Results 31 to 40 of about 196,709 (295)

Disruption of Claudin-Made Tight Junction Barriers by Clostridium perfringens Enterotoxin: Insights from Structural Biology

open access: yesCells, 2022
Claudins are a family of integral membrane proteins that enable epithelial cell/cell interactions by localizing to and driving the formation of tight junctions.
Chinemerem P. Ogbu   +2 more
doaj   +1 more source

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis [PDF]

open access: yes, 2017
Background: Dysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied.
Alessandro, Riccardo   +13 more
core   +2 more sources

Structural dynamics of tight junctions modulate the properties of the epithelial barrier.

open access: yesPLoS ONE, 2019
Tight junctions are dynamic structures that are crucial in establishing the diffusion and electrical barrier of epithelial monolayers. Dysfunctions in the tight junctions can impede this barrier function and lead to many pathological conditions ...
Aapo Tervonen   +3 more
doaj   +1 more source

Listeria monocytogenes invades the epithelial junctions at sites of cell extrusion. [PDF]

open access: yesPLoS Pathogens, 2006
Listeria monocytogenes causes invasive disease by crossing the intestinal epithelial barrier. This process depends on the interaction between the bacterial surface protein Internalin A and the host protein E-cadherin, located below the epithelial tight ...
Mickey Pentecost   +3 more
doaj   +2 more sources

ZOning out Tight Junctions [PDF]

open access: yesCell, 2006
The tight junction is an intricate seal between adjoining epithelial cells that also separates the apical and basolateral membranes within these cells. A paper in this issue of Cell by Umeda et al. (2006) demonstrates that loss of the ZO scaffolding proteins prevents the formation of tight junctions but surprisingly does not perturb apico-basal ...
Shin, K, Margolis, B
openaire   +3 more sources

The ACE2 Receptor for Coronavirus Entry Is Localized at Apical Cell—Cell Junctions of Epithelial Cells

open access: yesCells, 2022
Transmembrane proteins of adherens and tight junctions are known targets for viruses and bacterial toxins. The coronavirus receptor ACE2 has been localized at the apical surface of epithelial cells, but it is not clear whether ACE2 is localized at apical
Florian Rouaud   +2 more
doaj   +1 more source

Tight junction proteins.

open access: yesBiochimica et biophysica acta, 1998
A fundamental function of epithelia and endothelia is to separate different compartments within the organism and to regulate the exchange of substances between them. The tight junction (TJ) constitutes the barrier both to the passage of ions and molecules through the paracellular pathway and to the movement of proteins and lipids between the apical and
CITI, SANDRA, CORDENONSI, MICHELANGELO
openaire   +3 more sources

Interplay between tight junctions & adherens junctions [PDF]

open access: yesExperimental Cell Research, 2017
Cell-cell adhesions are critical for the development and maintenance of tissues. Present at sites of cell-cell contact are the adherens junctions and tight junctions. The adherens junctions mediate cell-cell adhesion via the actions of nectins and cadherins.
Hannah K, Campbell   +2 more
openaire   +2 more sources

Chitosan encapsulation modulates the effect of capsaicin on the tight junctions of MDCK cells [PDF]

open access: yes, 2015
Capsaicin has known pharmacological effects including the ability to reversibly open cellular tight junctions, among others. The aim of this study was to develop a strategy to enhance the paracellular transport of a substance with low permeability (FITC ...
A- Choi   +42 more
core   +1 more source

Cell–Cell Interaction Proteins (Gap Junctions, Tight Junctions, and Desmosomes) and Water Transporter Aquaporin 4 in Meningothelial Cells of the Human Optic Nerve

open access: yesFrontiers in Neurology, 2017
PurposeMeningothelial cells (MECs) play a central role in the maintenance of cerebrospinal fluid (CSF) homeostasis and in physiological and pathophysiological processes within the subarachnoid space (SAS) linking them to optic nerve (ON) pathologies ...
Thi Ngoc Co Zeleny   +8 more
doaj   +1 more source

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