Results 71 to 80 of about 4,252 (213)
Biopanning refers to the processes of screening peptides with a high affinity to a target material. Microfluidic biopanning has advantages compared to conventional biopanning which requires large amounts of the target material and involves inefficient ...
Yoon Sung Nam (1509805) +13 more
core +1 more source
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan +10 more
wiley +1 more source
Phage binding ELISA specificity study for phage clones obtained at different stages of biopanning.
(A) after surface biopanning round 3 (B) after surface biopanning round 4A and (C) after solution biopanning round 5. Each experiment performed once only due to limited amount of phage clone stock available for testing.
Christopher T. Elliott (407641) +5 more
core +1 more source
Despite the advances in surface-display systems for directed evolution, variants with high affinity are not always enriched due to undesirable biases that increase target-unrelated variants during biopanning.
Tomoyuki Ito +9 more
doaj +1 more source
Presentation of the targets used in three rounds of sequential antigen biopanning.
Presentation of the targets used in three rounds of sequential antigen biopanning.
Klaus R. Liedl (109013) +12 more
core +1 more source
MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology
Peptides selected from phage-displayed random peptide libraries are valuable in two aspects. On one hand, these peptides are candidates for new diagnostics, therapeutics and vaccines.
Xianlong Wang +8 more
doaj +1 more source
Development of CAR Exosomes Targeting FAP for the Treatment of Intrauterine Adhesion
ABSTRACT Engineered extracellular vesicles (EVs) have emerged as promising cell‐free platforms for immunomodulation and tissue repair. In this study, we generated EVs derived from chimeric antigen receptor (CAR) T cells targeting fibroblast activation protein (FAP) and investigated their biological and therapeutic functions.
Wenyan Fu +8 more
wiley +1 more source
Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries
Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao +5 more
wiley +1 more source
Identification of monoclonal phages specific to S. suis serotype 2 after whole cell-biopanning using a monoclonal phage ELISA.
Natsinee Anudit (11607867) +4 more
core +1 more source
Cell-Type Specific Penetrating Peptides: Therapeutic Promises and Challenges
Cell penetrating peptides (CPP), also known as protein transduction domains (PTD), are small peptides able to carry peptides, proteins, nucleic acid, and nanoparticles, including viral particles, across the cellular membranes into cells, resulting in ...
Maliha Zahid, Paul D. Robbins
doaj +1 more source

