Results 21 to 30 of about 7,168 (188)

Chemokine Receptor Profiles as Predictors of Survival and Early Progression in Follicular Lymphoma [PDF]

eJHaem
Objective: Classical follicular lymphoma (FL) is a heterogeneous malignancy. Early progression within 24 months (POD24) is linked to poor outcomes. However, precise risk stratification remains unclear.
Antonella Zupo, Katrin Pansy, Lukas Gaksch, Julia Waldhart, Andrea Brunner, Johanna Strobl, Marta Szmyra‐Polomka, Sandra Haingartner, Peter V. Tomazic, Hildegard T. Greinix, Barbara Uhl, Julia Feichtinger, Georg Stary, Johannes Haybaeck, Fotini Rosi Vagena, Martin Zacharias, Christine Beham‐Schmid, Peter Neumeister, Katharina Theresa Prochazka, Alexander J. A. Deutsch   +19 more
doaj   +2 more sources

CAR-T cells and CAR-Tregs targeting conventional type-1 dendritic cell suppress experimental autoimmune encephalomyelitis

Frontiers in Immunology, 2023
Conventional type 1 dendritic cells (DC1) contribute to the development of pathogenic T helper type 1 (Th1) cells in part via the production of the proinflammatory cytokine interleukin-12.
Cody D. Moorman, Sherman Yu, Carlos G. Briseno, Hyewon Phee, Anupama Sahoo, Ambika Ramrakhiani, Ashutosh Chaudhry   +6 more
doaj   +1 more source

Cloning of Grass Carp Chemokine XC Receptor 1 (XCR1) Gene and Evaluation of Its Expression in Various Organs after GCRV Infection

Fishes, 2022
Interaction between the chemokine receptor XCR1 and its ligand is closely related to the immune function in animals; however, there are only a few reports on role of XCR1 in the immune system of fish. We aimed to analyze the expression of XCR1 in various
Hailuo Yu, Yi Liu, Tiaoyi Xiao, Hongquan Wang, Baohong Xu   +4 more
doaj   +1 more source

A hitchhiker's guide to myeloid cell subsets: practical implementation of a novel mononuclear phagocyte classification system [PDF]

, 2015
The classification of mononuclear phagocytes as either dendritic cells or macrophages has been mainly based on morphology, the expression of surface markers, and assumed functional specialization.
Adams, Ajami, Ajami, Bachem, Bachem, Bain, Bain, Balan, Becker, Benson, Bogunovic, Breton, Caton, Caux, Cheong, Chorro, Chou, Cisse, Contreras, Coombes, Crozat, Crozat, Crozat, Desch, Diao, Durand, Edelson, Epelman, Gao, Gatto, Gautier, Geissmann, Geurtsvankessel, Ghosh, Ginhoux, Ginhoux, Ginhoux, Gomez Perdiguero, Grajales-Reyes, Guilliams, Guilliams, Guilliams, Guilliams, Guilliams, Guilliams, Gurka, Hacker, Hashimoto, Helft, Hettinger, Hildner, Hoeffel, Hoeffel, Inaba, Jackson, Jaitin, Jakubzick, Jang, Janssen, Jha, Karsunky, Kashiwada, Kuipers, Lavin, Lee, Lewis, McKenna, Merad, Miller, Molawi, Murray, Naik, Naik, Naik, Ohl, Onai, Onai, Palucka, Persson, Plantinga, Poltorak, Poulin, Pulendran, Randolph, Reynolds, Robbins, Sallusto, Salomon, Satpathy, Saunders, Schiavoni, Schlitzer, Schlitzer, Schraml, Schulz, Scott, Serbina, Shalek, Siddiqui, Sun, Suzuki, Swirski, Tailor, Tamoutounour, Tamoutounour, Tamura, Tussiwand, van Furth, van Furth, Varol, Varol, Varol, Vu Manh, Vu Manh, Vu Manh, Waskow, Wimmers, Wu, Xu, Xue, Yamasaki, Yona, Yona, Zigmond   +123 more
core   +10 more sources

Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells

Frontiers in Immunology, 2023
A single population of interferon-regulatory factor 8 (Irf8)-dependent conventional dendritic cell (cDC type1) is considered to be responsible for both immunogenic and tolerogenic responses depending on the surrounding cytokine milieu. Here, we challenge
Adan Chari Jirmo, Adan Chari Jirmo, Ruth Grychtol, Ruth Grychtol, Svenja Gaedcke, Bin Liu, Stephanie DeStefano, Christine Happle, Christine Happle, Olga Halle, Olga Halle, Joao T. Monteiro, Joao T. Monteiro, Anika Habener, Anika Habener, Oliver D. Breiholz, David DeLuca, Gesine Hansen, Gesine Hansen, Gesine Hansen   +19 more
doaj   +1 more source

Investigating Evolutionary Conservation of Dendritic Cell Subset Identity and Functions [PDF]

, 2015
International audienceDendritic cells (DCs) were initially defined as mononuclear phagocytes with a dendritic morphology and an exquisite efficiency for naïve T-cell activation.
Bertho, Nicolas, Dalod, Marc, Hosmalin, Anne, Schwartz-Cornil, Isabelle, Vu Manh, Thien-Phong   +4 more
core   +14 more sources

Overexpression of chemokine receptor lymphotactin receptor 1 has prognostic value in clear cell renal cell carcinoma

Molecular Genetics & Genomic Medicine, 2021
Background Clear cell renal cell carcinoma (ccRCC) is an aggressive subtype of renal cell carcinoma. X‐C motif chemokine receptor 1 (XCR1) exerts important roles in tumor progression; however, its role in ccRCC is unclear.
Xian Chang, Ya Cao, Wan‐Lei Fu, Xue‐Feng Tang, Ya‐Li Wang, Yang‐Fan Lv, Qiao‐Nan Guo   +6 more
doaj   +1 more source

Harnessing human cross-presenting CLEC9A+XCR1+ dendritic cells for immunotherapy [PDF]

Frontiers in Immunology, 2014
Dendritic cells (DC) are professional antigen presenting cells (APCs) that play a pivotal role in the induction and regulation of immune responses, including the induction of cytotoxic T lymphocyte (CTL) responses. They are an important focus for the development of vaccines against cancers and many pathogens, including HIV and malaria, where CTL ...
Kirsteen eTullett, Kirsteen eTullett, Kirsteen eTullett, Mireille eLahoud, Mireille eLahoud, Kristen J Radford, Kristen J Radford   +6 more
doaj   +5 more sources

Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis [PDF]

Scientific Reports, 2016
Abstract Intestinal immune homeostasis requires dynamic crosstalk between innate and adaptive immune cells. Dendritic cells (DCs) exist as multiple phenotypically and functionally distinct sub-populations within tissues, where they initiate immune responses and promote homeostasis. In the gut, there exists a minor
Ohta, T, Sugiyama, M, Hemmi, H, Yamazaki, C, Okura, S, Sasaki, I, Fukuda, Y, Orimo, T, Ishii, K.J, Hoshino, K, Ginhoux, F, Kaisho, T   +11 more
openaire   +2 more sources

Up-regulation of XCR1 expression in rheumatoid joints [PDF]

Rheumatology, 2004
Chemokine receptor-positive cells play a crucial role in controlling synovitis in rheumatoid arthritis (RA). We studied 16 chemokine receptors of the CC, CXC, CX3C and C families by analysing venous blood and synovial fluid samples and synovial tissues from RA patients.Mononuclear cells (MNCs) in paired synovial fluid and venous blood samples from 7 RA
C-R, Wang, M-F, Liu, Y-H, Huang, H-C, Chen   +3 more
openaire   +2 more sources