Results 51 to 60 of about 5,879 (222)

Affinity Capture Mass Spectrometry of Biomarker Proteins Using Peptide Ligands from Biopanning [PDF]

Analytical Chemistry, 2009
Affinity capture mass spectrometry was used to isolate and ionize protein A from Staphylococcus aureus from both a commercial source and cell culture lysate using matrix assisted laser desorption/ionization (MALDI) mass spectrometry. Two surfaces are compared: gold surfaces with immunoglobulin G covalently immobilized and silica surfaces with a ...
Erin M, Johnson, Walther R, Ellis, Linda S, Powers, Vicki H, Wysocki   +3 more
openaire   +2 more sources

Subtractive phage display selection from canine visceral leishmaniasis identifies novel epitopes that mimic leishmania infantum antigens with potential serodiagnosis applications [PDF]

, 2013
Visceral leishmaniasis (VL) is a zoonotic disease that is endemic to Brazil, where dogs are the main domestic parasite reservoirs, and the percentages of infected dogs living in regions where canine VL (CVL) is endemic have ranged from 10% to 62 ...
Andrade, Pedro H R, Chávez-Fumagalli, Miguel Angel, Coelho, Eduardo Anton̂io Ferraz, Costa, Lourena Emanuele, De Magalhães Soares, Danielle Ferreira, Duarte, Mariana Costa, Goulart, Luiz Ricardo, Lage, Daniela P., Lage, Paula Sousa, Lima, Mayara Ingrid Sousa, Lopes, Eliane Gonçalves Paiva, Martins, Vivian Tamietti, Menezes-Souza, Daniel, Ribeiro, Tatiana Gomes, Soto Álvarez, Manuel, Tavares, Carlos Alberto Pereira   +15 more
core   +2 more sources

Astrochemistry on the EXPOSE/ISS and BIOPAN/Foton experiments [PDF]

Proceedings of the International Astronomical Union, 2009
AbstractWe describe three space experiments designed to expose to space conditions, and more specifically to solar UV radiation, selected samples of organic and mineral material.
Cottin, H., Guan, Y. Y., Coll, Patrice, Coscia, David, Fray, N., Macari, F., Stalport, F., Raulin, François, Szopa, Cyril, Chaput, D., Viso, M., Bertrand, M., Chabin, A., Westall, F., Brack, A.   +14 more
openaire   +2 more sources

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

Development of an Anti-Zearalenone Nanobody Phage Display Library and Preparation of Specific Nanobodies

Current Issues in Molecular Biology
Zearalenone (ZEN), a toxic estrogenic mycotoxin in cereals, threatens human and animal health through reproductive, immune, and cytotoxic effects, necessitating sensitive detection methods.
Ying Zeng, Yiying Hu, Ganying Chen, Qingqing Feng, Ruiting Wang, Zhilin Zhang, Jinxian Chen, Junbin Liao, Danrong Lin, Wei Zhu   +9 more
doaj   +1 more source

Peptide Receptor‐Functionalized AuNP‐Embedded Zwitterionic Biopolymeric Nanohydrogel for Electrochemical Sclerostin Sensing

Advanced Science, Volume 13, Issue 26, 8 May 2026.
We report an electrochemical biosensor that employs biopanning‐derived affinity peptides as selective receptors on a multifunctional chitosan–zwitterionic–gold nanoparticle (CS–ZI–AuNPs) nanohydrogel interface. The CS–ZI–AuNPs nanohydrogel exhibits antifouling properties, abundant sites for stable peptide immobilization, and efficient electrochemical ...
Hyo Jeong Yang, Jae Hwan Shin, Mingi Jo, Changyeon Lee, Hyunmin Yi, Al‐Montaser Bellah H. Ali, Jong Pil Park   +6 more
wiley   +1 more source

Progress on Phage Display Technology: Tailoring Antibodies for Cancer Immunotherapy

Viruses, 2023
The search for innovative anti-cancer drugs remains a challenge. Over the past three decades, antibodies have emerged as an essential asset in successful cancer therapy.
Renato Kaylan Alves França, Igor Cabral Studart, Marcus Rafael Lobo Bezerra, Larissa Queiroz Pontes, Antonio Marcos Aires Barbosa, Marcelo Macedo Brigido, Gilvan Pessoa Furtado, Andréa Queiroz Maranhão   +7 more
doaj   +1 more source

Rapid, multiplexed microfluidic phage display [PDF]

, 2011
The development of a method for high-throughput, automated proteomic screening could impact areas ranging from fundamental molecular interactions to the discovery of novel disease markers and therapeutic targets.
Ahmad, Habib, Cui, Yue, Cung, Kellye, Jones, Sharon E., McAlpine, Michael C., Naik, Rajesh R., Slater, Russell L.   +6 more
core  

Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells [PDF]

Scientific Reports, 2017
AbstractGlioblastoma stem-like cells (GSC) are hypothesized to evade current therapies and cause tumor recurrence, contributing to poor patient survival. Existing cell surface markers for GSC are developed from embryonic or neural stem cell systems; however, currently available GSC markers are suboptimal in sensitivity and specificity.
Michael Zorniak, Paul A. Clark, Benjamin J. Umlauf, Yongku Cho, Eric V. Shusta, John S. Kuo   +5 more
openaire   +2 more sources

Development of CAR Exosomes Targeting FAP for the Treatment of Intrauterine Adhesion

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Engineered extracellular vesicles (EVs) have emerged as promising cell‐free platforms for immunomodulation and tissue repair. In this study, we generated EVs derived from chimeric antigen receptor (CAR) T cells targeting fibroblast activation protein (FAP) and investigated their biological and therapeutic functions.
Wenyan Fu, Kewen Qian, Hongru Ai, Yitan Zou, Yaping Zhou, Ruixue Mao, Jian Zhao, Changhai Lei, Shi Hu   +8 more
wiley   +1 more source