Results 51 to 60 of about 25,496 (206)

Mechanisms of tertiary lymphoid structure formation: cooperation between inflammation and antigenicity

Frontiers in Immunology, 2023
To mount an effective anti-tumor immune response capable of controlling or eliminating disease, sufficient numbers of lymphocytes must be recruited to malignant tissue and allowed to sustain their effector functions.
Shrijan Khanal, Andreas Wieland, Andrew J. Gunderson   +2 more
doaj   +1 more source

Early IL-1 signaling promotes iBALT induction after influenza virus infection [PDF]

, 2016
Inducible bronchus-associated lymphoid tissue (iBALT) is a long lasting tertiary lymphoid tissue that can be induced following influenza A virus (IAV) infection.
Deswarte, K. (Kim), Geurts van Kessel, C.H. (Corine), Hammad, H. (Hamida), Lambrecht, B.N.M. (Bart), Neyt, K. (Katrijn)   +4 more
core   +5 more sources

Tertiary lymphoid structures in autoimmune diseases

Frontiers in Immunology
Tertiary lymphoid structures (TLSs) are organized lymphoid-like aggregations in non-lymphoid tissues. Tissues with chronic and persistent inflammation infiltration may drive and form ectopic germinal center-like structures, which are very common in autoimmune diseases, chronic infections, and tumor microenvironments.
Yuanji Dong, Ting Wang, Huaxiang Wu
openaire   +3 more sources

Control of Dichotomic Innate and Adaptive Immune Responses by Artery Tertiary Lymphoid Organs in Atherosclerosis [PDF]

, 2012
Tertiary lymphoid organs (TLOs) emerge in tissues in response to non-resolving inflammation such as chronic infection, graft rejection, and autoimmune disease.
Andreas Johann Habenicht, Desheng eHu, Desheng eHu, Falk eWeih, Michael eBeer, Rolf eGräbner   +5 more
core   +2 more sources

Epigenetic memory in induced pluripotent stem cells. [PDF]

, 2010
Somatic cell nuclear transfer and transcription-factor-based reprogramming revert adult cells to an embryonic state, and yield pluripotent stem cells that can generate all tissues.
Aryee, MJ, Cahan, P, Cunniff, KC, Daley, GQ, Doi, A, Ehrlich, LIR, Feinberg, AP, Hanna, J, Hongguang, H, Irizarry, RA, Jaenisch, R, Ji, H, Jung, N, Kim, J, Kim, K, McKinney-Freeman, S, Murakami, P, Naveiras, O, Ng, K, Orkin, SH, Seita, J, Takeuchi, A, Weissleder, R, Weissman, IL, Wen, B, Yabuuchi, A, Yoon, TJ, Zhao, R   +27 more
core   +5 more sources

Molecular and spatial analysis of tertiary lymphoid structures in Sjogren’s syndrome

Nature Communications
Tertiary lymphoid structures play important roles in autoimmune and non-autoimmune conditions. While many of the molecular mechanisms involved in tertiary lymphoid structure formation have been identified, the cellular sources and temporal and spatial ...
Saba Nayar, Jason D. Turner, Saba Asam, Eanna Fennell, Matthew Pugh, Serena Colafrancesco, Onorina Berardicurti, Charlotte G. Smith, Joe Flint, Ana Teodosio, Valentina Iannizzotto, David H. Gardner, Joel van Roon, Ilya Korsunsky, Dawn Howdle, Roche Fibroblast Network Consortium, Andreas P. Frei, Kara G. Lassen, Simon J. Bowman, Wan-Fai Ng, Adam P. Croft, Andrew Filer, Benjamin A. Fisher, Christopher D. Buckley, Francesca Barone   +24 more
doaj   +1 more source

Regulation Of Tertiary Lymphoid Structure Formation In Periodontitis

International Dental Journal
Aim or purpose: This study investigates the role of gingival fibroblasts in the formation of tertiary lymphoid structures (TLSs) in periodontitis and their impact on inflammation.
Jiawei Lu, Zehui Xiong, Jinyi Zhang, Lijun Luo, Xiao Wu   +4 more
doaj   +1 more source

Dendritic cells and oral transmission of prion diseases [PDF]

, 2004
Transmissible spongiform encephalopathies (scrapie, BSE, Kuru) develop as central nervous system (CNS) diseases after long incubation periods, and many of which may arise following the consumption of infected material.
Huang, FP, MacPherson, GG
core   +1 more source

Rare Variants of Putative Candidate Genes Associated With Sporadic Meniere's Disease in East Asian Population [PDF]

, 2020
Objectives: The cause of Meniere's disease (MD) is unclear but likely involves genetic and environmental factors. The aim of this study was to investigate the genetic basis underlying MD by screening putative candidate genes for MD.
Arweiler-Harbeck, Begovich, Brama, Cabrera, Campbell, de Lima, Doi, Dong, Eichler, Filipo, Flook, Foster, Frejo, Frejo, Frejo, Furuta, Gallego-Martinez, Gazquez, Gazquez, Girirajan, Greco, Hietikko, Huang, Kawaguchi, Khorsandi, Kim, Kimura, Klar, Koo, Lee, Lee, Lee, Lee, Lettre, Li, Li, Lien, Lien, Liew, Lopez-Escamez, Lopez-Escamez, Lopez-Escamez, Lopez-Escamez, Marcus, Martín-Sierra, Martín-Sierra, Melchiorri, Meng, Morrison, Mustelin, Nair, Nair, Nair, Nishio, Oliveira-Paula, Qin, Rasheed, Rauch, Recupero, Reich, Rentzsch, Requena, Requena, Requena, Requena, Roman-Naranjo, Saint Pierre, Schwanitz, Shu, Sun, Takumida, Teggi, Teggi, Teggi, Teranishi, Tilburg, Tomoda, Uchida, Vrabec, Yang, Yazdani, Yazdani   +81 more
core   +1 more source

Tertiary lymphoid structures in ovarian cancer

Frontiers in Immunology
Ovarian cancer (OC) is a significant cause of cancer-related mortality in women worldwide. Despite advances in treatment modalities, including surgery and chemotherapy, the overall prognosis for OC patients remains poor, particularly for patients with advanced or recurrent disease.
Guojuan Sun, Yi Liu
openaire   +3 more sources