Results 21 to 30 of about 196,709 (295)
Progress in Biophysics and Molecular Biology, 2003 A fundamental function of epithelia and endothelia is to separate different compartments within the organism and to regulate the exchange of substances between them. The tight junction (TJ) constitutes the barrier both to the passage of ions and molecules through the paracellular pathway and to the movement of proteins and lipids between the apical and
L, González-Mariscal +3 more
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BMC Cell Biology, 2009 Background Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge.
Balda Maria S +3 more
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Tight Junctions of the Neurovascular Unit
Frontiers in Molecular Neuroscience, 2021 The homeostatic balance of the brain and retina is maintained by the presence of the blood-brain and inner blood-retinal barrier (BBB/iBRB, respectively) which are highly specialized barriers.
Natalie Hudson, Matthew Campbell
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Viruses, 2015 Tight junctions (TJs) are highly specialized membrane domains involved in many important cellular processes such as the regulation of the passage of ions and macromolecules across the paracellular space and the establishment of cell polarity in ...
Jesús M. Torres-Flores, Carlos F. Arias
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Effects of acute and chronic disease on cell junctions in mouse liver
EXCLI Journal : Experimental and Clinical Sciences, 2023 Cell junctions, including anchoring, occluding and communicating junctions, play an indispensable role in tissue architecture and homeostasis. Consequently, malfunctioning of cell junctions is linked with a wide range of disorders, including in liver ...
Raf Van Campenhout +2 more
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Developmental expression of claudins in the mammary gland [PDF]
, 2017 Claudins are a large family of membrane proteins whose classic function is to regulate the permeability of tight junctions in epithelia. They are tetraspanins, with four alpha-helices crossing the membrane, two extracellular loops, a short cytoplasmic N ...
Baumgartner, Heidi K. +8 more
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VE-cadherin and claudin-5: it takes two to tango [PDF]
, 2008 Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively.
A Taddei +17 more
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Cells, 2022 Formation and maintenance of tissue barriers require the coordination of cell mechanics and cell–cell junction assembly. Here, we combined methods to modulate ECM stiffness and to measure mechanical forces on adhesion complexes to investigate how tight ...
Alexis J. Haas +8 more
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 Aim. Comparative study of tight junctions and ultrastructure alterations of enterocytes of mucous membranes of jejunum of rats under the effect of lipopolysaccharides and cholera toxin. Materials and methods.
O. N. Vishnevskaya +4 more
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Cells, 2021 Dysfunction of the endothelial barrier plays a central role in the pathogenesis of both acute and chronic inflammatory processes such as sepsis or atherosclerosis.
Daniel Maucher +2 more
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