Results 41 to 50 of about 11,198,861 (420)
eLife, 2022 In recent years, live-imaging techniques have been developed for the adult midgut of Drosophila melanogaster that allow temporal characterization of key processes involved in stem cell and tissue homeostasis.
Marco Marchetti +2 more
doaj +1 more source
Nature Communications, 2021 How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data.
Jiangping He +11 more
doaj +1 more source
Cancer Discovery, 2021 Single-cell RNA sequencing analysis of over 200,000 gastric cancer cells forms a comprehensive molecular atlas, identifying novel cell lineages and unique interactions between tumor cells and the surrounding microenvironment.
Vikrant Kumar +23 more
semanticscholar +1 more source
The IEEE Conference on Computer Vision and Pattern Recognition
(CVPR), 2016, pp. 5926-5935, 2015 Lineage tracing, the tracking of living cells as they move and divide, is a central problem in biological image analysis. Solutions, called lineage forests, are key to understanding how the structure of multicellular organisms emerges. We propose an integer linear program (ILP) whose feasible solutions define a decomposition of each image in a sequence
arxiv +1 more source
A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells. [PDF]
, 2019 Pancreatic endocrine cell differentiation is orchestrated by the action of transcription factors that operate in a gene regulatory network to activate endocrine lineage genes and repress lineage-inappropriate genes.
Carrano, Andrea C +15 more
core +2 more sources
Cell Lineage Infidelity in PDAC Progression and Therapy Resistance
Frontiers in Cell and Developmental Biology, 2021 Infidelity to cell fate occurs when differentiated cells lose their original identity and either revert to a more multipotent state or transdifferentiate into a different cell type, either within the same embryonic lineage or in an entirely different one.
Antonia Malinova +6 more
doaj +1 more source
Annual Review of Immunology, 2013 Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes ...
M. Merad +4 more
semanticscholar +1 more source
The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells. [PDF]
, 2014 BackgroundIdentification and characterization of molecular controls that regulate mammary stem and progenitor cell homeostasis are critical to our understanding of normal mammary gland development and its pathology.ResultsWe demonstrate that conditional ...
Band, Hamid +7 more
core +2 more sources
Cell lineage: Compartments and Capricious [PDF]
Current Biology, 2001 Until recently, little was known about the mechanisms that prevent cell migration across compartment boundaries in Drosophila. A new report suggests that the lineage restriction between the dorsal and ventral compartments of the developing wing relies in part on the transmembrane proteins, Capricious and Tartan.
openaire +3 more sources
Cell Identification and Cell Lineage Analysis [PDF]
, 2011 Caenorhabditis elegans is uniquely suited to the analysis of cell lineage patterns. C. elegans has a small number of somatic cells whose position and morphology are almost invariant from animal to animal. Because C. elegans is virtually transparent, cells can be identified in live animals using a simple bright-field microscopy technique, Nomarski ...
Andrew D. Chisholm +1 more
openaire +3 more sources