Unconventional T Cells in IgA Nephropathy [PDF]
Kidney International ReportsZizhang Sheng, Nicholas J. Steers
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Human unconventional T cells in Plasmodium falciparum infection. [PDF]
Semin Immunopathol, 2020 Malaria is an old scourge of humankind and has a large negative impact on the economic development of affected communities. Recent success in malaria control and reduction of mortality seems to have stalled emphasizing that our current intervention tools need to be complemented by malaria vaccines.
Schmaler M +4 more
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Early-life imprinting of unconventional T cells and tissue homeostasis. [PDF]
Science, 2021 Atypical T cells take a different path Conventional T cells recognize peptides that are presented by polymorphic major histocompatibility complexes (MHCs). By contrast, many tissue-resident T cells, such as mucosal-associated invariant T cells, invariant natural killer T cells, and γδ T cells, respond to modified peptides and small molecules ...
Constantinides MG, Belkaid Y.
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Translating Unconventional T Cells and Their Roles in Leukemia Antitumor Immunity [PDF]
Journal of Immunology Research, 2021 Recently, cell-mediated immune response in malignant neoplasms has become the focus in immunotherapy against cancer. However, in leukemia, most studies on the cytotoxic potential of T cells have concentrated only on T cells that recognize peptide ...
Nilberto Dias de Araújo +8 more
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Mechanisms of Bacterial Superinfection Post-influenza: A Role for Unconventional T Cells [PDF]
Frontiers in Immunology, 2019 Despite the widespread application of vaccination programs and antiviral drug treatments, influenza viruses are still among the most harmful human pathogens.
Christophe Paget +6 more
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Patients With Immunoglobulin A Nephropathy Show Abnormal Frequencies of B Cell Subsets, Unconventional T Cells, and High Levels of Galactose-Deficient IgA1–Coated Gut Bacteria [PDF]
Kidney International ReportsIntroduction: Mucosal inflammation is involved in the pathophysiology of immunoglobulin-A nephropathy (IgAN); however, peripheral immune phenotype analyses of patients with IgAN often do not include unconventional T cells, the major subset in mucosal ...
Micaela Gentile +20 more
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The Influence of Innate Lymphoid Cells and Unconventional T Cells in Chronic Inflammatory Lung Disease [PDF]
Frontiers in Immunology, 2019 The lungs are continuously subjected to environmental insults making them susceptible to infection and injury. They are protected by the respiratory epithelium, which not only serves as a physical barrier but also a reactive one that can release ...
Jessica G. Borger +3 more
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Developmental trajectory of unconventional T cells of the cynomolgus macaque thymus [PDF]
HeliyonAs nonhuman primates are immunologically the closest model to humans, a comprehensive understanding of T-cell development in these species is crucial. However, the differentiation pathways in which thymocytes participate, along with their heterogeneity ...
Sung Min Choi +2 more
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Tuberculosis preventive therapy in postpartum women with HIV modifies M. tuberculosis-specific and nonspecific immune responses [PDF]
Frontiers in ImmunologyBackgroundTuberculosis (TB) has significant morbidity in pregnant and postpartum women with HIV (pregnant and PPWWHIV). TB preventive therapy (TPT) is recommended in pregnant and PPWWHIV with documented or presumed latent TB infection (LTBI).
Damayanti Yengkhom +10 more
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The Emerging Roles and Therapeutic Potential of Unconventional T Cells in Sepsis [PDF]
Journal of Inflammation ResearchShuaipeng Gu,1 Peidong Zhang,1 Cong Zhang,1 Tingxuan Tang,2 Teding Chang,1 Liming Dong,1 Wei Gao,1,* Zhaohui Tang1,* 1Department of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, Tongji Hospital, Tongji ...
Gu S +7 more
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