Results 41 to 50 of about 224,987 (336)

Changes in Bone Metabolism and Structure in Primary Hyperparathyroidism

open access: yesActa Medica Bulgarica, 2020
Parathyroid hormone (PTH) is a key regulator of bone turnover. Depending on the duration of action, the hormone causes catabolic and anabolic effects by binding with specific receptors (PTHR1) in the bone.
Yankova I., Shinkov A., Kovatcheva R.
doaj   +1 more source

Features of peripheral blood Treg and Th17 subsets during physiological pregnancy [PDF]

open access: yesExploration of Immunology
Aim: Regulatory T (Treg) cells and interleukin-17-producing T helper (Th17) cells play a critical role in successful pregnancy. Treg and Th17 cells differentiate predominantly in the thymus.
Olga Gorbunova   +3 more
doaj   +1 more source

Yin and yang of interleukin-17 in host immunity to infection [version 1; referees: 2 approved] [PDF]

open access: yes, 2017
The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play important protective roles in host immune response to a variety of infections such as bacterial, fungal, parasitic, and viral.
Das, Shibali, Khader, Shabaana
core   +3 more sources

Erythropoietin inhibits SGK1-dependent Th17 cell induction and Th17 cell–dependent kidney disease [PDF]

open access: yesJCI Insight, 2019
IL-17-producing CD4+ cells (TH17) are pathogenically linked to autoimmunity including to autoimmune kidney disease. Erythropoietin's (EPO) newly recognized immunoregulatory functions and its predominant intra-renal source suggested that EPO physiologically regulates TH17 differentiation, thereby serving as a barrier to the development of autoimmune ...
Chiara Donadei   +13 more
openaire   +4 more sources

How to treat a patient with psoriatic arthritis and chronic lymphocytic leukemia? [PDF]

open access: yesExploration of Musculoskeletal Diseases
A 76-year-old male patient who has been suffering from psoriatic arthritis (PsA) for 15 years was diagnosed with chronic lymphocytic leukemia (CLL) 18 months ago.
Jürgen Braun   +2 more
doaj   +1 more source

Tertiary lymphoid organs in central nervous system autoimmunity [PDF]

open access: yes, 2016
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
core   +1 more source

Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells [PDF]

open access: yes, 2017
Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA.
Aya Castañeda, Maria del Rosario   +6 more
core   +1 more source

Expression of the RUNX family in skin lesions from patients with psoriasis vulgaris

open access: yesPifu-xingbing zhenliaoxue zazhi, 2022
Objective To explore the expression and distribution of runt-related transcription factor (RUNX) family in lesions of psoriasis vulgaris (PV), and analyze the correlation between its levels and markers of proliferation, apoptosis and immunity.
Dan HONG   +4 more
doaj   +1 more source

The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]

open access: yes, 2008
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J.   +7 more
core   +1 more source

Les cellules Th17 [PDF]

open access: yesmédecine/sciences, 2008
After more than 20 years of hegemony, the Th1-Th2 paradigm was recently shaken by the discovery of a novel population of CD4 effector T cells, the Th17 cells. Th17 effector cells produce IL-17 and IL-22 and thus have pro-inflammatory properties notably favoring neutrophils recruitment and thus control of extracellular bacteria mainly at the epithelium ...
Stéphane Leung-Theung-Long   +1 more
openaire   +1 more source

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