Results 111 to 120 of about 5,610 (204)

Tertiary lymphoid structures in colorectal cancer

Annals of Medicine
Background Tertiary lymphoid structures (TLS) are ectopic clusters of immune cells found in non-lymphoid tissues, particularly within the tumor microenvironment (TME).
Jianyu Lv, Xiuyu Zhang, Mi Zhou, Junbin Yan, Guanqun Chao, Shuo Zhang   +5 more
doaj   +1 more source

Single-Cell Analysis Provides New Insights into the Roles of Tertiary Lymphoid Structures and Immune Cell Infiltration in Kidney Injury and Chronic Kidney Disease [PDF]

Chronic kidney disease (CKD) is a global health concern with high morbidity and mortality. Acute kidney injury (AKI) is a pivotal risk factor for the progression of CKD, and the rate of AKI-to-CKD progression increases with aging. Intrarenal inflammation
Yanagita, Motoko, Yoshikawa, Takahisa
core   +1 more source

Hitchhiker's guide to cancer-associated lymphoid aggregates in histology images: manual and deep learning-based quantification approaches

Quantification of lymphoid aggregates including tertiary lymphoid structures with germinal centers in histology images of cancer is a promising approach for developing prognostic and predictive tissue biomarkers.
Ciompi, Francesco, Silina, Karina
core  

Roles and functions of tumor-infiltrating lymphocytes and tertiary lymphoid structures in gastric cancer progression

Frontiers in Immunology
Gastric cancer (GC), a leading cause of cancer mortality, exhibits profound molecular heterogeneity and immunosuppressive tumor microenvironment (TME) features that limit therapeutic efficacy.
Zhiyuan Yao, Gengchen Li, Di Pan, Zichen Pei, Yan Fang, Haonan Liu, Zhengxiang Han   +6 more
doaj   +1 more source

Analyses of germinal center B cells and tertiary lymphoid structures (TLS) in mouse and human HNSCC

Laryngo-Rhino-Otologie, 2019
M Sonntag, C Brunner, TK Hoffmann
openaire   +1 more source

606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy

Regular and Young Investigator Award Abstracts, 2023
Robert Johnston, Hartmut Koeppen, Roy S Herbst, Kurt Schalper, Filippo De Marinis, Giuseppe Giaccone, Jacek Jassem, Marcus Ballinger, Barani Kumar Rajendran, David R Spigel, Miguel López de Rodas, Minu K Srivastava, Jennifer M Giltnane, Barzin Y Nabet, David S Shames, Velimir Gayevskiy, Vy Ma, Ivette Estay, Tien Hoang, Reena Amin   +19 more
openaire   +2 more sources

Guards at the gate: physiological and pathological roles of tissue-resident innate lymphoid cells in the lung [PDF]

, 2017

core   +1 more source

Artificial Intelligence (AI)-Powered H&E Whole-Slide Image Analysis of Tertiary Lymphoid Structure (TLS) Independently Predicts Survival in Patients with Non-Small Cell Lung Cancer (NSCLC) Receiving Immunotherapy

ABSTRACT Background Tertiary lymphoid structures (TLSs) within the tumor microenvironment have emerged as potential indicators of treatment response to immune checkpoint inhibitors (ICIs). This study aims to explore the association between artificial intelligence (AI)-powered TLS analysis and treatment ...
Leeseul Kim, Sangwon Shin, Behtash G Nezami, Borislav Alexiev, Soo Ick Cho, Sanghoon Song, Wonkyung Jung, Lee AD Cooper, Donghoon Shin, Junho Song, Taekyu Um, Liam Il-Young Chung, Young Kwang Chae   +12 more
openaire   +1 more source

IMpower110: tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first line atezolizumab ro chemotherapy

Journal for ImmunoTherapy of Cancer, 2023
Srivastava, Minu, Gayevskiy, Velimir, Ma, Vy, Estay, Ivette, de Rodas, Miguel, Rajendram, Barani, Hoang, Tien, Ballinger, Marcus, Amin, Reena, Herbst, Roy, de Marinis, Filippo, Giaccone, Giuseppe, Spigel, David, Schalper, Kurt, Koeppen, Hartmut, Shames, David, Johnston, Robert, Giltnane, Jennifer, Nabet, Barzin   +18 more
openaire   +1 more source

FOXP3⁺ Cells in Tertiary Lymphoid Structures Have Adverse Impact on Overall Survival in Patients with Gastric Cancer. [PDF]

Med Sci (Basel)
Paparella Karaman A, Ivanović T, Mustapić K, Vukojević K, Minarik L, Glavina Durdov M, Đolonga P.   +6 more
europepmc   +1 more source