Results 51 to 60 of about 47,553 (202)

Alphaherpesvirus: isolation, identification, partial characterisation, associated pathologic findings, and epidemiology in beluga whales (Delphinapterus leucas) in Alaska and Arctic Canada

Arctic Science, 2018
Live, dead stranded, and harvested belugas (Delphinapterus leucas) in Alaska and the western Canadian Arctic were screened for viruses utilizing a primary beluga cell line. Samples consisted of swabs from blowhole, anus, and genital tract.
Ole Nielsen, Kathleen A. Burek-Huntington, Lisa L. Loseto, Maria Morell, Carlos H. Romero   +4 more
doaj   +1 more source

Alphaherpesvirus Infection Disrupts Mitochondrial Transport in Neurons [PDF]

Cell Host & Microbe, 2012
Mitochondria are dynamic organelles that are essential for cellular metabolism but can be functionally disrupted during pathogen infection. In neurons, mitochondria are transported on microtubules via the molecular motors kinesin-1 and dynein and recruited to energy-requiring regions such as synapses.
Kramer, Tal, Enquist, Lynn W.
openaire   +2 more sources

Several Alphaherpesviruses Interact Similarly with the NF-κB Pathway and Suppress NF-κB-Dependent Gene Expression

Microbiology Spectrum, 2023
Alphaherpesvirus infection is associated with attenuation of different aspects of the host innate immune response that is elicited to confine primary infections at the mucosal epithelia.
Nicolás Romero, Alexander Tishchenko, Ruth Verhamme, Shelly M. Wuerzberger-Davis, Cliff Van Waesberghe, Hans J. Nauwynck, Shigeki Miyamoto, Herman W. Favoreel   +7 more
doaj   +1 more source

A Common Neuronal Response to Alphaherpesvirus Infection [PDF]

Journal of Neuroimmune Pharmacology, 2010
Alphaherpesviruses are a subfamily of the Herpesviridae that can invade the nervous system and establish either lytic or latent infections. The establishment of latent infection can occur only in neurons, indicating a unique virus-host interaction in these cells.
Moriah L, Szpara, Oren, Kobiler, Lynn W, Enquist   +2 more
openaire   +2 more sources

Infectious Disease Outbreak Associated With Supplementary Feeding of Semi-domesticated Reindeer

Frontiers in Veterinary Science, 2019
Supplementary winter feeding of semi-domesticated reindeer (Rangifer tarandus tarandus) has become more common in Sweden and Norway due to reindeer pasture fragmentation and climatic conditions.
Morten Tryland, Ingebjørg H. Nymo, Ingebjørg H. Nymo, Javier Sánchez Romano, Torill Mørk, Jörn Klein, Ulrika Rockström   +6 more
doaj   +1 more source

MORC3, a component of PML nuclear bodies, has a role in restricting herpes simplex virus type 1 and human cytomegalovirus [PDF]

, 2016
We previously reported that MORC3, a protein associated with promyelocytic leukemia nuclear bodies (PML NBs), is a target of HSV-1 ICP0 mediated degradation.
Everett, Roger, Orr, Anne, Sloan, Elizabeth   +2 more
core   +1 more source

Regulation of alphaherpesvirus protein via post-translational phosphorylation

Veterinary Research, 2022
AbstractAn alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release. After infecting the host, a virus eliminates unfavourable factors via multiple mechanisms to escape or suppress the attack of the host immune ...
Tong Zhou, Mingshu Wang, Anchun Cheng, Qiao Yang, Bin Tian, Ying Wu, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao, Xuming Ou, Sai Mao, Di Sun, Shaqiu Zhang, Dekang Zhu, Juan Huang, Qun Gao, Yanling Yu, Ling Zhang   +18 more
openaire   +3 more sources

The Role of VP16 in the Life Cycle of Alphaherpesviruses

Frontiers in Microbiology, 2020
The protein encoded by the UL48 gene of alphaherpesviruses is named VP16 or alpha-gene-transactivating factor (α-TIF). In the early stage of viral replication, VP16 is an important transactivator that can activate the transcription of viral immediate ...
Dengjian Fan, Dengjian Fan, Dengjian Fan, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Renyong Jia, Renyong Jia, Renyong Jia, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Dekang Zhu, Dekang Zhu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Xumin Ou, Xumin Ou, Xumin Ou, Sai Mao, Sai Mao, Sai Mao, Qun Gao, Qun Gao, Qun Gao, Di Sun, Di Sun, Di Sun, Xingjian Wen, Xingjian Wen, Xingjian Wen, Yunya Liu, Yunya Liu, Yunya Liu, Yanling Yu, Yanling Yu, Yanling Yu, Ling Zhang, Ling Zhang, Ling Zhang, Bin Tian, Bin Tian, Leichang Pan, Leichang Pan, Xiaoyue Chen, Xiaoyue Chen, Xiaoyue Chen   +62 more
doaj   +1 more source

Equine Alphaherpesviruses Require Activation of the Small GTPases Rac1 and Cdc42 for Intracellular Transport

Microorganisms, 2020
Viruses utilize host cell signaling to facilitate productive infection. Equine herpesvirus type 1 (EHV-1) has been shown to activate Ca2+ release and phospholipase C upon contact with α4β1 integrins on the cell surface.
Oleksandr Kolyvushko, Maximilian A. Kelch, Nikolaus Osterrieder, Walid Azab   +3 more
doaj   +1 more source

EHV-1 Pathogenesis: Current in vitro Models and Future Perspectives [PDF]

, 2019
Primary infection and pathogenesis of equine herpesvirus type 1 (EHV-1) require an intricate interaction of virus with the mucosal epithelium, mononuclear cells and the vascular endothelium.
Azab, Walid, Kamel, Mohamed, Osterrieder, Klaus, Pavulraj, Selvaraj   +3 more
core   +1 more source