Hyaluronan Mediates Cold-Induced Adipose Tissue Beiging
CellsAdipose tissue beiging refers to the process by which beige adipocytes emerge in classical white adipose tissue depots. Beige adipocytes dissipate chemical energy and secrete adipokines, such as classical brown adipocytes, to improve systemic metabolism,
Xi Chen +8 more
doaj +4 more sources
Endocrine disrupting chemicals: Friend or foe to brown and beige adipose tissue? [PDF]
Toxicology, 2021 Colette Miller +2 more
exaly +2 more sources
Beige Adipose Tissue Identification and Marker Specificity-Overview. [PDF]
Front Endocrinol (Lausanne), 2021 Adipose tissue (AT) is classified based on its location, physiological and functional characteristics. Although there is a clear demarcation of anatomical and molecular features specific to white (WAT) and brown adipose tissue (BAT), the factors that uniquely differentiate beige AT (BeAT) remain to be fully elaborated.
Pilkington AC, Paz HA, Wankhade UD.
europepmc +5 more sources
Brown and Beige Adipose Tissue: Therapy for Obesity and Its Comorbidities? [PDF]
Endocrinol Metab Clin North Am, 2016 Mulya A, Kirwan JP.
europepmc +3 more sources
Brown and Beige Adipose Tissue: One or Different Targets for Treatment of Obesity and Obesity-Related Metabolic Disorders? [PDF]
International Journal of Molecular SciencesAlina Babenko, Taisiia Tuchina
exaly +2 more sources
Hydrogel-Based Engineering of Beige Adipose Tissue. [PDF]
J Mater Chem B, 2015 Brown and beige adipose tissues have a significant capacity for energy expenditure that may be exploited as a treatment for obesity and metabolic disease.
Vaicik MK +8 more
europepmc +4 more sources
Mirabegron: The most promising adipose tissue beiging agent [PDF]
Physiological Reports, 2021 Accumulation of white adipose tissue (WAT) underlies the obesity epidemic, leading to current therapeutic techniques that are being investigated for their ability to activate/"beige" this tissue. Adipose tissue (AT) beiging has been reported through intermittent cold exposure (CE), exercise, and β3-Adrenergic Receptor (β3AR) agonists.
Jocelyn S. Bel +3 more
openaire +3 more sources
Scalable Generation of Pre‐Vascularized and Functional Human Beige Adipose Organoids
Advanced Science, 2023 Obesity and type 2 diabetes are becoming a global sociobiomedical burden. Beige adipocytes are emerging as key inducible actors and putative relevant therapeutic targets for improving metabolic health.
Mélanie Escudero +17 more
doaj +1 more source
Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice. [PDF]
PLoS ONE, 2013 Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura +6 more
doaj +1 more source
Matrix-Assisted Transplantation of Functional Beige Adipose Tissue. [PDF]
Diabetes, 2015 Novel, clinically relevant, approaches to shift energy balance are urgently needed to combat metabolic disorders such as obesity and diabetes. One promising approach has been the expansion of brown adipose tissues that express uncoupling protein (UCP) 1 and thus can uncouple mitochondrial respiration from ATP synthesis.
Tharp KM +8 more
europepmc +8 more sources