Results 41 to 50 of about 2,567 (176)
PLoS ONE, 2019 Tight junctions (TJs) are cellular junctions within the mammalian epithelial cell sheet that function as a physical barrier to molecular transport within the intercellular space. Dysregulation of TJs leads to various diseases.
Daiki Nakatsu +3 more
doaj +1 more source
The tight junction protein claudin-1 influences cranial neural crest cell emigration [PDF]
, 2012 The neural crest is a population of migratory cells that follows specific pathways during development, eventually differentiating to form parts of the face, heart, and peripheral nervous system, the latter of which includes contributions from placodal ...
Bronner, Marianne E. +4 more
core +1 more source
Claudin-9 constitutes tight junctions of folliculo-stellate cells in the anterior pituitary gland
Scientific Reports, 2021 The anterior pituitary gland regulates growth, metabolism, and reproduction by secreting hormones. Folliculo-stellate (FS) cells are non-endocrine cells located among hormone-producing cells in the anterior pituitary glands.
Atsuko Y. Higashi +5 more
doaj +1 more source
Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells. [PDF]
PLoS ONE, 2017 Tricellular tight junctions (tTJs) are specialized structures that occur where the corners of three cells meet to seal adjacent intercellular space. The molecular components of tTJs include tricellulin (TRIC) and lipolysis-stimulated lipoprotein receptor
Kenichi Takano +6 more
doaj +1 more source
Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption [PDF]
, 2020 The epithelial sodium channel (ENaC) can increase the colonic absorptive capacity for salt and water. Campylobacter concisus is a common pathogenic epsilonproteobacterium, causing enteritis and diarrhea. It can induce barrier dysfunction in the intestine,
Bereswill, Stefan +15 more
core +2 more sources
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells [PDF]
The Journal of Cell Biology, 2005 For epithelia to function as barriers, the intercellular space must be sealed. Sealing two adjacent cells at bicellular tight junctions (bTJs) is well described with the discovery of the claudins. Yet, there are still barrier weak points at tricellular contacts, where three cells join together. In this study, we identify tricellulin, the first integral
Ikenouchi, Junichi +5 more
openaire +2 more sources
Advanced Science, 2020 Collective cellular behavior in confluent monolayers supports physiological and pathological processes of epithelial development, regeneration, and carcinogenesis. Here, the attainment of a mature and static tissue configuration or the local reactivation
Sophie Lohmann +7 more
doaj +1 more source
Expression of Tight Junction Components in Hepatocyte-Like Cells Differentiated from Human Embryonic Stem Cells [PDF]
, 2015 Human embryonic stem cells can be differentiated in vitro into a wide variety of progeny cells by addition of different morphogens and growth factors. Our aim was to monitor the expression pattern of tight junction (TJ) components and various cellular ...
Apáti, Ágota +6 more
core +1 more source
MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus. [PDF]
, 2016 Ocular morphogenesis requires several signalling pathways controlling the expression of transcription factors and cell-cycle regulators. However, despite a well-known mechanism, the dialogue between those signals and factors remains to be unveiled. Here,
Balda, MS +7 more
core +4 more sources
Cell Communication and Signaling, 2023 Chronic rhinosinusitis (CRS) is a pathological condition characterized by persistent inflammation in the upper respiratory tract and paranasal sinuses.
Zahra Chegini +4 more
doaj +1 more source