Changes in Bone Metabolism and Structure in Primary Hyperparathyroidism
Acta Medica Bulgarica, 2020 Parathyroid hormone (PTH) is a key regulator of bone turnover. Depending on the duration of action, the hormone causes catabolic and anabolic effects by binding with specific receptors (PTHR1) in the bone.
Yankova I., Shinkov A., Kovatcheva R.
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Features of peripheral blood Treg and Th17 subsets during physiological pregnancy [PDF]
Exploration of ImmunologyAim: Regulatory T (Treg) cells and interleukin-17-producing T helper (Th17) cells play a critical role in successful pregnancy. Treg and Th17 cells differentiate predominantly in the thymus.
Olga Gorbunova +3 more
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Yin and yang of interleukin-17 in host immunity to infection [version 1; referees: 2 approved] [PDF]
, 2017 The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play important protective roles in host immune response to a variety of infections such as bacterial, fungal, parasitic, and viral.
Das, Shibali, Khader, Shabaana
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Erythropoietin inhibits SGK1-dependent Th17 cell induction and Th17 cell–dependent kidney disease [PDF]
JCI Insight, 2019 IL-17-producing CD4+ cells (TH17) are pathogenically linked to autoimmunity including to autoimmune kidney disease. Erythropoietin's (EPO) newly recognized immunoregulatory functions and its predominant intra-renal source suggested that EPO physiologically regulates TH17 differentiation, thereby serving as a barrier to the development of autoimmune ...
Chiara Donadei +13 more
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How to treat a patient with psoriatic arthritis and chronic lymphocytic leukemia? [PDF]
Exploration of Musculoskeletal DiseasesA 76-year-old male patient who has been suffering from psoriatic arthritis (PsA) for 15 years was diagnosed with chronic lymphocytic leukemia (CLL) 18 months ago.
Jürgen Braun +2 more
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Tertiary lymphoid organs in central nervous system autoimmunity [PDF]
, 2016 Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
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Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing γδT Cells [PDF]
, 2017 Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA.
Aya Castañeda, Maria del Rosario +6 more
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Expression of the RUNX family in skin lesions from patients with psoriasis vulgaris
Pifu-xingbing zhenliaoxue zazhi, 2022 Objective To explore the expression and distribution of runt-related transcription factor (RUNX) family in lesions of psoriasis vulgaris (PV), and analyze the correlation between its levels and markers of proliferation, apoptosis and immunity.
Dan HONG +4 more
doaj +1 more source
The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]
, 2008 Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J. +7 more
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médecine/sciences, 2008 After more than 20 years of hegemony, the Th1-Th2 paradigm was recently shaken by the discovery of a novel population of CD4 effector T cells, the Th17 cells. Th17 effector cells produce IL-17 and IL-22 and thus have pro-inflammatory properties notably favoring neutrophils recruitment and thus control of extracellular bacteria mainly at the epithelium ...
Stéphane Leung-Theung-Long +1 more
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