Results 51 to 60 of about 33,130 (117)

Increasing Stress to Induce Apoptosis in Pancreatic Cancer via the Unfolded Protein Response (UPR). [PDF]

Int J Mol Sci, 2022
Botrus G, Miller RM, Uson Junior PLS, Kannan G, Han H, Von Hoff DD.   +5 more
europepmc   +1 more source

Interplay between autophagy, the unfolded protein response and the cytoplasmic heat stress response during heat stress in maize

BMC Plant Biology
Background High temperatures can substantially reduce plant survival and reproduction, and therefore decrease crop productivity. Plants activate several pathways in response to high temperatures, including the endoplasmic reticulum (ER) unfolded protein ...
Jie Tang, Vishadinie Jayasinghe, Zhaoxia Li, Diane C. Bassham   +3 more
doaj   +1 more source

Thioredoxin‐interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress

EMBO Molecular Medicine, 2014
The endoplasmic reticulum (ER) is responsible for protein folding, modification, and trafficking. Accumulation of unfolded or misfolded proteins represents the condition of ER stress and triggers the unfolded protein response (UPR), a key mechanism ...
Samuel Lee, Soo Min Kim, James Dotimas, Letitia Li, Edward P Feener, Stephan Baldus, Ronald B Myers, William A Chutkow, Parth Patwari, Jun Yoshioka, Richard T Lee   +10 more
doaj   +1 more source

Drosophila Unfolded Protein Response (UPR) Assays In Vitro and In Vivo. [PDF]

Methods Mol Biol, 2022
Katow H, Vasudevan D, Ryoo HD.
europepmc   +1 more source

Regulation of the ER stress response by a mitochondrial microprotein

Nature Communications, 2019
Cells trigger an unfolded protein response (UPR) in the endoplasmic reticulum, but its regulation by mitochondria is unclear. Here, the authors report a 54-residue microprotein PIGBOS that participates in inter-organelle contact between the endoplasmic ...
Qian Chu, Thomas F. Martinez, Sammy Weiser Novak, Cynthia J. Donaldson, Dan Tan, Joan M. Vaughan, Tina Chang, Jolene K. Diedrich, Leo Andrade, Andrew Kim, Tong Zhang, Uri Manor, Alan Saghatelian   +12 more
doaj   +1 more source

Immunogenic landscape and risk score prediction based on unfolded protein response (UPR)-related molecular subtypes in hepatocellular carcinoma. [PDF]

Front Immunol, 2023
Guo H, Zhang S, Zhang B, Shang Y, Liu X, Wang M, Wang H, Fan Y, Tan K.   +8 more
europepmc   +1 more source

New insights into the unfolded protein response (UPR)-anterior gradient 2 (AGR2) pathway in the regulation of intestinal barrier function in weaned piglets. [PDF]

Anim Nutr, 2023
Zhang F, Chen M, Liu X, Ji X, Li S, Jin E.   +5 more
europepmc   +1 more source

Editorial: Unfolded protein response (UPR): An impending target for multiple neurological disorders. [PDF]

Front Aging Neurosci, 2022
Jan AT, Rahman S, Ahmad K, Minakshi R.
europepmc   +1 more source

Diclofenac Diminished the Unfolded Protein Response (UPR) Induced by Tunicamycin in Human Endothelial Cells. [PDF]

Molecules, 2022
Sokołowska P, Siatkowska M, Jóźwiak-Bębenista M, Komorowski P, Koptas M, Kowalczyk E, Wiktorowska-Owczarek A.   +6 more
europepmc   +1 more source

Inhibition of PERK Kinase, an Orchestrator of the Unfolded Protein Response (UPR), Significantly Reduces Apoptosis and Inflammation of Lung Epithelial Cells Triggered by SARS-CoV-2 ORF3a Protein. [PDF]

Biomedicines, 2023
Keramidas P, Papachristou E, Papi RM, Mantsou A, Choli-Papadopoulou T.   +4 more
europepmc   +1 more source