Results 91 to 100 of about 5,817 (208)
Advanced Science, Volume 12, Issue 44, November 27, 2025.This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen +12 more
wiley +1 more source
Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2 [PDF]
, 2014 BACKGROUND: Early and accurate diagnosis of Plasmodium falciparum infection is important for providing appropriate treatment to patients with malaria.
Chiuan Leow +4 more
core +2 more sources
European Journal of Inorganic Chemistry, Volume 28, Issue 27, September 29, 2025.Two new platinum‐binding peptides are identified by phage display against Pt‐{100} and polycrystalline targets. Binding free energies (ΔG) are quantified on Pt‐{111} surfaces using a quartz crystal microbalance with dissipation monitoring. Synchrotron radiation circular dichroism (SRCD) reveals facet‐dependent conformational adaptation on cubic (Pt ...
Monika Michaelis +3 more
wiley +1 more source
Searching for M13 bacteriophage with high affinity for nanodiamond particles [PDF]
, 2013 Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Au, Ho Yin
core
The Prostate, Volume 85, Issue 13, Page 1208-1221, September 15, 2025.ABSTRACT Background N‐terminus 15 amino acid (MC16) of Annexin A1 (ANXA1) is an effective therapeutic target for tumors and tumor vasculature as it specifically localizes to the cell surface of tumor cells and tumor vascular endothelial cells. We identified the d‐type peptide (hpnevrs, dhp7) by mirror‐image phage display targeting l‐type MC16 and ...
Kai Ozaki +8 more
wiley +1 more source
Generation of human TMEM16F-specific affibodies using purified TMEM16F
Frontiers in Molecular BiosciencesIntroduction: TMEM16 family proteins are involved in a variety of functions, including ion transport, phospholipid scrambling, and the regulation of membrane proteins. Among them, TMEM16F has dual functions as a phospholipid scramblase and a nonselective
Eunyoung Kim +7 more
doaj +1 more source
Hevea genetic transformation using a single-chain variable fragment (scFv) specific to cassiicolin, the causal agent of Corynespora leaf disease [PDF]
, 2011 The pathogenic fungus Corynespora cassiicola a serious threat to rubber trees (Hevea brasiliensis); the infected leaves develop necrotic lesions and abscise, leaving the tree unproductive. The destructiveness of C.
Ezam Badarudin, Badrul +6 more
core
Improving the solubility of single domain antibodies using VH‐like hallmark residues
Protein Science, Volume 34, Issue 7, July 2025.Abstract Single domain antibodies (sdAbs) can be generated from variable regions of heavy‐chain antibodies, which lack light chain and CH1 region. They have attracted attention due to their small size and molecular characteristics. Hydrophilic hallmark amino acids at framework region 2 (FR2) are key residues involved in the solubility of sdAbs ...
Yuta Uto +9 more
wiley +1 more source
Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery [PDF]
, 2017 Brain delivery is one of the major challenges in drug development because of the high number of patients suffering from neural diseases and the low efficiency of the treatments available.
Giralt Lledó, Ernest +3 more
core +1 more source
Small, Volume 21, Issue 29, July 24, 2025.A new approach for creating highly selective recognition surfaces is reported using phage display biopanning against metal–organic nanosheets (MONs). The highest affinity peptides for three different MONs are isolated through successive biopanning rounds and their structure‐property relationships are investigated. MONs used as recognition surfaces show
Amelia C. Wood +7 more
wiley +1 more source