Results 71 to 80 of about 66,837 (297)

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

The Chaperonin TRiC/CCT Inhibitor HSF1A Protects Cells from Intoxication with Pertussis Toxin

Toxins
Pertussis toxin (PT) is a bacterial AB5-toxin produced by Bordetella pertussis and a major molecular determinant of pertussis, also known as whooping cough, a highly contagious respiratory disease.
Jinfang Jia, Manuel Zoeschg, Holger Barth, Arto T. Pulliainen, Katharina Ernst   +4 more
doaj   +1 more source

Potential roles of CCR5(+) CCR6(+) dendritic cells induced by nasal ovalbumin plus Flt3 ligand expressing adenovirus for mucosal IgA responses. [PDF]

PLoS ONE, 2013
We assessed the role of CCR5(+)/CCR6(+)/CD11b(+)/CD11c(+) dendritic cells (DCs) for induction of ovalbumin (OVA)-specific antibody (Ab) responses following mucosal immunization.
Yoshiko Fukuyama, Daisuke Tokuhara, Shinichi Sekine, Kazuyoshi Aso, Kosuke Kataoka, Julia Davydova, Masato Yamamoto, Rebekah S Gilbert, Yuka Tokuhara, Keiko Fujihashi, Jun Kunisawa, Yoshikazu Yuki, Hiroshi Kiyono, Jerry R McGhee, Kohtaro Fujihashi   +14 more
doaj   +1 more source

Sustainable Electrochemical Synthesis of High‐Quality MXenes: Mechanistic Insights, Applications, Challenges, and Technological Prospects

Advanced Functional Materials, EarlyView.
Electrochemical etching provides an eco‐friendly alternative to hazardous HF methods for MXene production. This approach facilitates the selective isolation of the A‐layer from MAX phases with tunable surface terminations. Controlling voltage, electrolytes, temperature, and duration enables the optimal structural integrity. Nevertheless, existing scale
Jagdeep Singh, Madhusudhana M Devadiga, Santosh K. Tiwari, AS Dhaliwal, Gurpreet Singh Selopal   +4 more
wiley   +1 more source

Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin [PDF]

, 2013
Buruli ulcer (BU), caused by Mycobacterium ulcerans is a chronic necrotizing skin disease. It usually starts with a subcutaneous nodule or plaque containing large clusters of extracellular acid-fast bacilli.
Kwabena Quenin-Fosu, Gerd Pluschke, Newman Mercy, Ruf, Marie-Thérèse, Cynthia Kwakye-Maclean (349465), Grace S. Kpeli, Asan-Ampah, Kobina, Mercy Newman (409617), Kwabena Quenin-Fosu (335716), Marie-Thérèse Ruf (2280196), Isaac Lamptey, Kwakye-Maclean Cynthia, Mercy Newman, Albert Paintsil (409614), Kpeli Grace S., Cynthia Kwakye-Maclean, Grace S. Kpeli (409612), Isaac Lamptey (409615), Dorothy Yeboah-Manu, Benjamin Anku, Pluschke, Gerd, Yeboah-Manu, Dorothy, Evelyn Owusu-Mireku, Marie-Thérèse Ruf, Dorothy Yeboah-Manu (120059), Grace S Kpeli, Anku Benjamin, Albert Paintsil, Owusu-Mireku Evelyn, Evelyn Owusu-Mireku (409613), Quenin-Fosu Kwabena, Owusu-Mireku, Evelyn, Lamptey, Isaac, Paintsil, Albert, Quenin-Fosu, Kwabena, Benjamin Anku (409616), Ruf Marie-Thérèse, Pluschke Gerd, Kwakye-Maclean, Cynthia, Gerd Pluschke (7855), Kobina Asan-Ampah (335715), Anku, Benjamin, Asan-Ampah Kobina, Yeboah-Manu Dorothy, Paintsil Albert, Kpeli, Grace S., Newman, Mercy, Lamptey Isaac, Kobina Asan-Ampah   +48 more
core   +1 more source

High Affinity Binding of Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1) to Lu/BCAM Adhesion Glycoprotein

Toxins, 2017
The protein toxin Cytotoxic Necrotizing Factor 1 (CNF1) is a major virulence factor of pathogenic Escherichia coli strains. It belongs to a family of single chain AB-toxins, which enter mammalian cells by receptor-mediated endocytosis.
Franziska Reppin, Sylvie Cochet, Wassim El Nemer, Günter Fritz, Gudula Schmidt   +4 more
doaj   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

WORLDWIDE SURVEY OF CLINICIAN PRACTICE ON USE OF ADJUNCTIVE THERAPIES FOLLOWING BOTULINUM TOXIN INJECTION FOR SPASTICITY

, 2022
OBJECTIVE: Non-pharmacological adjunctive therapies can be used alongside botulinum toxin injection to enhance its efficacy. The objective of this global study was to determine the current practice and perception among clinicians of the use of adjunctive
Erika Suzigan, TEIXEIRA, Joao Eduardo Marten, SCHINWELSKI, Michal, Fabienne Schillebeeckx, Mills, Patricia B, SCHILLEBEECKX, Fabienne, Stephen Ashford, Joao Eduardo Marten Teixeira, Nicolas Bayle, Jorge Jacinto, NAYAR, Meenakshi, Alvin Ip, JACINTO, Jorge, Alvin, I.P., Patricia B. Mills, CHEMELLO, Elena, IP, Alvin, SUZIGAN, Erika, Thierry Deltombe, MILLS, Patricia B., Elena Chemello, Marten Teixeira, Joao Eduardo, Michal Schinwelski, Mills, Patricia, Ashford, Stephen; id_orcid, DELTOMBE, Thierry, BAYLE, Nicolas, ASHFORD, Stephen, Meenakshi Nayar   +28 more
core   +1 more source

Laboratory diagnostic methods for clostridioides difficile infection

One Health & Risk Management, 2023
Introduction. Clostridioides difficile is an anaerobic gram-positive, sporeforming, toxin-producing bacillus that is transmitted among humans through the fecal-oral route, as a result of ingestion of spores. Colonization of C.
Anastasia ALEXANDROV
doaj  

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source