Results 91 to 100 of about 4,240 (183)

Past failures and new horizons: the nuances of tertiary lymphoid structures in high-grade serous ovarian cancer may contribute to immunotherapy effectiveness

Journal for ImmunoTherapy of Cancer
Tertiary lymphoid structures (TLS) are ectopic lymphoid aggregates that allow for optimal B-T cell crosstalk in solid tumors. Further, TLS are found in many solid tumors and are associated with improved patient survival and superior immunotherapeutic ...
Tullia C Bruno, Ian MacFawn, Lan Coffman, Rufiaat Rashid   +3 more
doaj   +1 more source

Tertiary lymphoid structures in gastrointestinal cancer: orchestrating tumour microenvironmental immune subcycles to elegantly amplify the cancer immunity cycle

Annals of Medicine
Introduction Gastrointestinal (GI) cancers remain a major global health burden, with high incidence and mortality despite advances in multimodal therapies.
Haobo Yin, Yuxi Qiao, Xiaoyan Li, Jingdong Zhang, Qian Dong   +4 more
doaj   +1 more source

Analyses of germinal center B cells and tertiary lymphoid structures (TLS) in mouse and human HNSCC

Laryngo-Rhino-Otologie, 2019
M Sonntag, C Brunner, TK Hoffmann
openaire   +1 more source

606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy

Regular and Young Investigator Award Abstracts, 2023
Robert Johnston, Hartmut Koeppen, Roy S Herbst, Kurt Schalper, Filippo De Marinis, Giuseppe Giaccone, Jacek Jassem, Marcus Ballinger, Barani Kumar Rajendran, David R Spigel, Miguel López de Rodas, Minu K Srivastava, Jennifer M Giltnane, Barzin Y Nabet, David S Shames, Velimir Gayevskiy, Vy Ma, Ivette Estay, Tien Hoang, Reena Amin   +19 more
openaire   +2 more sources

Identification of a tertiary lymphoid structure (TLS)-related signature for ovarian cancer prognosis suggests a potential role of STAT5A in TLS maturation

Genes & Diseases
Jiani Yang, Yue Zhang, Shanshan Cheng, Yanna Xu, Meixuan Wu, Sijia Gu, Mingjun Ma, Yaqian Zhao, Chao Wang, Yu Wang   +9 more
openaire   +3 more sources

Predicting survival in oral squamous cell carcinoma via integrated analysis of tumor budding and tertiary lymphoid structures. [PDF]

Front Oncol
Xiang Z, Huang Y, Yun B, Li D, Liu F, Liu J, Xie N, Zhuang Z, Hou J, Wang C.   +9 more
europepmc   +1 more source

Germinal Center-Like Tertiary Lymphoid Structures Mark Immune Responsiveness and Enable Checkpoint Immunotherapy in Bladder Cancer. [PDF]

Oncol Res
Yin Z, Zhen X, Li H, Duan H, Hu X, Yu T, Shi Q, Liu Z, Li Y, Zhang P, Dai P, Zhao M, Wang Z, Li C, Wang D, Tong Z.   +15 more
europepmc   +1 more source

Comparative Analysis of Pathology Foundation Models for Automated Detection of Tertiary Lymphoid Structures in Hematoxylin-and-Eosin-Stained Digital Pathology Images. [PDF]

Comput Struct Biotechnol J
Guan M, Sun Y, Belete M, Muthuswamy A, Farma M, Kaufmann J, Lechpammer M, Sridhar S, Higgs BW, Si H.   +9 more
europepmc   +1 more source

The biological characteristics of tertiary lymphoid structures in head and neck cancer. [PDF]

Front Immunol
Bai S, Wei Y, Liu F, Sun H, Zeng X, Zhang P.   +5 more
europepmc   +1 more source

Research progress of tertiary lymphoid structure in hepatocellular carcinoma: from prognostic biomarkers to new strategies for immunotherapy. [PDF]

Front Immunol
Yuan S, Luo X, Li S, Cao L, Chen X, Wang L, Liu Y, Li Z, Wu T, Fang H, Tong M.   +10 more
europepmc   +1 more source