Results 51 to 60 of about 85,493 (199)
Frontiers in Computational Neuroscience, 2012 The complexity of the signaling network that underlies astrocyte-synapse interactions may seem discouraging when tackled from a theoretical perspective.
Maurizio eDe Pitta' +10 more
doaj +1 more source
Microglia: An Active Player in the Regulation of Synaptic Activity
Neural Plasticity, 2013 Synaptic plasticity is critical for elaboration and adaptation in the developing and developed brain. It is well established that astrocytes play an important role in the maintenance of what has been dubbed “the tripartite synapse”.
Kyungmin Ji +2 more
doaj +1 more source
Advanced Science, EarlyView.Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi +7 more
wiley +1 more source
A Digital Realization of Neuroglial Interaction Model and Its Network Structure
IEEE Access, 2022 Astrocyte cells, the most existing abundant cells in central nervous system, play an essential role in modulating the neuronal activities, information processing, and regulating the synaptic plasticity through calcium (Ca2+) fluctuations of ions ...
Mahsasadat Seyedbarhagh +2 more
doaj +1 more source
Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy
Advanced Science, EarlyView.ABSTRACT Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assembly.
Yuanqiang Lin +8 more
wiley +1 more source
, 2018 dissertationIn the past few decades, a revolution in our understanding of brain function has occurred based on demonstrations that astrocytes play critical roles in synaptic physiology. These findings led to the concept of the "tripartite synapse," which
Hasenoehrl, Meredith Gibbons
core
Differential segregation in a cell-cell contact interface: the dynamics of the immunological synapse [PDF]
, 2002 Receptor-ligand couples in the cell-cell contact interface between a T cell and an antigen-presenting cell form distinct geometric patterns and undergo spatial rearrangement within the contact interface.
Nigel John Burroughs +3 more
core +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
BMEMat, EarlyView.This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
About astroglia in the brain and pathology
Анналы клинической и экспериментальной неврологии, 2017 More than 140 years astrocytes were described as passive cellularelements of the brain, and their function was limited participationin providing trophic potential of neurons.
S. A. Goryaynov +5 more
doaj +1 more source
A mathematical model of the tripartite synapse: astrocyte-induced synaptic plasticity. [PDF]
J Biol Phys, 2012 42 pages, 14 figures, Journal of Biological Physics (to appear)
Tewari SG, Majumdar KK.
europepmc +5 more sources