Results 91 to 100 of about 26,813 (237)
The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants
Basic & Clinical Pharmacology & ToxicologyABSTRACT This scoping review investigates the association between ABCB1 polymorphisms and antidepressant efficacy in humans. A systematic search identified 630 records, of which 58 met the inclusion criteria, resulting in 42 unique studies (five randomised controlled trials (
Sofie Voss Thorsen +3 more
openaire +3 more sources
Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling
Cytopathology, EarlyView.Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu +3 more
wiley +1 more source
, 2012 Daniel T Barratt1, Janet K Coller1, Richard Hallinan2, Andrew Byrne2, Jason M White1, David JR Foster3, Andrew A Somogyi1,41Discipline of Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, South Australia; 2The Byrne Surgery ...
Coller JK +6 more
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Effect of fentanyl on the expression of ABCB1 in ABCB1-overexpressing cell lines.
, 2015 Expression of ABCB1 was measured from: (A) equal amounts of total cell lysates were loaded and detected by Western blot; (B) the mRNA level of ABCB1 was determined by RT-PCR; (C) summary data from the mRNA level of ABCB1 determined by RT real-time-PCR ...
Wan Huang (600038) +7 more
core +1 more source
Association between ABCB1 Gene Polymorphisms and Labor Analgesia in Primiparas
Clinical and Experimental Obstetrics & GynecologyBackground: The present study aimed to explore the association of ATP-binding cassette B1 (ABCB1)/multiple drug resistance 1 (MDR1) gene polymorphisms (rs1128503 and rs1045642) with labor analgesia in primiparas.
Wei Li +6 more
doaj +1 more source
Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response
The FEBS Journal, EarlyView.Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril +2 more
wiley +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang +10 more
wiley +1 more source
Lipid Regulation of the ABCB1 and ABCG2 Multidrug Transporters [PDF]
, 2015 This chapter deals with the interactions of two medically important multidrug ABC transporters (MDR-ABC), ABCB1 and ABCG2, with lipid molecules. Both ABCB1 and ABCG2 are capable of transporting a wide range of hydrophobic drugs and xenobiotics and are involved in cancer chemotherapy resistance.
Hegedüs, Csilla +4 more
openaire +2 more sources
The effect of ABCB1 polymorphisms on the outcome of breast cancer treatment
, 2016 Sonam Tulsyan,1 Rama Devi Mittal,2 Balraj Mittal1 1Department of Genetics, 2Department of Urology and Renal Transplant, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaAbstract: The ABCB1 gene encodes a permeability glycoprotein ...
Tulsyan S, Mittal B, Mittal RD
core
Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson’s disease [PDF]
, 2015 BACKGROUND: Studies suggested that variants in the ABCB1 gene encoding P-glycoprotein, a xenobiotic transporter, may increase susceptibility to pesticide exposures linked to Parkinson's Disease (PD) risk.
Sinsheimer, Janet S +6 more
core +1 more source