Results 91 to 100 of about 12,406 (222)

The Mechanism of Gut Microbiota in Breast Cancer Based on the Bulk Transcriptome, Mendelian Randomization Analysis and Single Cell RNA Sequencing

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
This multi‐omics study defines the gut microbiota‐driven MCM6/NR3C1 axis as a key driver of breast cancer, providing robust biomarkers for early diagnosis and actionable therapeutic targets. ABSTRACT Breast cancer (BC) is the leading cause of cancer death in women.
Tianyu Luo, Mengyao Xue, Yi Du, Huiying Chen, Ying Sun, Haidong Sun   +5 more
wiley   +1 more source

Influence of major structural features of tocopherols and tocotrienols on their ω-oxidation by tocopherol-ω-hydroxylase

Journal of Lipid Research, 2007
Human cytochrome P450 4F2 (CYP4F2) catalyzes the initial ω-hydroxylation reaction in the metabolism of tocopherols and tocotrienols to carboxychromanols and is, to date, the only enzyme shown to metabolize vitamin E.
Timothy J. Sontag, Robert S. Parker
doaj   +1 more source

Metabolic and Redox‐Related Effects of Mauritia flexuosa (Buriti) Oil Supplementation in Wistar Rats

Journal of Food Science, Volume 91, Issue 4, April 2026.
ABSTRACT Mauritia flexuosa (buriti) oil is rich in oleic and palmitic fatty acids, bioactive compounds associated with inflammation regulation, redox balance, and metabolism. This study evaluated the effects of buriti oil supplementation on body and bone composition, biochemical parameters, and redox balance in male Wistar rats.
Letícia de Almeida Sant’ Anna Trindade, Beatriz Alem Nascimento de Araújo, Gabriel de Alcantara Noblat, Karen Pereira Coutinho, Karla de Araújo Coutinho, Renata Nascimento Matoso Souto, Anderson Junger Teodoro, Aline D'Avila Pereira, Mariana Sarto Figueiredo   +8 more
wiley   +1 more source

Membrane composition and dynamics: A target of bioactive virgin olive oil constituents [PDF]

, 2015
The endogenous synthesis of lipids, which requires suitable dietary raw materials, is critical for the formation of membrane bilayers. In eukaryotic cells, phospholipids are the predominant membrane lipids and consist of hydrophobic acyl chains attached ...
Abia, Rocío, Bermúdez, Beatriz, Jaramillo Carmona, Sara M., López, Sergio, Montserrat-de la Paz, Sergio, Muriana, Francisco J. G., Ortega, Almudena, Varela, Lourdes   +7 more
core   +2 more sources

When Pathways Converge: Iron, Lipid Peroxidation, and α‐Synuclein in Ferroptosis‐Driven Dopaminergic Neurodegeneration

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich, Brent R. Stockwell, Marcelo Farina   +2 more
wiley   +1 more source

Preparation and Characterizationof Palm-Based Functional Lipid Nanodispersions [PDF]

, 2008
Poor solubility of functional lipids has made their use problematic in food industry especially in food formulations. The difficulties to find a suitable formulation or solution are even greater especially when the functional lipids are poorly soluble ...
Cheong, Jean Ne
core  

Delta- and gamma-tocotrienol isomers are potent in inhibiting inflammation and endothelial activation in stimulated human endothelial cells

Food & Nutrition Research, 2016
Background: Tocotrienols (TCTs) are more potent antioxidants than α-tocopherol (TOC). However, the effectiveness and mechanism of the action of TCT isomers as anti-atherosclerotic agents in stimulated human endothelial cells under inflammatory conditions
Suhaila Muid, Gabriele R. Anisah Froemming, Thuhairah Rahman, A. Manaf Ali, Hapizah M. Nawawi   +4 more
doaj   +1 more source

Comparison of geranylgeranyl and phytyl substituted methylquinols in the tocopherol synthesis of spinach chloroplasts [PDF]

, 1979
Geranylgeranyl substituted methylquinols are shown to be precursors of tocopherol biosynthesis in spinach chloroplasts as well as phytyl substituted ones.
Chow, Gernot Schultz, Janiszowska, Jensen, Jürgen Soll, Mayer, Soll, Wellburn, Whistance   +8 more
core   +1 more source

L'évolution récente de l'huile de palme [PDF]

, 1990
Plusieurs thèmes d'intérêt pratique ont été choisis · 1 -A l'occasion d'une étude approfondie aux Pays-Bas sur la nutrition humaine, de nombreux produits alimentaires de consommation courante ont été reformulés de façon à contenir un maximum d'huile de ...
Berger, K.G.
core  

Antioxidative Activity of Tocotrienols

Journal of Japan Oil Chemists' Society, 1985
The antioxidative activity of α-and γ-tocotrienols in methyl linoleate was tested by weighing method at 60°C and was compared with that of α- and γ-tocopherols. Tocotrienols showed slightly superior or equal antioxidative activity to the corresponding tocopherols.
Masakazu YAMAOKA, Akio TANAKA, Akio KATO
openaire   +2 more sources