Results 31 to 40 of about 85,493 (199)

Dissecting tripartite synapses with STED microscopy [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2014
The concept of the tripartite synapse reflects the important role that astrocytic processes are thought to play in the function and regulation of neuronal synapses in the mammalian nervous system. However, many basic aspects regarding the dynamic interplay between pre- and postsynaptic neuronal structures and their astrocytic partners remain to be ...
A. Panatier, M. Arizono, U. V. Nagerl
openaire   +2 more sources

Diverging Effects of Adolescent Ethanol Exposure on Tripartite Synaptic Development across Prefrontal Cortex Subregions

open access: yesCells, 2022
Adolescence is a developmental period that encompasses, but is not limited to, puberty and continues into early adulthood. During this period, maturation and refinement are observed across brain regions such as the prefrontal cortex (PFC), which is ...
Christopher Douglas Walker   +4 more
doaj   +1 more source

Information Encoding in Bursting Spiking Neural Network Modulated by Astrocytes

open access: yesEntropy, 2023
We investigated a mathematical model composed of a spiking neural network (SNN) interacting with astrocytes. We analysed how information content in the form of two-dimensional images can be represented by an SNN in the form of a spatiotemporal spiking ...
Sergey V. Stasenko, Victor B. Kazantsev
doaj   +1 more source

Super-resolution imaging to reveal the nanostructure of tripartite synapses [PDF]

open access: yesNeuronal Signaling, 2021
Abstract Even though neurons are the main drivers of information processing in the brain and spinal cord, other cell types are important to mediate adequate flow of information. These include electrically passive glial cells such as microglia and astrocytes, which recently emerged as active partners facilitating proper signal ...
Heller, Janosch Peter   +1 more
openaire   +5 more sources

Regulation of dendritic spine morphogenesis and synapse formation by copines [PDF]

open access: yes, 2006
Primary rat hippocampal culture is a well established system to study molecular mechanisms occurring during synapse formation and maturation. By closer analysis of the temporal appearance of presynaptic Bassoon and the postsynaptic proteins SynGAP, PSD ...
Galic, Milos
core   +1 more source

Astrocytes control hippocampal synaptic plasticity through the vesicular-dependent release of D-serine

open access: yesFrontiers in Cellular Neuroscience, 2023
Astrocytes, the most abundant glial cells in the central nervous system (CNS), sense synaptic activity and respond through the release of gliotransmitters, a process mediated by intracellular Ca2+ level changes and SNARE-dependent mechanisms.
Daniela Sofia Abreu   +11 more
doaj   +1 more source

On tripartite common graphs [PDF]

open access: yes, 2022
A graph H is common if the number of monochromatic copies of H in a 2-edge-colouring of the complete graph Kn is asymptotically minimised by the random colouring.
Lee, Joonkyung   +3 more
core  

Data_Sheet_1_Impact of a pyridazine derivative on tripartite synapse ultrastructure in hippocampus: a three-dimensional analysis.xlsx

open access: yes, 2023
IntroductionWe previously discovered a pyridazine derivative compound series that can improve cognitive functions in mouse models of Alzheimer’s disease.
Emily Benson (16303147)   +6 more
core   +1 more source

Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis

open access: yesActa Neuropathologica, 2022
Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder. Separate lines of evidence suggest that synapses and astrocytes play a role in the pathological mechanisms underlying ALS.
Matthew J. Broadhead   +11 more
openaire   +5 more sources

Comparative assessment of the effects of DREADDs and endogenously expressed GPCRs in hippocampal astrocytes on synaptic activity and memory

open access: yesFrontiers in Cellular Neuroscience, 2023
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) have proven themselves as one of the key in vivo techniques of modern neuroscience, allowing for unprecedented access to cellular manipulations in living animals.
Sophie H. Lee   +3 more
doaj   +1 more source

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