Results 51 to 60 of about 2,567 (176)

Human peritoneal tight junction, transporter and channel expression in health and kidney failure, and associated solute transport

Scientific Reports, 2023
Next to the skin, the peritoneum is the largest human organ, essentially involved in abdominal health and disease states, but information on peritoneal paracellular tight junctions and transcellular channels and transporters relative to peritoneal ...
Eszter Levai, Iva Marinovic, Maria Bartosova, Conghui Zhang, Betti Schaefer, Hanna Jenei, Zhiwei Du, Dorota Drozdz, Günter Klaus, Klaus Arbeiter, Philipp Romero, Vedat Schwenger, Constantin Schwab, Attila J. Szabo, Sotirios G. Zarogiannis, Claus Peter Schmitt   +15 more
doaj   +1 more source

Establishment of a novel probe-based RT-qPCR approach for detection and quantification of tight junctions reveals age-related changes in the gut barriers of broiler chickens.

PLoS ONE, 2021
Tight junctions (TJs) play a dominant role in gut barrier formation, therefore, resolving the structures of TJs in any animal species is crucial but of major importance in fast growing broilers. They are regulated in molecular composition, ultrastructure
J Sophia von Buchholz, Ivana Bilic, Jörg R Aschenbach, Michael Hess, Taniya Mitra, Wageha A Awad   +5 more
doaj   +1 more source

Tight junction physiology of pleural mesothelium [PDF]

, 2014
Pleura consists of visceral and parietal cell layers, producing a fluid, which is necessary for lubrication of the pleural space. Function of both mesothelial cell layers is necessary for the regulation of a constant pleural fluid volume and ...
Amasheh, Salah, Markov, Alexander G.
core   +2 more sources

Association of tricellulin expression with poor colorectal cancer prognosis and metastasis

Oncology Reports, 2020
Tricellulin is a tight‑junction transmembrane protein that regulates cell‑cell interactions. Altered tricellulin expression could promote tumor cell invasions and metastasis in human cancers. The present study assessed tricellulin expression in colorectal cancer tissues for any association with clinicopathological features of colorectal cancer patients
Zhang, Jin-Xiu, Qin, Meng-Bin, Ye, Zhe, Peng, Peng, Li, Si-Man, Song, Qian, Lin, Lan, Liu, Shi-Quan, Xie, Li-Hua, Zhu, Ye, Huang, Jie-An   +10 more
openaire   +3 more sources

Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis. [PDF]

, 2018
Patients afflicted with ulcerative colitis (UC) are at increased risk of colorectal cancer. While its causes are not fully understood, UC is associated with defects in colonic epithelial barriers that sustain inflammation of the colon mucosa caused by ...
Alexander, Walker, Dilbarova, Rima, Gilligan, John, Hoxha, Kevther, Kossenkov, Andrew, Mullin, James M., Prendergast, George C., Thomas, Sunil, Whittaker, Kelly   +8 more
core   +2 more sources

Tricellulin regulates junctional tension of epithelial cells at tricellular contacts via Cdc42 [PDF]

Journal of Cell Science, 2014
When the surface view of each epithelial cell is compared with a polygon, its sides correspond to cell–cell junctions, while its vertices correspond to tricellular contacts, whose roles in epithelial cell morphogenesis have not been well studied. Here, we show that tricellulin, which is localized at tricellular contacts, regulates F-actin organization ...
Yukako, Oda, Tetsuhisa, Otani, Junichi, Ikenouchi, Mikio, Furuse   +3 more
openaire   +2 more sources

Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices

Journal of Cell Biology, 2022
Tricellular junctions play a critical role in regulating epithelial barrier function. In this issue, Cho et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202009037) demonstrate a novel interaction between tricellulin and α-catenin, which connects tricellular junctions to the actomyosin cytoskeleton, thus supporting the epithelial barrier at cell ...
Lotte van den Goor, Ann L. Miller
openaire   +2 more sources

Comparison of the performance of raw and Lactobacillus paracasei fermented soybean meal in diets for turbot (Scophthalmus maximus L.): Growth, intestinal morphology, apoptosis, tight junction, and microbiota

Aquaculture Reports, 2022
Fermentation is a promising method to improve the utilization of soybean meal (SM) by fish, and strain is the core of fermentation process. In this study, the effects of Lactobacillus paracasei fermentation on the SM quality were investigated. Also, an 8-
Beili Zhang, Yan Zhang, Meichen Cui, Mengyu Zhang, Jianing Xu, Zhi Zhang, Zhongmin Sui, Lei Wang, Chunyang Zhang, Chaoqun Li, Qinyuan Ma   +10 more
doaj   +1 more source

Ectoplasmic specialization: A friend or a foe of spermatogenesis? [PDF]

, 2007
The ectoplasmic specialization (ES) is a testis-specific, actin-based hybrid anchoring and tight junction. It is confined to the interface between Sertoli cells at the blood-testis barrier, known as the basal ES, as well as between Sertoli cells and ...
Cheng, CY, Lee, WM, Mruk, DD, Yan, HHN
core   +5 more sources

Tricellulin Expression and its Prognostic Significance in Primary Liver Carcinomas

Pathology & Oncology Research, 2014
Numerous data suggest that altered expression of tight junction proteins such as occludin and claudins plays important role in carcinogenesis. However, little is known about tricellulin, a transmembrane tight junction protein concentrated where three epithelial cells meet. We aimed to characterize tricellulin expression in normal and cirrhotic liver in
Somorácz, Áron, Korompay, Anna, Törzsök, Péter, Patonai, Attila, Erdélyi-Belle, Boglárka, Lotz, Gábor, Schaff, Zsuzsa, Kiss, András   +7 more
openaire   +3 more sources