Results 61 to 70 of about 33,130 (117)

Cell death induction in <i>Aspergillus fumigatus</i>: accentuating drug toxicity through inhibition of the unfolded protein response (UPR). [PDF]

Curr Res Microb Sci, 2022
Guirao-Abad JP, Weichert M, Askew DS.
europepmc   +1 more source

The mitochondrial unfolded protein response (UPR^mt) protects against osteoarthritis. [PDF]

Exp Mol Med, 2022
Zhou Z, Lu J, Yang M, Cai J, Fu Q, Ma J, Zhu L.   +6 more
europepmc   +1 more source

Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease. [PDF]

Cancers (Basel), 2021
Chen C, Wu H, Ye H, Tortajada A, Rodríguez-Perales S, Torres-Ruiz R, Vidal A, Peligros MI, Reissing J, Bruns T, Mohamed MR, Zheng K, Lujambio A, Iraburu MJ, Colyn L, Latasa MU, Arechederra M, Fernández-Barrena MG, Berasain C, Vaquero J, Bañares R, Nelson LJ, Trautwein C, Davis RJ, Martinez-Naves E, Nevzorova YA, Villanueva A, Avila MA, Cubero FJ.   +28 more
europepmc   +1 more source

Emerging mechanisms of the unfolded protein response in therapeutic resistance: from chemotherapy to Immunotherapy

Cell Communication and Signaling
The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) causes ER stress and activates the unfolded protein response (UPR). As an adaptive cellular response to hostile microenvironments, such as hypoxia, nutrient deprivation,
Jiang He, You Zhou, Lunquan Sun
doaj   +1 more source

ONC201 induces the unfolded protein response (UPR) in high- and low-grade ovarian carcinoma cell lines and leads to cell death regardless of platinum sensitivity. [PDF]

Cancer Med, 2021
Rumman M, Buck S, Polin L, Dzinic S, Boerner J, Winer IS.   +5 more
europepmc   +1 more source

Dysregulation of the unfolded protein response (UPR) in the dorsolateral prefrontal cortex in elderly patients with schizophrenia. [PDF]

Mol Psychiatry, 2021
Kim P, Scott MR, Meador-Woodruff JH.
europepmc   +1 more source

The mitochondrial unfolded protein response (UPR^mt): shielding against toxicity to mitochondria in cancer. [PDF]

J Hematol Oncol, 2022
Inigo JR, Chandra D.
europepmc   +1 more source

Hijacking the unfolded protein response (UPR) pathway: Balancing viral infection and host cell survival. [PDF]

J Biol Chem
Chen H, Liu D, Hua J, Wu M, Hua Y, Feng C, He Z, Moffett P, Zhang K.   +8 more
europepmc   +1 more source

Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia. [PDF]

Cell Mol Biol Lett, 2020
Bartoszewska S, Collawn JF.
europepmc   +1 more source

An unfolded protein response (UPR)-signature regulated by the NFKB-miR-29b/c axis fosters tumor aggressiveness and poor survival in bladder cancer. [PDF]

Front Mol Biosci
Zhang J, Fan X, Chen Y, Han Y, Yu W, Zhang S, Yang B, Zhang J, Chen Y.   +8 more
europepmc   +1 more source