Results 91 to 100 of about 4,769 (183)

Tertiary lymphoid structures associated with improved survival and enhanced antitumor immunity in acral melanoma

npj Precision Oncology
Understanding the impact of tertiary lymphoid structures (TLSs) on acral melanoma (AM) and the tumor microenvironment (TME) is critical. We analyzed TLS features in primary AM lesions from 46 patients and identified intratumoral TLSs (intra-TLSs) in 25 ...
Xinyu Su, Donglin Kang, Jiayu Wang, Lin Li, Rong Huang, Zhengyun Zou   +5 more
doaj   +1 more source

Past failures and new horizons: the nuances of tertiary lymphoid structures in high-grade serous ovarian cancer may contribute to immunotherapy effectiveness

Journal for ImmunoTherapy of Cancer
Tertiary lymphoid structures (TLS) are ectopic lymphoid aggregates that allow for optimal B-T cell crosstalk in solid tumors. Further, TLS are found in many solid tumors and are associated with improved patient survival and superior immunotherapeutic ...
Tullia C Bruno, Ian MacFawn, Lan Coffman, Rufiaat Rashid   +3 more
doaj   +1 more source

Tertiary lymphoid structures in colorectal cancer

Annals of Medicine
Background Tertiary lymphoid structures (TLS) are ectopic clusters of immune cells found in non-lymphoid tissues, particularly within the tumor microenvironment (TME).
Jianyu Lv, Xiuyu Zhang, Mi Zhou, Junbin Yan, Guanqun Chao, Shuo Zhang   +5 more
doaj   +1 more source

Analyses of germinal center B cells and tertiary lymphoid structures (TLS) in mouse and human HNSCC

Laryngo-Rhino-Otologie, 2019
M Sonntag, C Brunner, TK Hoffmann
openaire   +1 more source

606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy

Regular and Young Investigator Award Abstracts, 2023
Robert Johnston, Hartmut Koeppen, Roy S Herbst, Kurt Schalper, Filippo De Marinis, Giuseppe Giaccone, Jacek Jassem, Marcus Ballinger, Barani Kumar Rajendran, David R Spigel, Miguel López de Rodas, Minu K Srivastava, Jennifer M Giltnane, Barzin Y Nabet, David S Shames, Velimir Gayevskiy, Vy Ma, Ivette Estay, Tien Hoang, Reena Amin   +19 more
openaire   +2 more sources

Identification of a tertiary lymphoid structure (TLS)-related signature for ovarian cancer prognosis suggests a potential role of STAT5A in TLS maturation

Genes & Diseases
Jiani Yang, Yue Zhang, Shanshan Cheng, Yanna Xu, Meixuan Wu, Sijia Gu, Mingjun Ma, Yaqian Zhao, Chao Wang, Yu Wang   +9 more
openaire   +3 more sources

Histological grading of tertiary lymphoid structures correlates with renal impairment and adverse outcomes in ANCA-associated glomerulonephritis. [PDF]

Front Immunol
Wang Y, Huang K, Fang J, Chen C, Zheng Z, Tao X, Wan J, Chen H, Ma H, Xu Y.   +9 more
europepmc   +1 more source

Non-immune regulation of tertiary lymphoid structures in cancer. [PDF]

Front Immunol
Challen OK, Fitzsimons E, Anderson WW, Liao D, Wu W, Souza VGP, Bénard KH, Naso JR, Martin SD, Lam WL, Enfield KSS.   +10 more
europepmc   +1 more source

IMpower110: tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first line atezolizumab ro chemotherapy

Journal for ImmunoTherapy of Cancer, 2023
Srivastava, Minu, Gayevskiy, Velimir, Ma, Vy, Estay, Ivette, de Rodas, Miguel, Rajendram, Barani, Hoang, Tien, Ballinger, Marcus, Amin, Reena, Herbst, Roy, de Marinis, Filippo, Giaccone, Giuseppe, Spigel, David, Schalper, Kurt, Koeppen, Hartmut, Shames, David, Johnston, Robert, Giltnane, Jennifer, Nabet, Barzin   +18 more
openaire   +1 more source

Editorial: Advancements in tertiary lymphoid structures: insights for cancer treatment. [PDF]

Front Immunol
Xu J, Di X, Liang X.
europepmc   +1 more source