Results 11 to 20 of about 85,493 (199)

Cholinesterases in Tripartite Neuromuscular Synapse [PDF]

Frontiers in Molecular Neuroscience, 2021
The neuromuscular junction (NMJ) is a tripartite synapse in which not only presynaptic and post-synaptic cells participate in synaptic transmission, but also terminal Schwann cells (TSC).
Konstantin A. Petrov, Svetlana E. Proskurina, Eric Krejci   +2 more
doaj   +4 more sources

Beyond NMDA Receptors: Homeostasis at the Glutamate Tripartite Synapse and Its Contributions to Cognitive Dysfunction in Schizophrenia [PDF]

International Journal of Molecular Sciences, 2022
Cognitive deficits are core symptoms of schizophrenia but remain poorly addressed by dopamine-based antipsychotic medications. Glutamate abnormalities are implicated in schizophrenia-related cognitive deficits.
Inna Gaisler-Salomon
exaly   +3 more sources

Sensing and Regulating Synaptic Activity by Astrocytes at Tripartite Synapse [PDF]

Neurochemical Research, 2021
Astrocytes are recognized as more important cells than historically thought in synaptic function through the reciprocal exchange of signaling with the neuronal synaptic elements. The idea that astrocytes are active elements in synaptic physiology is conceptualized in the Tripartite Synapse concept.
José Antonio Noriega Prieto, Alfonso Araque   +1 more
exaly   +4 more sources

Cell adhesion and matricellular support by astrocytes of the tripartite synapse [PDF]

Progress in Neurobiology, 2018
Astrocytes contribute to the formation, function, and plasticity of synapses. Their processes enwrap the neuronal components of the tripartite synapse, and due to this close interaction they are perfectly positioned to modulate neuronal communication ...
Burbach, J. Peter H., J. Peter H. Burbach, Hillen, Anne E J, Hol, Elly M., Elly M. Hol, Hillen, Anne E. J., Anne E.J. Hillen, Burbach, J Peter H, Hol, Elly M   +8 more
core   +4 more sources

A Distinct Perisynaptic Glial Cell Type Forms Tripartite Neuromuscular Synapses in the Drosophila Adult. [PDF]

PLoS ONE, 2015
Previous studies of Drosophila flight muscle neuromuscular synapses have revealed their tripartite architecture and established an attractive experimental model for genetic analysis of glial function in synaptic transmission.
Alexandra L Strauss, Fumiko Kawasaki, Richard W Ordway   +2 more
doaj   +2 more sources

Gliotransmission and the tripartite synapse

, 2012
In the last years, the classical view of glial cells (in particular of astrocytes) as a simple supportive cell for neurons has been replaced by a new vision in which glial cells are active elements of the brain.
Bezzi P, Santello M, Mirko Santello, Paola Bezzi, Calì C, Corrado Calì   +5 more
core   +6 more sources

Structural basis of astrocytic Ca2+ signals at tripartite synapses [PDF]

Nature Communications, 2020
Astrocytic Ca2+ signals can be fast and local, supporting the idea that astrocytes have the ability to regulate single synapses. However, the anatomical basis of such specific signaling remains unclear, owing to difficulties in resolving the spongiform ...
Misa Arizono, V. V. G. Krishna Inavalli, Aude Panatier, Thomas Pfeiffer, Julie Angibaud, Florian Levet, Mirelle J. T. Ter Veer, Jillian Stobart, Luigi Bellocchio, Katsuhiko Mikoshiba, Giovanni Marsicano, Bruno Weber, Stéphane H. R. Oliet, U. Valentin Nägerl   +13 more
doaj   +6 more sources

Synaptic Mitochondrial Oxidative Stress Contributes to Individual Variability in Age-Related Cognitive Inflexibility in Mice. [PDF]

Aging Cell
Aged mice showed substantial individual variability in cognitive inflexibility, associated with greater abundance of synapse‐associated mitochondrial proteins in the medial prefrontal cortex. The mitochondria‐targeted antioxidant MitoQ improved attentional set‐shifting performance and reduced the abundance of synaptosomal mitochondrial proteins ...
Yamada R, Nagai H, Numa C, Zhu Y, Nagai M, Ota K, Kawashima Y, Ohno N, Furuyashiki T.   +8 more
europepmc   +2 more sources

Circadian rhythms of neuronal and astrocytic glutamate transporters in the suprachiasmatic nucleus of mice [PDF]

Frontiers in Cellular Neuroscience
Retinal ganglion cells release glutamate at their synapses, transmitting visual signals via the optic nerve to brain regions involved in vision and light-dependent functions.
Hussein Haidar, Amira A. H. Ali, Amira A. H. Ali, Charlotte von Gall, Federica Tundo-Lavalle   +4 more
doaj   +2 more sources

Dopaminergic Control over the Tripartite Synapse. [PDF]

Neuron, 2020
In this issue of Neuron, Corkrum et al. (2020) demonstrate an unexpected role for dopamine D1 receptors on astrocytes located in the nucleus accumbens, a key structure of the brain's reward system. Activation of these receptors mediates dopamine-evoked depression of excitatory synaptic transmission, which contributes to amphetamine's psychomotor ...
Verharen JPH, de Jong JW, Lammel S.
europepmc   +6 more sources