Results 31 to 40 of about 5,879 (222)

Biopanning the mimotopes of aflatoxin B1 and their immunogenicity [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020
RESUMO Utilizando um anticorpo monoclonal contra a aflatoxina B1 (AFB1) como ligante, foi identificado um mimotopo específico de aflatoxina B1 após se realizarem quatro ciclos de seleção biológica de 7-peptídeos aleatórios em biblioteca de fago exibida. O mimotopo é denominado P10, e sua sequência de aminoácidos é YRRHEKD.
J. Zhou, F. Chen, J. Li, C. Li, Y. Qi, H. Liu, G. Zhang, A. Wang   +7 more
openaire   +3 more sources

Expression of anti-Z-DNA single chain antibody variable fragment on the filamentous phage surface

Brazilian Journal of Medical and Biological Research, 2000
We describe the expression of an anti-Z-DNA single chain variable region antibody fragment (scFv) on a filamentous phage surface. Four vectors for phage display were constructed.
A.Q. Maranhão, M.M. Brígido
doaj   +1 more source

Preparation of hexagonal GeO2 particles with particle size and crystallinity controlled by peptides, silk and silk-peptide chimeras [PDF]

, 2014
We demonstrate the use of silk based proteins to control the particle/crystallite size during GeO2 formation, using a bio-mimetic approach at circumneutral pH and ambient temperature. Multicrystalline GeO2 was prepared from germanium tetraethoxide (TEOG)
Avanzato, Belton, Brown, Brunner, Canabady-Rochelle, Carole C. Perry, Chiu, Cohen-Karni, Coradin, Davis, Devyatykh, Dickerson, Dickerson, Dickerson, Ellwood, Estefania Boix, Feng, Fleming, Foo, Gosline, Gulrajani, Inoue, Kanno, Kawai, Kim, Kim, Kim, Lawrence, Lippincott, Micoulaut, Mieszawska, Mieszawska, Murphy, Parker, Patwardhan, Perez-Rigueiro, Puddu, Puddu, Scherrer, Sewell, Slocik, Smith, Sofia, Valeria Puddu, Wu, Wu, Young, Zhou   +47 more
core   +1 more source

Biopanning data bank 2018: hugging next generation phage display [PDF]

Database, 2018
AbstractThe 2018 update of the biopanning data bank (BDB) stores phage display data sequenced by Sanger sequencing and next generation sequencing technologies. In this work, we upgraded the database with more biopanning data sets and several new features, including (i) incorporation of next generation biopanning data and the unselected population where
He, Bifang, Jiang, Lixu, Duan, Yaocong, Chai, Guoshi, Fang, Yewei, Kang, Juanjuan, Yu, Min, Li, Ning, Tang, Zhongjie, Yao, Pengcheng, Wu, Pengcheng, Derda, Ratmir, Huang, Jian   +12 more
openaire   +2 more sources

Structural basis of IL-23 antagonism by an Alphabody protein scaffold [PDF]

, 2014
Protein scaffolds can provide a promising alternative to antibodies for various biomedical and biotechnological applications, including therapeutics.
Bloch, Yehudi, Deroo, Sabrina, Desmet, Johan, Devreese, Bart, Henderikx, Paula, Hettmann, Thore, Lasters, Ignace, Lorent, Eric, Loverix, Stefan, Savvides, Savvas, Somers, Klaartje, Vandenbroucke, Karen, Verstraete, Kenneth, Wen, Yurong   +13 more
core   +1 more source

Bacteriophages as Therapeutic and Diagnostic Vehicles in Cancer

Pharmaceuticals, 2021
Evolution of nanomedicine is the re-design of synthetic and biological carriers to implement novel theranostic platforms. In recent years, bacteriophage research favors this process, which has opened up new roads in drug and gene delivery studies.
Valentina Foglizzo, Serena Marchiò
doaj   +1 more source

PuLSE:Quality control and quantification of peptide sequences explored by phage display libraries [PDF]

, 2018
The design of highly diverse phage display libraries is based on assumption that DNA bases are incorporated at similar rates within the randomized sequence.
A Gonzalez-Techera, A Haque, A Koide, A Skerra, Alastair Kerr, D Neri, DJ Rodi, DR Burton, DX Dong, E Munoz, Emmanuel Dias-Neto, F Breitling, G Winter, GA Kuzmicheva, GP Smith, GP Smith, GP Smith, H Engelberg-Kulka, HM Azzazy, HR Hoogenboom, HR Hoogenboom, J McCafferty, J Wojcik, Joanna Koszela, JW Kehoe, KA Noren, L Makowski, LT Brinton, Manfred Auer, P Ewels, RC Ladner, RJ Hosse, SC Schuster, Stefan Mann, Steven Shave, T Clackson, T Lindner, V Böttger   +37 more
core   +9 more sources

Sheep polyclonal antibody to map Haemonchus contortus mimotopes using phage display library

Revista Brasileira de Parasitologia Veterinária, 2018
The aim of this study was to evaluate phage display technology for mapping Haemonchus contortus mimotopes. We screened the PhD-7 Phage Display Peptide Library Kit with a sheep polyclonal antibody against H. contortus.
Andréia Buzatti, Arnielis Diaz Fernandez, Amilcar Arenal, Erlán Pereira, Alda Lucia Gomes Monteiro, Marcelo Beltrão Molento   +5 more
doaj   +1 more source

Novel Biopanning Strategy To Identify Epitopes Associated with Vaccine Protection [PDF]

Journal of Virology, 2013
ABSTRACTIdentifying immune correlates of protection is important to develop vaccines against infectious diseases. We designed a novel, universally applicable strategy to profile the antibody (Ab) repertoire of protected vaccine recipients, using recombinant phages encoding random peptide libraries.
Barbara C, Bachler, Michael, Humbert, Brisa, Palikuqi, Nagadenahalli B, Siddappa, Samir K, Lakhashe, Robert A, Rasmussen, Ruth M, Ruprecht   +6 more
openaire   +2 more sources

Application of Next Generation Sequencing (NGS) in Phage Displayed Peptide Selection to Support the Identification of Arsenic-Binding Motifs

Viruses, 2020
Next generation sequencing (NGS) in combination with phage surface display (PSD) are powerful tools in the newly equipped molecular biology toolbox for the identification of specific target binding biomolecules. Application of PSD led to the discovery of
Robert Braun, Nora Schönberger, Svenja Vinke, Franziska Lederer, Jörn Kalinowski, Katrin Pollmann   +5 more
doaj   +1 more source