Results 51 to 60 of about 47,878 (245)

Central nervous system disease and genital disease in harbor porpoises (Phocoena phocoena) are associated with different herpesviruses [PDF]

open access: yes, 2016
Herpesvirus infection causes disease of variable severity in many species, including cetaceans. However, little is known about herpesvirus infection in harbor porpoises (Phocoena phocoena), despite being widespread in temperate coastal waters of the ...
Bildt, M.W.G. (Marco) van de   +7 more
core   +1 more source

Valproic Acid and Its Amidic Derivatives as New Antivirals against Alphaherpesviruses

open access: yesViruses, 2020
Herpes simplex viruses (HSVs) are neurotropic viruses with broad host range whose infections cause considerable health problems in both animals and humans.
Sabina Andreu   +3 more
doaj   +1 more source

Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure [PDF]

open access: yes, 2016
The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis.
Leib, David A   +3 more
core   +3 more sources

The precise function of alphaherpesvirus tegument proteins and their interactions during the viral life cycle

open access: yesFrontiers in Microbiology
Alphaherpesvirus is a widespread pathogen that causes diverse diseases in humans and animals and can severely damage host health. Alphaherpesvirus particles comprise a DNA core, capsid, tegument and envelope; the tegument is located between the nuclear ...
Yuxi Cui   +84 more
doaj   +1 more source

2015 Colorado Alphaherpesvirus Latency Society Symposium [PDF]

open access: yesJournal of NeuroVirology, 2015
Meeting Report on the 9th Annual Symposium of the Colorado Alphaherpesvirus Latency Society (CALS) held on May 8–11, 2019, in Vail, CO.
Randall J. Cohrs, Don Gilden
openaire   +2 more sources

Alphaherpesvirus: isolation, identification, partial characterisation, associated pathologic findings, and epidemiology in beluga whales (Delphinapterus leucas) in Alaska and Arctic Canada

open access: yesArctic Science, 2018
Live, dead stranded, and harvested belugas (Delphinapterus leucas) in Alaska and the western Canadian Arctic were screened for viruses utilizing a primary beluga cell line. Samples consisted of swabs from blowhole, anus, and genital tract.
Ole Nielsen   +4 more
doaj   +1 more source

Access to a main alphaherpesvirus receptor, located basolaterally in the respiratory epithelium, is masked by intercellular junctions [PDF]

open access: yes, 2017
The respiratory epithelium of humans and animals is frequently exposed to alphaherpesviruses, originating from either external exposure or reactivation from latency.
Hussey, Gisela S   +6 more
core   +3 more sources

Alphaherpesvirus Infection Disrupts Mitochondrial Transport in Neurons [PDF]

open access: yesCell Host & Microbe, 2012
Mitochondria are dynamic organelles that are essential for cellular metabolism but can be functionally disrupted during pathogen infection. In neurons, mitochondria are transported on microtubules via the molecular motors kinesin-1 and dynein and recruited to energy-requiring regions such as synapses.
Kramer, Tal, Enquist, Lynn W.
openaire   +2 more sources

A Common Neuronal Response to Alphaherpesvirus Infection [PDF]

open access: yesJournal of Neuroimmune Pharmacology, 2010
Alphaherpesviruses are a subfamily of the Herpesviridae that can invade the nervous system and establish either lytic or latent infections. The establishment of latent infection can occur only in neurons, indicating a unique virus-host interaction in these cells.
Moriah L, Szpara   +2 more
openaire   +2 more sources

Several Alphaherpesviruses Interact Similarly with the NF-κB Pathway and Suppress NF-κB-Dependent Gene Expression

open access: yesMicrobiology Spectrum, 2023
Alphaherpesvirus infection is associated with attenuation of different aspects of the host innate immune response that is elicited to confine primary infections at the mucosal epithelia.
Nicolás Romero   +7 more
doaj   +1 more source

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