Results 21 to 30 of about 1,246 (105)
tRNA-Derived Small RNAs: A Novel Regulatory Small Noncoding RNA in Renal Diseases
Kidney Diseases, 2023 Background: tRNA-derived small RNAs (tsRNAs) are an emerging class of small noncoding RNAs derived from tRNA cleavage. Summary: With the development of high-throughput sequencing, various biological roles of tsRNAs have been gradually revealed, including
Dan Li +6 more
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Cell Death Discovery, 2021 A large number of small non-coding RNAs derived from tRNAs, called tRNA-derived small RNA (tsRNAs), have been identified by high-throughput RNA sequencing of cell lines. Further research has revealed that they are not produced via random tRNA degradation,
Jing-tao Wen +5 more
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Journal of Cellular Physiology, 2020 AbstractDespite recent advances in targeted therapies, the molecular mechanisms driving breast cancer initiation, progression, and metastasis are minimally understood. Growing evidence indicate that transfer RNA (tRNA)‐derived small RNAs (tsRNA) contribute to biological control and aberrations associated with cancer development and progression.
Nicholas H. Farina +11 more
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Parasites & Vectors, 2021 Background Small non-coding RNAs play critical regulatory roles in post-transcription. However, their characteristics in Trichomonas vaginalis, the causative agent of human sexually transmitted trichomoniasis, still remain to be determined. Methods Small
Zhen-Sheng Wang +8 more
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Transfer RNAs-derived small RNAs and their application potential in multiple diseases
Frontiers in Cell and Developmental Biology, 2022 The role of tRNAs is best known as adapter components of translational machinery. According to the central dogma of molecular biology, DNA is transcribed to RNA and in turn is translated into proteins, in which tRNA outstands by its role of the cellular ...
Xiaohua Chu +7 more
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Digging out the biology properties of tRNA-derived small RNA from black hole
Frontiers in Genetics, 2023 An unique subclass of functional non-coding RNAs generated by transfer RNA (tRNA) under stress circumstances is known as tRNA-derived small RNA (tsRNA).
Hengmei Shi +7 more
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tRNA-derived small RNAs in plant response to biotic and abiotic stresses
Frontiers in Plant Science, 2023 tRNA-derived small RNAs (tsRNAs) represent a novel category of small non-coding RNAs and serve as a new regulator of gene expression at both transcriptional and post-transcriptional levels. Growing evidence indicates that tsRNAs can be induced by diverse
Chaojun Wang +5 more
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Transfer RNA-derived small RNAs (tsRNAs) in gastric cancer
Frontiers in Oncology, 2023 Transfer RNA-derived small RNAs (tsRNAs) are newly discovered noncoding RNAs (ncRNAs). According to the specific cleavage of nucleases at different sites of tRNAs, the produced tsRNAs are divided into tRNA-derived stress-inducible RNAs (tiRNAs) and tRNA ...
Lu Gan +3 more
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Transfer RNA-derived small RNA: an emerging small non-coding RNA with key roles in cancer
Experimental Hematology & Oncology, 2022 Transfer RNAs (tRNAs) promote protein translation by binding to the corresponding amino acids and transporting them to the ribosome, which is essential in protein translation.
Xinliang Gu +5 more
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tiRNAs: Insights into Their Biogenesis, Functions, and Future Applications in Livestock Research
Non-Coding RNA, 2022 Transfer RNA (tRNA)-derived small RNAs (tsRNAs) belong to a group of transfer ribonucleic acid (tRNA)-derived fragments that have recently gained interest as molecules with specific biological functions.
Fabio Sarais +3 more
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