Results 21 to 30 of about 672 (110)
Frontiers in Immunology, 2023 Dendritic cells (DC) play a crucial role in generating and maintaining antiviral immunity. While DC are implicated in the antiviral defense by inducing T cell responses, they can also become infected by Cytomegalovirus (CMV).
Julia Cecilia Madela-Mönchinger +9 more
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XCR1 is differentially expressed in brain metastatic human breast cancer.
, 2021 Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans ...
Shahan Mamoor
core +1 more source
Die Expression des Chemokinrezeptors XCR1 kennzeichnet kreuzpräsentierende dendritische Zellen der Maus und des Menschen [PDF]
, 2013 Bei der Kreuzpräsentation durch dendritische Zellen (DC) werden extrazelluläre Antigene in den MHC I-Präsentationsweg eingeschleust und CD8+ T-Zellen präsentiert. Bisher werden die kreuzpräsentierenden DC der Maus durch die Expression der Moleküle CD8 in
Bachem, Annabell
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iScience, 2021 Summary: Successful immune responses rely on a regulated delivery of the right signals to the right cells at the right time. Here we show that natural killer (NK) and dendritic epidermal γδ T cells (DETCs) use similar mechanisms to spatiotemporally ...
Sonia Ghilas +7 more
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Immunotherapy of chronic virus infections : Exhausted CD8+ T cell subsets are differentially regulated by XCR1 + DC [PDF]
, 2022 The contribution of cross-presenting XCR1+ dendritic cells (DC) in maintaining T cell function during exhaustion and immuno-therapeutic interventions of chronic infections remains poorly characterized.
Domenjó Vila, Eva
core +1 more source
Expression and function of the chemokine receptor XCR1 on murine CD8 + DC [PDF]
, 2010 In dieser Arbeit wurde die Expression von XCR1 in B6XCR1lacZ+/+ Reporter Mäusen charakterisiert, die β-Galaktosidase unter der Kontrolle des XCR1-Promotors exprimieren.
Mora, Ahmed
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Lung dendritic cells (DCs) are divided into two major populations, which include CD103+XCR1+ cDC1s and CD11b+Sirpα+ cDC2s. The maintenance of their relative proportions is dynamic and lung inflammation, such as caused by exposure to lipopolysaccharide ...
Julyanne Brassard +7 more
doaj +1 more source
PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis
Nature Communications, 2021 Dendritic cells initiate and regulate adaptive immunity and differ according to gut anatomical location. Here the authors show that DC residing in the upper and lower intestines show differential PD-L1 and XCR1 expression and drive specific T cell ...
Thais G. Moreira +18 more
doaj +1 more source
Frontiers in Immunology, 2018 The chemokine receptor XCR1 is known to be selectively expressed by cross-presenting dendritic cells (DCs), while its ligand XCL1/lymphotactin is mainly produced by activated CD8+ T cells and natural killer cells.
Kazuhiko Matsuo +10 more
doaj +1 more source
Genetic variants associated with SARS-CoV-2 infection also affect lung function and asthma severity
Heliyon, 2023 Background: Host genetic factors may be associated with COVID-19 unfavourable outcomes. The first genome-wide association study (GWAS) conducted in individuals with respiratory failure due to COVID-19 revealed susceptibility loci close to six genes ...
Milca de Jesus Silva +8 more
doaj +1 more source