Results 31 to 40 of about 2,779,849 (194)
The majority of A-to-I RNA editing is not required for mammalian homeostasis
Genome Biology, 2019 Background Adenosine-to-inosine (A-to-I) RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sites across mammalian transcriptomes.
Alistair M. Chalk +3 more
doaj +1 more source
Epitranscriptomic investigation of myopia-associated RNA editing in the retina
Frontiers in Neuroscience, 2023 Myopia is one of the most common causes of vision loss globally and is significantly affected by epigenetics. Adenosine-to-inosine (A-to-I RNA) editing is an epigenetic process involved in neurological disorders, yet its role in myopia remains ...
Xu-Bin Pan +24 more
doaj +1 more source
Publica aut peri! The Releasing and Distribution of Roman Books [PDF]
, 2007 This outline of our knowledge of the process of releasing literature in late republican and early imperial Rome addresses the nature of the recitations, the question of ‘publishing’ and distribution of books, from Atticus to Pliny the Younger.
Jon Wikene Iddeng
core +1 more source
RNA editing signature during myeloid leukemia cell differentiation [PDF]
, 2017 Adenosine deaminases acting on RNA (ADARs) are key proteins for hematopoietic stem cell self-renewal and for survival of differentiating progenitor cells. However, their specific role in myeloid cell maturation has been poorly investigated.
A Athanasiadis +48 more
core +2 more sources
Increased A-to-I RNA editing in atherosclerosis and cardiomyopathies
PLOS Computational Biology, 2023 Adenosine-to-inosine RNA editing is essential to prevent undesired immune activation. This diverse process alters the genetic content of the RNA and may recode proteins, change splice sites and miRNA targets, and mimic genomic mutations. Recent studies have associated or implicated aberrant editing with pathological conditions, including cancer ...
Tomer D. Mann +3 more
openaire +4 more sources
Systematically Characterizing A-to-I RNA Editing Neoantigens in Cancer [PDF]
Frontiers in Oncology, 2020 A-to-I RNA editing can contribute to the transcriptomic and proteomic diversity of many diseases including cancer. It has been reported that peptides generated from RNA editing could be naturally presented by human leukocyte antigen (HLA) molecules and elicit CD8+ T cell activation.
Chi Zhou +4 more
openaire +3 more sources
Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections
BMC Genomics, 2023 Background RNA editing is a process that increases transcriptome diversity, often through Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of adenosine to inosine.
Benjamin Wales-McGrath +2 more
doaj +1 more source
Microbiology Spectrum, 2021 Iron is an essential element for the growth and survival of pathogenic bacteria; however, it is not fully understood how bacteria sense and respond to iron deficiency or excess. In this study, we show that xfeA in Xanthomonas oryzae pv.
Wenhan Nie +14 more
doaj +1 more source
A-to-I RNA editing in the earliest-diverging Eumetazoan phyla [PDF]
, 2017 © The Author(s), 2017. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Molecular Biology and Evolution 34 (2017): 1890-1901, doi:10.1093/molbev/msx125.The highly conserved ...
Alon, Shahar +7 more
core +1 more source
Transcriptome analysis identification of A-to-I RNA editing in granulosa cells associated with PCOS
Frontiers in Endocrinology, 2023 BackgroundPolycystic ovary syndrome (PCOS) is a complex, multifactor disorder in women of reproductive age worldwide. Although RNA editing may contribute to a variety of diseases, its role in PCOS remains unclear.MethodsA discovery RNA-Seq dataset was ...
Fan-Sheng Kong +19 more
doaj +1 more source