Results 21 to 30 of about 24,728 (306)
Polycyclic Aromatic Compounds, 2021 A new series of 4-aryl-2-(naphthalen-1-yl)thiazole (7a-b), 4-aryl/pyridyl-2-(2-substituted quinolin-4-yl)thiazole (13a-o) and 4-(pyridin-4-yl)-2-(quinolin-4-yl)thiazole (15) have been synthesized. The newly synthesized compounds were evaluated for anticancer activity against breast cell lines MDA-MB-231 and MCF-7.
Pravin C. Mhaske +5 more
openaire +2 more sources
Thiazole-Bearing 4-Thiazolidinones as New Anticonvulsant Agents
Scientia Pharmaceutica, 2020 Here, we describe the synthesis and anticonvulsant activity of thiazole-bearing hybrids based on 2-imino-4-thiazolidinone and 2,4-dioxothiazolidine-5-carboxylic acid cores.
Mariia Mishchenko +3 more
doaj +1 more source
Microwave-assisted generation and reactivity of aza- and diazafulvenium methides: heterocycles via pericyclic reactions [PDF]
, 2008 Azafulvenium methides and diazafulvenium methides have been generated under microwave irradiation from 2,2-dioxo-1H,3H-pyrrolo[1,2-c]thiazoles and 2,2-dioxo-1H,3H-pyrazolo[1,5-c]thiazoles, respectively.
Melo, Teresa M. V. D. Pinho e +1 more
core +1 more source
Methyl 2-amino-5-isopropyl-1,3-thiazole-4-carboxylate [PDF]
, 2004 The title compound, C8H12N2O2S, forms a supramolecular network based on N-HN hydrogen-bonded centrosymmetric dimers that are linked in turn by N-HO ...
Kennedy, Alan R. +3 more
core +1 more source
Thiazole formation through a modified Gewald reaction
Beilstein Journal of Organic Chemistry, 2015 The synthesis of thiazoles and thiophenes starting from nitriles, via a modified Gewald reaction has been studied for a number of different substrates. 1,4-Dithiane-2,5-diol was used as the aldehyde precursor to give either 2-substituted thiazoles or 2 ...
Carl J. Mallia +3 more
doaj +1 more source
Synthesis of various fused pyrimidine rings with their pharmacological and antimicrobial evaluation [PDF]
Journal of the Serbian Chemical Society, 2014 Various fused pyrimidine such as furo[2,3-d]pyrimidine, triazolo[1,5-a]pyrimidine, tetrazolo[1,5-a]pyrimidine were synthesized from the reactions of thioxopyrimidine-6(1H)-ones with ethyl chloroacetate (under different reaction conditions ...
Mounir Salem A. +2 more
doaj +1 more source
The Synthesis of Novel 2-Hetarylthiazoles via the Stille Reaction
Журнал органічної та фармацевтичної хімії, 2023 A preparative approach to the synthesis of 2-hetaryl thiazoles has been developed via the interaction of halothiazoles with stannanes according to the Stille reaction. The most effective catalysts and reaction conditions have been found.
Dmytro O. Tarasenko +1 more
doaj +1 more source
Synthesis and Biological Evaluation of Bisthiazoles and Polythiazoles
Molecules, 2018 Small heterocyclic compounds containing nitrogen and sulfur atoms, such as thiazole derivatives, represent a significant class of organic azoles that exhibit promising bioactivities and have a great potential in medicinal and agricultural fields.
Mohammed A. Al-Omair +2 more
doaj +1 more source
Pyridin-2-ylthiazolothiazoles – Synthesis and photophysical properties
Results in Chemistry, 2021 Thiazolo[5,4-d]thiazoles are valuable materials for a range of technical and biological applications. They are used as chemosensors, electroluminescent materials, organic light-emitting diodes (OLEDs), in solar cells, in live-cell imaging, etc., and for ...
Ana F.R. Cerqueira +3 more
doaj
Thiazoles in Peptides and Peptidomimetics [PDF]
, 2015 The natural occurrence of the thiazole ring in chemistry and biology has inspired its widespread use in synthetic peptidomimetics as structural templates, biological probes, and pharmaceuticals. Thiazole can be viewed as a dehydrated cyclized derivative of cysteine, incorporated into peptide sequences through chemical synthesis or ribosomal ...
Mak, Jeffrey Y. W. +2 more
openaire +3 more sources