Results 71 to 80 of about 4,753 (175)

Natural Product‐Derived Vesicles in Nanotherapeutics

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

Influence of major structural features of tocopherols and tocotrienols on their ω-oxidation by tocopherol-ω-hydroxylase

Journal of Lipid Research, 2007
Human cytochrome P450 4F2 (CYP4F2) catalyzes the initial ω-hydroxylation reaction in the metabolism of tocopherols and tocotrienols to carboxychromanols and is, to date, the only enzyme shown to metabolize vitamin E.
Timothy J. Sontag, Robert S. Parker
doaj   +1 more source

Genetic dissection of southern corn leaf blight resistance in sweet corn through genome‐wide association studies and genomic selection

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Southern corn leaf blight (SCLB) is caused by the fungal pathogen Bipolaris maydis (syn. Cochliobolus heterostrophus Drechsler) and is a common disease of fall crops of sweet corn. Phenotyping for SCLB resistance is performed through visual scoring, which is subjective and may limit genetic gain for this quantitative trait.
Darlon V. Lantican, Juan M. Gonzalez, Marco Antonio Peixoto, Kristen A. Leach, Larissa Carvalho Ferreira, Vitor A. Silva de Moura, Katia V. Xavier, Peter Balint‐Kurti, William Tracy, Marcio F. R. Resende Jr.   +9 more
wiley   +1 more source

Anti-angiogenic Activity of Tocotrienol

Bioscience, Biotechnology, and Biochemistry, 2003
The anti-angiogenic property of vitamin E compounds, with particular emphasis on tocotrienol, has been investigated in vitro. Tocotrienol, but not tocopherol, inhibited both the proliferation and tube formation of bovine aortic endothelial cells, with delta-tocotrienol appearing the highest activity.
INOKUCHI, Hitoshi, HIROKANE, Hisako, TSUZUKI, Tsuyoshi, NAKAGAWA, Kiyotaka, IGARASHI, Miki, MIYAZAWA, Teruo   +5 more
openaire   +2 more sources

Delta- and gamma-tocotrienol isomers are potent in inhibiting inflammation and endothelial activation in stimulated human endothelial cells

Food & Nutrition Research, 2016
Background: Tocotrienols (TCTs) are more potent antioxidants than α-tocopherol (TOC). However, the effectiveness and mechanism of the action of TCT isomers as anti-atherosclerotic agents in stimulated human endothelial cells under inflammatory conditions
Suhaila Muid, Gabriele R. Anisah Froemming, Thuhairah Rahman, A. Manaf Ali, Hapizah M. Nawawi   +4 more
doaj   +1 more source

Effect of Tocotrienols on Lipid Profile in Rabbits

Journal of Rawalpindi Medical College, 2012
Background: To evaluate the effect of tocotrienols on serum lipids in cholesterol-fed rabbits. Methods: In this experimental study, thirty six, male New Zealand white rabbits were randomly allocated to three equal groups.
Uzma Shahid
doaj  

Triacylglycerol Composition of Seed Oil from Corema album Berries

Molecules
The seeds of Corema album are considered a by-product in fruit processing. This study aimed to determine the oil contents in seeds and characterize their triacylglycerol contents through a comparative analysis using three extraction solvent systems ...
Carmen Martín-Cordero, Enrique Martinez-Force, Nuria Acero de Mesa, Dolores Muñoz-Mingarro, Antonio J. León-González   +4 more
doaj   +1 more source

β-Tocotrienol Decreases PDGF-BB-Induced Proliferation and Migration of Human Airway Smooth Muscle Cells by Inhibiting RhoA and Reducing ROS Production

Pharmaceuticals
Background: Tocotrienols exhibit antioxidant and anti-inflammatory activities. RhoA, a small GTPase protein, plays a crucial role in regulating contractility in airway smooth muscle (ASM). Previous studies have demonstrated that γ-tocotrienols reduce ASM
Aditya Sri Listyoko, Ryota Okazaki, Tomoya Harada, Miki Takata, Masato Morita, Hiroki Ishikawa, Yoshihiro Funaki, Akira Yamasaki   +7 more
doaj   +1 more source

Molecular Insights in the Anticancer Activity of Natural Tocotrienols: Targeting Mitochondrial Metabolism and Cellular Redox Homeostasis

Antioxidants
The role of mitochondria as the electric engine of cells is well established. Over the past two decades, accumulating evidence has pointed out that, despite the presence of a highly active glycolytic pathway (Warburg effect), a functional and even ...
Raffaella Chiaramonte, Giulia Sauro, Domenica Giannandrea, Patrizia Limonta, Lavinia Casati   +4 more
doaj   +1 more source

Single-centre, randomised clinical trial of the immunomodulatory mechanisms of daily supplementation of palm tocotrienol-rich fraction in healthy human volunteers following influenza vaccination [version 1; peer review: 1 approved, 2 approved with reservations]

F1000Research
Background Vitamin E from palm oil, known as the tocotrienol-rich fraction (TRF), has been shown to have immune-enhancing activity. To date, only one dose of TRF (400 mg daily) has been tested in a clinical trial.
Cheng Zsien Zhin, Sitti Rahma Abdul Hafid, Uma Devi Palanisamy, Badariah Ahmad, Kanga Rani Selvaduray, Ammu Kutty Radhakrishnan   +5 more
doaj   +1 more source