Results 31 to 40 of about 85,493 (199)
Dissecting tripartite synapses with STED microscopy [PDF]
The concept of the tripartite synapse reflects the important role that astrocytic processes are thought to play in the function and regulation of neuronal synapses in the mammalian nervous system. However, many basic aspects regarding the dynamic interplay between pre- and postsynaptic neuronal structures and their astrocytic partners remain to be ...
A. Panatier, M. Arizono, U. V. Nagerl
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Adolescence is a developmental period that encompasses, but is not limited to, puberty and continues into early adulthood. During this period, maturation and refinement are observed across brain regions such as the prefrontal cortex (PFC), which is ...
Christopher Douglas Walker +4 more
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Information Encoding in Bursting Spiking Neural Network Modulated by Astrocytes
We investigated a mathematical model composed of a spiking neural network (SNN) interacting with astrocytes. We analysed how information content in the form of two-dimensional images can be represented by an SNN in the form of a spatiotemporal spiking ...
Sergey V. Stasenko, Victor B. Kazantsev
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Super-resolution imaging to reveal the nanostructure of tripartite synapses [PDF]
Abstract Even though neurons are the main drivers of information processing in the brain and spinal cord, other cell types are important to mediate adequate flow of information. These include electrically passive glial cells such as microglia and astrocytes, which recently emerged as active partners facilitating proper signal ...
Heller, Janosch Peter +1 more
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Regulation of dendritic spine morphogenesis and synapse formation by copines [PDF]
Primary rat hippocampal culture is a well established system to study molecular mechanisms occurring during synapse formation and maturation. By closer analysis of the temporal appearance of presynaptic Bassoon and the postsynaptic proteins SynGAP, PSD ...
Galic, Milos
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Astrocytes, the most abundant glial cells in the central nervous system (CNS), sense synaptic activity and respond through the release of gliotransmitters, a process mediated by intracellular Ca2+ level changes and SNARE-dependent mechanisms.
Daniela Sofia Abreu +11 more
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On tripartite common graphs [PDF]
A graph H is common if the number of monochromatic copies of H in a 2-edge-colouring of the complete graph Kn is asymptotically minimised by the random colouring.
Lee, Joonkyung +3 more
core
IntroductionWe previously discovered a pyridazine derivative compound series that can improve cognitive functions in mouse models of Alzheimer’s disease.
Emily Benson (16303147) +6 more
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Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis
Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder. Separate lines of evidence suggest that synapses and astrocytes play a role in the pathological mechanisms underlying ALS.
Matthew J. Broadhead +11 more
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Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) have proven themselves as one of the key in vivo techniques of modern neuroscience, allowing for unprecedented access to cellular manipulations in living animals.
Sophie H. Lee +3 more
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