Identification of Peptides from a Phage Display Library for Differentiating Newcastle Disease Virus Pathotypes [PDF]
Newcastle disease virus (NDV) strains can be classified as virulent or avirulent based upon the severity of the disease.Biopanning experiments were performed using a disulfide constrained phage display heptapeptide library against three pathotypes of ...
Lee, Tong Chuan
core
Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao +14 more
wiley +1 more source
MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology
Peptides selected from phage-displayed random peptide libraries are valuable in two aspects. On one hand, these peptides are candidates for new diagnostics, therapeutics and vaccines.
Xianlong Wang +8 more
doaj +1 more source
Searching for M13 bacteriophage with high affinity for nanodiamond particles [PDF]
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Au, Ho Yin
core
This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang +11 more
wiley +1 more source
Selection of high affinity ligands to hepatitis B core antigen from a phage-displayed cyclic peptide library. [PDF]
M13 phages that display random disulfide constrained heptapeptides on their gpIII proteins were used to select for high affinity ligands to hepatitis B core antigen (HBcAg).
Ho, Kok Lian +3 more
core +1 more source
Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors
ABSTRACT G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an overview of the therapeutic GPCR‐antibody target landscape and examines the diversity ...
Catherine J. Hutchings +6 more
wiley +1 more source
Cell-Type Specific Penetrating Peptides: Therapeutic Promises and Challenges
Cell penetrating peptides (CPP), also known as protein transduction domains (PTD), are small peptides able to carry peptides, proteins, nucleic acid, and nanoparticles, including viral particles, across the cellular membranes into cells, resulting in ...
Maliha Zahid, Paul D. Robbins
doaj +1 more source
The shark-derived single-domain antibody VNAR (variable domain of new antigen receptor) has many advantageous features that make the VNAR suitable for improving current monoclonal antibody therapy deficiencies or disease diagnosis methods.
Chia-Hung Tsai +3 more
doaj +1 more source
Theranostic applications of phage display to control leishmaniasis: Selection of biomarkers for serodiagnostics, vaccination, and immunotherapy [PDF]
© 2015, Sociedade Brasileira de Medicina Tropical. All rights reserved. Phage display is a high-throughput subtractive proteomic technology used for the generation and screening of large peptide and antibody libraries.
Chávez-Fumagalli, Miguel A. +5 more
core +1 more source

