Results 21 to 30 of about 2,567 (176)

Roles of protein–protein interactions and monolayer mechanics in tricellulin localization to tricellular tight junctions [PDF]

open access: yesBiology Open
Toiba Mushtaq   +7 more
doaj   +2 more sources

The Predictive Value of Serum DAO, HDC, and MMP8 for the Gastrointestinal Injury in the Early Stage of Acute Pancreatitis in an Animal Model and a Clinical Study [PDF]

open access: yesInternational Journal of General Medicine
Ruoxi Cheng,1,* Jie Wang,1,* Qing Wu,1 Peng Peng,1 Guolin Liao,1 Xiuping Luo,1 Zhihai Liang,2 Jiean Huang,1,* Mengbin Qin1,* 1Department of Gastroenterology, the Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007 ...
Cheng R   +8 more
doaj   +2 more sources

Identification of amino acids essential for angulin-1/3 binding of the tricellular tight junction binder, angubindin-1. [PDF]

open access: yesFEBS Open Bio
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Kuzu T   +8 more
europepmc   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases. [PDF]

open access: yesFEBS Lett
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Zeyneloglu C   +17 more
europepmc   +2 more sources

Loss of Occludin Affects Tricellular Localization of Tricellulin [PDF]

open access: yesMolecular Biology of the Cell, 2008
The tricellular tight junction (tTJ) forms at the convergence of bicellular tight junctions (bTJs) where three epithelial cells meet in polarized epithelia, and it is required for the maintenance of the transepithelial barrier. Tricellulin is a four transmembrane domain protein recently identified as the first marker of tTJ, but little is known about ...
Junichi, Ikenouchi   +4 more
  +9 more sources

Expression and clinical significance of tricellulin in colorectal cancer and its relationship with angiogenesis

open access: yes结直肠肛门外科, 2022
[Objectives] To investigate the clinical significance of tricellular tight junction protein (tricellulin) in colorectal cancer and its relationship with angiogenesis.
Li Mengshi   +6 more
doaj   +1 more source

Tricellulin Effect on Paracellular Water Transport [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
In epithelia, large amounts of water pass by transcellular and paracellular pathways, driven by the osmotic gradient built up by the movement of solutes. The transcellular pathway has been molecularly characterized by the discovery of aquaporin membrane channels. Unlike this, the existence of a paracellular pathway for water through the tight junctions
Carlos Ayala-Torres   +4 more
openaire   +2 more sources

Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice. [PDF]

open access: yesPLoS ONE, 2015
Tricellular tight junctions seal the extracellular spaces of tricellular contacts, where the vertices of three epithelial cells meet, and are required for the establishment of a strong barrier function of the epithelial cellular sheet.
Tomohito Higashi   +3 more
doaj   +1 more source

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