiyagarajan, Dhivya Borra, Fenton, Kristin Andreassen, Horvei, Kjersti Daae, Dorraji, Seyed Esmaeil, Kanapathippillai, Premasany, Fenton, Christopher Graham, Ursvik, anita, Stenersrød, Mikael Ryan, Pedersen, Hege Lynum, Hovd, Aud-Malin Karlsson   +10 more
core   +1 more source

Tertiary Lymphoid Structures: Autoimmunity Goes Local [PDF]

Frontiers in Immunology, 2018
Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune diseases. TLS present features of secondary lymphoid organs such as segregated T and B cell zones, presence of follicular dendritic cell networks, high endothelial venules and specialized lymphoid fibroblasts and display the mechanisms to support local adaptive ...
Elena Pipi, Elena Pipi, Saba Nayar, David H. Gardner, Serena Colafrancesco, Charlotte Smith, Francesca Barone   +6 more
openaire   +4 more sources

Close Association between Altered Urine–Urothelium Barrier and Tertiary Lymphoid Structure Formation in the Renal Pelvis during Nephritis [PDF]

, 2022
BACKGROUND: Kidneys with chronic inflammation develop tertiary lymphoid structures (TLSs). Infectious pyelonephritis is characterized by renal pelvis (RP) inflammation.
Teppei Nakamura, Taro Horino, Nakamura, Teppei, Horino, Taro, Ali, Elewa Yaser Hosny, Masum, Md. Abdul, Namba, Takashi, Marina Hosotani, Elewa Yaser Hosny Ali, Hosotani, Marina, Md. Abdul Masum, Yuki Otani, Osamu Ichii, Takashi Namba, Yasuhiro Kon, Kon, Yasuhiro, Ichii, Osamu, Hosny Ali, Elewa Yaser, Otani, Yuki   +18 more
core   +1 more source

Reliability of tumor-infiltrating lymphocyte and tertiary lymphoid structure assessment in human breast cancer.

, 2017
The presence of tumor-infiltrating lymphocytes (TIL), reflecting host immune activity, is frequently correlated with better clinical outcomes, particularly in HER2-positive and triple-negative breast cancer.
Sotiriou, Christos, Alexandre de Wind, Francoise Rothé, Marco Fornili, Sandrine Rorive, Wang, Xiaoxiao, Elia Biganzoli, A. Boisson, D. Larsimont, Celine Naveaux, Christine Desmedt, Desmedt, Christine, S. Duquenne, Martine Piccart-Gebhart, Laurence Buisseret, Anais Boisson, Boisson, Anaïs, X. Wang, G. Van Den Eyden, S. Rorive, K. Willard-Gallo, A. De Wind, Naveaux, Céline, Fornili, Marco, Van den Eyden, Gert, Rothé, Françoise, Biganzoli, Elia, Christos Sotiriou, F. Rothé, Larsimont, Denis, Decaestecker, Christine, Duquenne, S, E. Biganzoli, Soizic Garaud, Piccart-Gebhart, Martine, Denis Larsimont, Karen Willard-Gallo, Xiaoxiao Wang, Buisseret, Laurence, Garaud, Soizic, Gert Van den Eyden, L. Buisseret, Christine Decaestecker, Rorive, Sandrine, S. Garaud, C. Sotiriou, M. Fornili, de Wind, Alexandre, Willard-Gallo, Karen, C. Naveaux, Sebastien Duquenne, C. Decaestecker, C. Desmedt, M. Piccart-Gebhart   +53 more
core   +2 more sources

Characteristics of tertiary lymphoid structures in primary cancers [PDF]

OncoImmunology, 2013
Tumors are sustained by complex networks of interactions between malignant cells, stromal cells and tumor-infiltrating immune cells. These networks differ from patient to patient in terms of nature, composition and organization as well as with regard to the precise localization of tumor-infiltrating cells.
Goc, Jérémy, Fridman, Wolf-Herman, Sautès-Fridman, Catherine, Dieu-Nosjean, Marie-Caroline   +3 more
openaire   +2 more sources

Tertiary lymphoid structures are critical for cancer prognosis and therapeutic response

Frontiers in Immunology, 2023
Tertiary lymphoid structures (TLSs) are ectopic lymphocyte aggregates that form at sites of chronic inflammation, including cancers, in non-lymphoid tissues.
Qianqian Zhang, Suhui Wu
doaj   +1 more source

sj-docx-1-jdr-10.1177_00220345231151685 – Supplemental material for Tertiary Lymphoid Structure Raises Survival and Immunotherapy in HPV− HNSCC

, 2023
Supplemental material, sj-docx-1-jdr-10.1177_00220345231151685 for Tertiary Lymphoid Structure Raises Survival and Immunotherapy in HPV− HNSCC by H. Li, S.-W. Zhu, J.-J. Zhou, D.-R. Chen, J. Liu, Z.-Z. Wu, W.-Y. Wang, M.-J. Zhang and Z.-J. Sun in Journal
S.-W. Zhu (14763529), D.-R. Chen (14763535), J.-J. Zhou (14763532), J. Liu (797642), Z.-Z. Wu (14763538), M.-J. Zhang (14763544), H. Li (1597072), W.-Y. Wang (14763541), Z.-J. Sun (14763547)   +8 more
core   +1 more source

Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development [PDF]

, 2018
Tertiary lymphoid structures (TLSs) display phenotypic and functional characteristics of secondary lymphoid organs, and often develop in tissues affected by chronic inflammation, as well as in certain inflammation-associated cancers where they are ...
Yu, L, Gallimore, A, Ferrero, RL, Jones, GW, Bhathal, PS, Oshima, M, Hill, DG, Gao, H, Sievert, W, McLeod, L, Jenkins, BJ, Balic, JJ, D'Costa, K, Oshima, H, West, A   +14 more
core   +2 more sources

Tertiary lymphoid structures as local perpetuators of organ-specific immune injury: implication for lupus nephritis

Frontiers in Immunology, 2023
In response to inflammatory stimuli in conditions such as autoimmune disorders, infections and cancers, immune cells organize in nonlymphoid tissues, which resemble secondary lymphoid organs.
Meiying Wang, Meiying Wang, Meiying Wang, Snehin Rajkumar, Yupeng Lai, Xingjiao Liu, Jing He, Jing He, Tatsuya Ishikawa, Dhiraj Nallapothula, Ram Raj Singh, Ram Raj Singh, Ram Raj Singh, Ram Raj Singh   +13 more
doaj   +1 more source